Search Results - "Papageorge, Alex G." :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

RIT1 oncoproteins escape LZTR1-mediated proteolysis

RIT1 oncoproteins escape LZTR1-mediated proteolysis

by Castel, Pau, Cheng, Alice, Cuevas-Navarro, Antonio, Everman, David B, Papageorge, Alex G, Simanshu, Dhirendra K, Tankka, Alexandra, Galeas, Jacqueline, Urisman, Anatoly, McCormick, Frank
Published in Science (American Association for the Advancement of Science) (15.03.2019)

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Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer

Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer

by Zhang, Haisheng, Schaefer, Antje, Wang, Yichen, Hodge, Richard G, Blake, Devon R, Diehl, J Nathaniel, Papageorge, Alex G, Stachler, Matthew D, Liao, Jennifer, Zhou, Jin, Wu, Zhong, Akarca, Fahire G, de Klerk, Leonie K, Derks, Sarah, Pierobon, Mariaelena, Hoadley, Katherine A, Wang, Timothy C, Church, George, Wong, Kwok-Kin, Petricoin, Emanuel F, Cox, Adrienne D, Lowy, Douglas R, Der, Channing J, Bass, Adam J
Published in Cancer discovery (01.02.2020)

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Full activity of the deleted in liver cancer 1 (DLC1) tumor suppressor depends on an LD-like motif that binds talin and focal adhesion kinase (FAK)

Full activity of the deleted in liver cancer 1 (DLC1) tumor suppressor depends on an LD-like motif that binds talin and focal adhesion kinase (FAK)

by Li, Guorong, Du, Xiaoli, Vass, William C, Papageorge, Alex G, Lowy, Douglas R, Qian, Xiaolan
Published in Proceedings of the National Academy of Sciences - PNAS (11.10.2011)

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Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1

Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1

by Tripathi, Brajendra K, Grant, Tiera, Qian, Xiaolan, Zhou, Ming, Mertins, Philipp, Wang, Dunrui, Papageorge, Alex G, Tarasov, Sergey G, Hunter, Kent W, Carr, Steven A, Lowy, Douglas R
Published in The Journal of cell biology (04.12.2017)

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CDK5 is a major regulator of the tumor suppressor DLC1

CDK5 is a major regulator of the tumor suppressor DLC1

by Tripathi, Brajendra K, Qian, Xiaolan, Mertins, Philipp, Wang, Dunrui, Papageorge, Alex G, Carr, Steven A, Lowy, Douglas R
Published in The Journal of cell biology (08.12.2014)

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Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein

Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein

by Tripathi, Brajendra K., Anderman, Meghan F., Bhargava, Disha, Boccuzzi, Luciarita, Qian, Xiaolan, Wang, Dunrui, Durkin, Marian E., Papageorge, Alex G., de Miguel, Fernando J., Politi, Katerina, Walters, Kylie J., Doroshow, James H., Lowy, Douglas R.
Published in Nature communications (03.12.2021)

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Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activities

Oncogenic inhibition by a deleted in liver cancer gene requires cooperation between tensin binding and Rho-specific GTPase-activating protein activities

by Qian, Xiaolan, Li, Guorong, Asmussen, Holly K, Asnaghi, Laura, Vass, William C, Braverman, Richard, Yamada, Kenneth M, Popescu, Nicholas C, Papageorge, Alex G, Lowy, Douglas R
Published in Proceedings of the National Academy of Sciences - PNAS (22.05.2007)

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Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis

Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis

by Crawford, Nigel P S, Qian, Xiaolan, Ziogas, Argyrios, Papageorge, Alex G, Boersma, Brenda J, Walker, Renard C, Lukes, Luanne, Rowe, William L, Zhang, Jinghui, Ambs, Stefan, Lowy, Douglas R, Anton-Culver, Hoda, Hunter, Kent W
Published in PLoS genetics (01.11.2007)

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SRC and ERK cooperatively phosphorylate DLC1 and attenuate its Rho-GAP and tumor suppressor functions

SRC and ERK cooperatively phosphorylate DLC1 and attenuate its Rho-GAP and tumor suppressor functions

by Tripathi, Brajendra K, Anderman, Meghan F, Qian, Xiaolan, Zhou, Ming, Wang, Dunrui, Papageorge, Alex G, Lowy, Douglas R
Published in The Journal of cell biology (02.09.2019)

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Abstract 4377: AKT positively regulates Rho-GTP by attenuating the GAP activity of the DLC1 tumor suppressor: a mechanistic study with translational implications

Abstract 4377: AKT positively regulates Rho-GTP by attenuating the GAP activity of the DLC1 tumor suppressor: a mechanistic study with translational implications

by Tripathi, Brajendra K., Grant, Tiera, Mertins, Philipp, Qian, Xiaolan, Wang, Dunrui, Papageorge, Alex G., Carr, Steven A., Lowy, Douglas R.
Published in Cancer research (Chicago, Ill.) (15.07.2016)

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The p21 ras C-terminus is required for transformation and membrane association

The p21 ras C-terminus is required for transformation and membrane association

by Willumsen, B M, Christensen, A, Hubbert, N L, Papageorge, A G, Lowy, D R
Published in Nature (London) (16.08.1984)

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Mechanism of activation of a human oncogene

Mechanism of activation of a human oncogene

by Tabin, C J, Bradley, S M, Bargmann, C I, Weinberg, R A, Papageorge, A G, Scolnick, E M, Dhar, R, Lowy, D R, Chang, E H
Published in Nature (London) (11.11.1982)

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The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties

The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties

by Qian, Xiaolan, Esteban, Luis, Vass, William C., Upadhyaya, Cheerag, Papageorge, Alex G., Yienger, Kate, Ward, Jerrold M., Lowy, Douglas R., Santos, Eugenio
Published in The EMBO journal (15.02.2000)

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Ras-Specific Exchange Factor GRF: Oligomerization through Its Dbl Homology Domain and Calcium-Dependent Activation of Raf

Ras-Specific Exchange Factor GRF: Oligomerization through Its Dbl Homology Domain and Calcium-Dependent Activation of Raf

by Anborgh, Pieter H., Qian, Xiaolan, Papageorge, Alex G., Vass, William C., DeClue, Jeffrey E., Lowy, Douglas R.
Published in Molecular and Cellular Biology (01.07.1999)

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N Terminus of Sos1 Ras Exchange Factor: Critical Roles for the Dbl and Pleckstrin Homology Domains

N Terminus of Sos1 Ras Exchange Factor: Critical Roles for the Dbl and Pleckstrin Homology Domains

by Qian, Xiaolan, Vass, William C., Papageorge, Alex G., Anborgh, Pieter H., Lowy, Douglas R.
Published in Molecular and Cellular Biology (01.02.1998)

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Abstract 4235: Phosphorylation of Serine 861 in the ECT2 guanine nucleotide exchange factor activates Rho family GTPases and is a biomarker for several tumor types

Abstract 4235: Phosphorylation of Serine 861 in the ECT2 guanine nucleotide exchange factor activates Rho family GTPases and is a biomarker for several tumor types

by Wang, Dunrui, Qian, Xiaolan, Eng, Sarah, Nellore, Shivani, Papageorge, Alex G., Lowy, Douglas R.
Published in Cancer research (Chicago, Ill.) (01.07.2019)

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Suppression of c- ras transformation by GTPase-activating protein

Suppression of c- ras transformation by GTPase-activating protein

by Zhang, Ke, DeClue, Jeffrey E, Vass, William C, Papageorge, Alex G, McCormick, Frank, Lowy, Douglas R
Published in Nature (London) (23.08.1990)

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Inhibition of cell growth by lovastatin is independent of ras function

Inhibition of cell growth by lovastatin is independent of ras function

by DECLUE, J. E, VASS, W. C, PAPAGEORGE, A. G, LOWY, D. R, WILLUMSEN, B. M
Published in Cancer research (Chicago, Ill.) (15.01.1991)

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Mechanistic Aspects of Signaling Through Ras in NIH 3T3 Cells

Mechanistic Aspects of Signaling Through Ras in NIH 3T3 Cells

by Zhang, Ke, Papageorge, Alex G., Lowy, Douglas R.
Published in Science (American Association for the Advancement of Science) (31.07.1992)

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Abstract 3957: SRC inhibitors dephosphorylate and reactivate the DLC1 tumor suppressor: A new biomarker of clinical response

Abstract 3957: SRC inhibitors dephosphorylate and reactivate the DLC1 tumor suppressor: A new biomarker of clinical response

by Tripathi, Brajendra K., Anderman, Meghan, Qian, Xiaolan, Zhou, Ming, Wang, Dunrui, Papageorge, Alex G., Lowy, Douglas R.
Published in Cancer research (Chicago, Ill.) (01.07.2018)

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