METABOLISM AND EXCRETION OF ERLOTINIB, A SMALL MOLECULE INHIBITOR OF EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE, IN HEALTHY MALE VOLUNTEERS
JIE LING, JOHNSON, Kim A, ZHUANG MIAO, RAKHIT, Ashok, PANTZE, Michael P, HAMILTON, Marta, LUM, Bert L, PRAKASH, Chandra
Published in Drug metabolism and disposition (01.03.2006)
Published in Drug metabolism and disposition (01.03.2006)
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The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP™) predicts in vivo metabolic inhibition
Rakhit, Ashok, Pantze, Michael P., Fettner, Scott, Jones, Hannah M., Charoin, Jean-Eric, Riek, Myriam, Lum, Bert L., Hamilton, Marta
Published in European journal of clinical pharmacology (01.01.2008)
Published in European journal of clinical pharmacology (01.01.2008)
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Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration
Zheng, Yanan, Tesar, Devin B., Benincosa, Lisa, Birnböck, Herbert, Boswell, C. Andrew, Bumbaca, Daniela, Cowan, Kyra J, Danilenko, Dimitry M., Daugherty, Ann L., Fielder, Paul J., Grimm, Hans Peter, Joshi, Amita, Justies, Nicole, Kolaitis, Gerry, Lewin-Koh, Nicholas, Li, Jing, McVay, Sami, O'Mahony, Jennifer, Otteneder, Michael, Pantze, Michael, Putnam, Wendy S., Qiu, Zhihua J., Ruppel, Jane, Singer, Thomas, Stauch, Oliver, Theil, Frank-Peter, Visich, Jennifer, Yang, Jihong, Ying, Yong, Khawli, Leslie A., Richter, Wolfgang F.
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Published in mAbs (01.03.2012)
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The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions
Fattinger, K, Funk, C, Pantze, M, Weber, C, Reichen, J, Stieger, B, Meier, P J
Published in Clinical pharmacology and therapeutics (01.04.2001)
Published in Clinical pharmacology and therapeutics (01.04.2001)
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Effect of erlotinib on CYP3A activity, evaluated in vitro and by dual probes in patients with cancer
Calvert, Hilary, Twelves, Chris, Ranson, Malcolm, Plummer, Ruth, Fettner, Scott, Pantze, Michael, Ling, Jie, Hamilton, Marta, Lum, Bert L, Rakhit, Ashok
Published in Anti-cancer drugs (01.08.2014)
Published in Anti-cancer drugs (01.08.2014)
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Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile salt export pump (Bsep) by troglitazone and troglitazone sulfate
Funk, Christoph, Pantze, Michael, Jehle, Linda, Ponelle, Christiane, Scheuermann, Gerd, Lazendic, Mirjana, Gasser, Rodolfo
Published in Toxicology (Amsterdam) (05.10.2001)
Published in Toxicology (Amsterdam) (05.10.2001)
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Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile salt export pump (Bsep) by troglitazone and troglitazone sulfate: Transmembrane export pumps: role in toxicology
FUNK, Christoph, PANTZE, Michael, JEHLE, Linda, PONELLE, Christiane, SCHEUERMANN, Gerd, LAZENDIC, Mirjana, GASSER, Rodolfo
Published in Toxicology (Amsterdam) (2001)
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Published in Toxicology (Amsterdam) (2001)
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