Modelling hepatitis D virus RNA and HBsAg dynamics during nucleic acid polymer monotherapy suggest rapid turnover of HBsAg
Shekhtman, Louis, Cotler, Scott J., Hershkovich, Leeor, Uprichard, Susan L., Bazinet, Michel, Pantea, Victor, Cebotarescu, Valentin, Cojuhari, Lilia, Jimbei, Pavlina, Krawczyk, Adalbert, Dittmer, Ulf, Vaillant, Andrew, Dahari, Harel
Published in Scientific reports (12.05.2020)
Published in Scientific reports (12.05.2020)
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Safety and Efficacy of 48 Weeks REP 2139 or REP 2165, Tenofovir Disoproxil, and Pegylated Interferon Alfa-2a in Patients With Chronic HBV Infection Naïve to Nucleos(t)ide Therapy
Bazinet, Michel, Pântea, Victor, Placinta, Gheorghe, Moscalu, Iurie, Cebotarescu, Valentin, Cojuhari, Lilia, Jimbei, Pavlina, Iarovoi, Liviu, Smesnoi, Valentina, Musteata, Tatiana, Jucov, Alina, Dittmer, Ulf, Krawczyk, Adalbert, Vaillant, Andrew
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2020)
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2020)
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Safety and efficacy of REP 2139 and pegylated interferon alfa-2a for treatment-naive patients with chronic hepatitis B virus and hepatitis D virus co-infection (REP 301 and REP 301-LTF): a non-randomised, open-label, phase 2 trial
Bazinet, Michel, Pântea, Victor, Cebotarescu, Valentin, Cojuhari, Lilia, Jimbei, Pavlina, Albrecht, Jeffrey, Schmid, Peter, Le Gal, Frédéric, Gordien, Emmanuel, Krawczyk, Adalbert, Mijočević, Hrvoje, Karimzadeh, Hadi, Roggendorf, Michael, Vaillant, Andrew
Published in The lancet. Gastroenterology & hepatology (01.12.2017)
Published in The lancet. Gastroenterology & hepatology (01.12.2017)
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Journal Article
Persistent Control of Hepatitis B Virus and Hepatitis Delta Virus Infection Following REP 2139‐Ca and Pegylated Interferon Therapy in Chronic Hepatitis B Virus/Hepatitis Delta Virus Coinfection
Bazinet, Michel, Pântea, Victor, Cebotarescu, Valentin, Cojuhari, Lilia, Jimbei, Pavlina, Anderson, Mark, Gersch, Jeff, Holzmayer, Vera, Elsner, Carina, Krawczyk, Adalbert, Kuhns, Mary C., Cloherty, Gavin, Dittmer, Ulf, Vaillant, Andrew
Published in Hepatology communications (01.02.2021)
Published in Hepatology communications (01.02.2021)
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Bulevirtide Combined with Pegylated Interferon for Chronic Hepatitis D
Asselah, Tarik, Chulanov, Vladimir, Lampertico, Pietro, Wedemeyer, Heiner, Streinu-Cercel, Adrian, Pântea, Victor, Lazar, Stefan, Placinta, Gheorghe, Gherlan, George S., Bogomolov, Pavel, Stepanova, Tatyana, Morozov, Viacheslav, Syutkin, Vladimir, Sagalova, Olga, Manuilov, Dmitry, Mercier, Renee-Claude, Ye, Lei, Da, Ben L., Chee, Grace, Lau, Audrey H., Osinusi, Anu, Bourliere, Marc, Ratziu, Vlad, Pol, Stanislas, Hilleret, Marie-Noëlle, Zoulim, Fabien
Published in The New England journal of medicine (11.07.2024)
Published in The New England journal of medicine (11.07.2024)
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Journal Article
Benefit of transaminase elevations in establishing functional cure of HBV infection during nap‐based combination therapy
Bazinet, Michel, Pântea, Victor, Placinta, Gheorghe, Moscalu, Iurie, Cebotarescu, Valentin, Cojuhari, Lilia, Jimbei, Pavlina, Iarovoi, Liviu, Smesnoi, Valentina, Musteata, Tatiana, Jucov, Alina, Dittmer, Ulf, Krawczyk, Adalbert, Vaillant, Andrew
Published in Journal of viral hepatitis (01.05.2021)
Published in Journal of viral hepatitis (01.05.2021)
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Rapid monophasic HBsAg decline during nucleic-acid polymer-based therapy predicts functional cure
Hershkovich, Leeor, Shekhtman, Louis, Bazinet, Michel, Pântea, Victor, Placinta, Gheorge, Cotler, Scott J, Vaillant, Andrew, Dahari, Harel
Published in Hepatology communications (01.08.2023)
Published in Hepatology communications (01.08.2023)
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Journal Article
HBsAg isoform dynamics during NAP‐based therapy of HBeAg‐negative chronic HBV and HBV/HDV infection
Bazinet, Michel, Anderson, Mark, Pântea, Victor, Placinta, Gheorghe, Moscalu, Iurie, Cebotarescu, Valentin, Cojuhari, Lilia, Jimbei, Pavlina, Iarovoi, Liviu, Smesnoi, Valentina, Musteata, Tatina, Jucov, Alina, Dittmer, Ulf, Gersch, Jeff, Holzmayer, Vera, Kuhns, Mary, Cloherty, Gavin, Vaillant, Andrew
Published in Hepatology communications (01.08.2022)
Published in Hepatology communications (01.08.2022)
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FRI-443 Compassionate use of REP 2165-Mg in chronic HBV/HDV patients with progressive liver disease and failure to previous pegIFN therapy
Placinta, Gheorghe, Pantea, Victor, Cojuhari, Lilia, Cebotarescu, Valentin, Bazinet, Michel, Vaillant, Andrew
Published in Journal of hepatology (01.06.2024)
Published in Journal of hepatology (01.06.2024)
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Journal Article
Analysis of HBsAg Immunocomplexes and cccDNA Activity During and Persisting After NAP‐Based Therapy
Bazinet, Michel, Anderson, Mark, Pântea, Victor, Placinta, Gheorghe, Moscalu, Iurie, Cebotarescu, Valentin, Cojuhari, Lilia, Jimbei, Pavlina, Iarovoi, Liviu, Smesnoi, Valentina, Musteata, Tatina, Jucov, Alina, Dittmer, Ulf, Gersch, Jeff, Holzmayer, Vera, Kuhns, Mary, Cloherty, Gavin, Vaillant, Andrew
Published in Hepatology communications (01.11.2021)
Published in Hepatology communications (01.11.2021)
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Journal Article
GS-002 48-week off-therapy efficacy and safety of bulevirtide in combination with pegylated interferon alfa-2a in patients with chronic hepatitis delta: final results from the phase 2b, open-label, randomised, multicentre study MYR204
Asselah, Tarik, Chulanov, Vladimir, Lampertico, Pietro, Wedemeyer, Heiner, Streinu-Cercel, Adrian, Pantea, Victor, Lazar, Stefan, Gherlan, George Sebastian, Bogomolov, Pavel, Stepanova, Tatyana, Morozov, Viacheslav, Syutkin, Vladimir, Sagalova, Olga, Manuilov, Dmitry, Mercier, Renee-Claude, Ye, Lei, Chee, Grace M., Da, Ben L., Lau, Audrey H., Osinusi, Anu, Bourliere, Marc, Ratziu, Vlad, Pol, Stanislas, Hilleret, Marie-Noëlle, Zoulim, Fabien
Published in Journal of hepatology (01.06.2024)
Published in Journal of hepatology (01.06.2024)
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Journal Article
FRI-371 Undetectable HDV RNA at 24 weeks of treatment with combination therapy is an important predictor of maintained response off-therapy
Zoulim, Fabien, Chulanov, Vladimir, Lampertico, Pietro, Wedemeyer, Heiner, Streinu-Cercel, Adrian, Pantea, Victor, Lazar, Stefan, Gherlan, George Sebastian, Bogomolov, Pavel, Stepanova, Tatyana, Morozov, Viacheslav, Syutkin, Vladimir, Sagalova, Olga, Manuilov, Dmitry, Mercier, Renee-Claude, Ye, Lei, Chee, Grace M., Da, Ben L., Lau, Audrey H., Osinusi, Anu, Bourliere, Marc, Ratziu, Vlad, Pol, Stanislas, Hilleret, Marie-Noëlle, Asselah, Tarik
Published in Journal of hepatology (01.06.2024)
Published in Journal of hepatology (01.06.2024)
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Clinical and biochemical manifestation of acute viral hepatitis B in Republic of Moldova
Cojuhari, Lilia, Pântea, Victor, Plăcintă, Gheorghe, Cebotarescu, Valentin, Chirita, Olga, Crudu, Ana, Iarovoi, Liviu, Ieseanu, Zinaida, Marandici, Cristina
Published in BMC infectious diseases (15.10.2014)
Published in BMC infectious diseases (15.10.2014)
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Journal Article
Clinical and epidemiological features of acute hepatitis D viral in Republic of Moldova
Cojuhari, Lilia, Pântea, Victor, Placintă, Gheorghe, Cebotarescu, Valentin, Iarovoi, Liviu, Mereuta, Olga, Sambris, Violina, Ghitu, Elena, Gutu, Irina, Tatarciuc, Rodica
Published in BMC infectious diseases (15.10.2014)
Published in BMC infectious diseases (15.10.2014)
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Journal Article
Analysis of HBsAg levels, HBsAg isoforms, HBsAg immune complexes, HBV pregenomic RNA and HBcrAg dynamics during and after NAP-based combination therapy in the REP 301-LTF and REP 401 studies
Bazinet, Michel, Anderson, Mark, Pantea, Victor, Placinta, Gheorghe, Moscalu, Iurie, Cebotarescu, Valentin, Cojuhari, Lilia, Jimbei, Pavlina, Iarovoi, Liviu, Smesnoi, Valentina, Musteata, Tatiana, Jucov, Alina, Gersch, Jeff, Holzmayer, Vera, Kuhns, Mary, Cloherty, Gavin, Vaillant, Andrew
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
LBP33 - Analysis of HBsAg levels, HBsAg isoforms, HBsAg immune complexes, HBV pregenomic RNA and HBcrAg dynamics during and after NAP-based combination therapy in the REP 301-LTF and REP 401 studies
Bazinet, Michel, Anderson, Mark, Pantea, Victor, Placinta, Gheorghe, Moscalu, Iurie, Cebotarescu, Valentin, Cojuhari, Lilia, Jimbei, Pavlina, Iarovoi, Liviu, Smesnoi, Valentina, Musteata, Tatiana, Jucov, Alina, Gersch, Jeff, Holzmayer, Vera, Kuhns, Mary, Cloherty, Gavin, Vaillant, Andrew
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
FRI-211-Evaluation of the safety and tolerability of transaminase flares during antiviral therapy in patients with HBeAg negative chronic HBV infection or HBV/HDV co-infection
Bazinet, Michel, Pantea, Victor, Placinta, Gheorghe, Moscalu, Iurie, Cebotarescu, Valentin, Cojuhari, Lilia, Jimbei, Pavlina, Iarovoi, Liviu, Smesnoi, Valentina, Musteata, Tatiana, Jucov, Alina, Krawczyk, Adalbert, Vaillant, Andrew
Published in Journal of hepatology (01.04.2019)
Published in Journal of hepatology (01.04.2019)
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Journal Article
FRI-210-Establishment of high rates of functional cure of HBeAg negative chronic HBV infection with REP 2139-Mg based combination therapy: Ongoing follow-up results from the REP 401 study
Bazinet, Michel, Pantea, Victor, Placinta, Gheorghe, Moscalu, Iurie, Cebotarescu, Valentin, Cojuhari, Lilia, Jimbei, Pavlina, Iarovoi, Liviu, Smesnoi, Valentina, Musteata, Tatiana, Jucov, Alina, Krawczyk, Adalbert, Vaillant, Andrew
Published in Journal of hepatology (01.04.2019)
Published in Journal of hepatology (01.04.2019)
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Journal Article
FRI-168-Understanding HDV and HBsAg kinetics during nucleic acid polymer REP 2139 mono-therapy in HBeAg-negative chronic HBV/HDV co-infected patients via mathematical modeling
Shekhtman, Louis, Cotler, Scott, Uprichard, Susan, Bazinet, Michel, Pantea, Victor, Cebotarescu, Valentin, Cojuhari, Lilia, Jimbei, Pavlina, Krawczyk, Adalbert, Vaillant, Andrew, Dahari, Harel
Published in Journal of hepatology (01.04.2019)
Published in Journal of hepatology (01.04.2019)
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Journal Article
Clostridium difficile infection in the intensive care unit
Gheorghe Placinta, Valentina Vorojbit, Victor Pantea, Lilia Cojuhari, Valentin Cebotarescu, Lidia Placinta, Dan Croitoru
Published in The Moldovan Medical Journal (01.10.2020)
Published in The Moldovan Medical Journal (01.10.2020)
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