Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent Kinases
Paruch, Kamil, Dwyer, Michael P, Alvarez, Carmen, Brown, Courtney, Chan, Tin-Yau, Doll, Ronald J, Keertikar, Kerry, Knutson, Chad, McKittrick, Brian, Rivera, Jocelyn, Rossman, Randall, Tucker, Greg, Fischmann, Thierry, Hruza, Alan, Madison, Vincent, Nomeir, Amin A, Wang, Yaolin, Kirschmeier, Paul, Lees, Emma, Parry, David, Sgambellone, Nicole, Seghezzi, Wolfgang, Schultz, Lesley, Shanahan, Frances, Wiswell, Derek, Xu, Xiaoying, Zhou, Quiao, James, Ray A, Paradkar, Vidyadhar M, Park, Haengsoon, Rokosz, Laura R, Stauffer, Tara M, Guzi, Timothy J
Published in ACS medicinal chemistry letters (12.08.2010)
Published in ACS medicinal chemistry letters (12.08.2010)
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Journal Article
Design, Synthesis, and Activity of 2-Imidazol-1-ylpyrimidine Derived Inducible Nitric Oxide Synthase Dimerization Inhibitors
Davey, David D, Adler, Marc, Arnaiz, Damian, Eagen, Keith, Erickson, Shawn, Guilford, William, Kenrick, Margaret, Morrissey, Michael M, Ohlmeyer, Mike, Pan, Gonghua, Paradkar, Vidyadhar M, Parkinson, John, Polokoff, Mark, Saionz, Kurt, Santos, Cecile, Subramanyam, Babu, Vergona, Ron, Wei, Robert G, Whitlow, Marc, Ye, Bin, Zhao, Zuchun (Spring), Devlin, James J, Phillips, Gary
Published in Journal of medicinal chemistry (22.03.2007)
Published in Journal of medicinal chemistry (22.03.2007)
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Journal Article
Pyrazolo[1,5- a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2
Paruch, Kamil, Dwyer, Michael P., Alvarez, Carmen, Brown, Courtney, Chan, Tin-Yau, Doll, Ronald J., Keertikar, Kerry, Knutson, Chad, McKittrick, Brian, Rivera, Jocelyn, Rossman, Randall, Tucker, Greg, Fischmann, Thierry O., Hruza, Alan, Madison, Vincent, Nomeir, Amin A., Wang, Yaolin, Lees, Emma, Parry, David, Sgambellone, Nicole, Seghezzi, Wolfgang, Schultz, Lesley, Shanahan, Fran, Wiswell, Derek, Xu, Xiaoying, Zhou, Quiao, James, Ray A., Paradkar, Vidyadhar M., Park, Haengsoon, Rokosz, Laura R., Stauffer, Tara M., Guzi, Timothy J.
Published in Bioorganic & medicinal chemistry (15.11.2007)
Published in Bioorganic & medicinal chemistry (15.11.2007)
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Journal Article
Novel pyrrolidine heterocycles as CCR1 antagonists
Merritt, J. Robert, James, Ray, Paradkar, Vidyadhar M., Zhang, Chongwu, Liu, Ruiyan, Liu, Jinqi, Jacob, Biji, Chiriac, Camelia, Ohlmeyer, Michael J., Quadros, Elizabeth, Wines, Pamela, Postelnek, Jennifer, Hicks, Catherine M., Chen, Weiqing, Kimble, Earl F., O’Brien, Linda, White, Nicole, Desai, Hema, Appell, Kenneth C., Webb, Maria L.
Published in Bioorganic & medicinal chemistry letters (15.09.2010)
Published in Bioorganic & medicinal chemistry letters (15.09.2010)
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Journal Article
2-Benzimidazolyl-9-(chroman-4-yl)-purinone derivatives as JAK3 inhibitors
Cole, Andrew G., Bohnstedt, Adolph C., Paradkar, Vidyadhar, Kingsbury, Celia, Quintero, Jorge G., Park, Haengsoon, Lu, Yingchun, You, Ming, Neagu, Irina, Diller, David J., Letourneau, Jeffrey J., Shao, Yuefei, James, Ray A., Riviello, Christopher M., Ho, Koc-Kan, Lin, Tsung H., Wang, Bojing, Appell, Kenneth C., Sills, Matthew, Quadros, Elizabeth, Kimble, Earl F., Ohlmeyer, Michael H.J., Webb, Maria L.
Published in Bioorganic & medicinal chemistry letters (01.12.2009)
Published in Bioorganic & medicinal chemistry letters (01.12.2009)
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Journal Article
LIPOPROTEIN LIPASE-ACTIVATING COMPOSITIONS COMPRISING BENZENE DERIVATES
NEAGU IRINA, PARADKAR VIDYADHAR M, OKAMURA TAKASHI, SAIONZ KURT W, OHLMEYER MICHAEL, SHIBUTANI TADAO, IWATA KOUSHI
Year of Publication 19.01.2011
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Year of Publication 19.01.2011
Patent
Conformationally defined adrenergic agents. 8. Synthesis of conformationally defined analogs of norfenfluramine. A highly stereospecific synthesis of amines from alcohols in the benzobicyclo[2.2.1]heptene system
Grunewald, Gary L, Paradkar, Vidyadhar M, Pazhenchevsky, Bharak, Pleiss, Michael A, Sall, Daniel J, Seibel, William L, Reitz, Thomas J
Published in Journal of organic chemistry (01.07.1983)
Published in Journal of organic chemistry (01.07.1983)
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Journal Article
Conformationally restricted tricyclic antidepressants. 1. Octahydrodibenzazepinonaphthyridines as rigid imipramine analogs
Martin, Arnold R, Paradkar, Vidyadhar M, Peng, Geoffrey W, Speth, Robert C, Yamamura, Henry I, Horn, Alan S
Published in Journal of medicinal chemistry (01.08.1980)
Published in Journal of medicinal chemistry (01.08.1980)
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Journal Article
SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF PAIN
PARADKAR, VIDYADHAR, SASMAL, PRADIP KUMAR, TEHIM, ASHOK, AHMED, SHAHADAT
Year of Publication 23.07.2019
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Year of Publication 23.07.2019
Patent
SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF PAIN
PARADKAR, Vidyadhar, AHMED, Shahadat, TEHIM, Ashok, SASMAL, Pradip, Kumar
Year of Publication 26.04.2017
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Year of Publication 26.04.2017
Patent