Genomic landscape of metastatic breast cancer identifies preferentially dysregulated pathways and targets
Paul, Matt R, Pan, Tien-Chi, Pant, Dhruv K, Shih, Natalie Nc, Chen, Yan, Harvey, Kyra L, Solomon, Aaron, Lieberman, David, Morrissette, Jennifer Jd, Soucier-Ernst, Danielle, Goodman, Noah G, Stavropoulos, S William, Maxwell, Kara N, Clark, Candace, Belka, George K, Feldman, Michael, DeMichele, Angela, Chodosh, Lewis A
Published in The Journal of clinical investigation (01.08.2020)
Published in The Journal of clinical investigation (01.08.2020)
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Journal Article
Notch promotes recurrence of dormant tumor cells following HER2/neu-targeted therapy
Abravanel, Daniel L, Belka, George K, Pan, Tien-chi, Pant, Dhruv K, Collins, Meredith A, Sterner, Christopher J, Chodosh, Lewis A
Published in The Journal of clinical investigation (01.06.2015)
Published in The Journal of clinical investigation (01.06.2015)
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Journal Article
Ceramide kinase promotes tumor cell survival and mammary tumor recurrence
Payne, Ania W, Pant, Dhruv K, Pan, Tien-Chi, Chodosh, Lewis A
Published in Cancer research (Chicago, Ill.) (01.11.2014)
Published in Cancer research (Chicago, Ill.) (01.11.2014)
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Journal Article
Impact of obesity on breast cancer recurrence and minimal residual disease
Ecker, Brett L, Lee, Jun Y, Sterner, Christopher J, Solomon, Aaron C, Pant, Dhruv K, Shen, Fei, Peraza, Javier, Vaught, Lauren, Mahendra, Samyukta, Belka, George K, Pan, Tien-Chi, Schmitz, Kathryn H, Chodosh, Lewis A
Published in Breast cancer research : BCR (13.03.2019)
Published in Breast cancer research : BCR (13.03.2019)
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Journal Article
PAQR8 promotes breast cancer recurrence and confers resistance to multiple therapies
Chen, Saisai, Paul, Matt R, Sterner, Christopher J, Belka, George K, Wang, Dezhen, Xu, Peining, Sreekumar, Amulya, Pan, Tien-Chi, Pant, Dhruv K, Makhlin, Igor, DeMichele, Angela, Mesaros, Clementina, Chodosh, Lewis A
Published in Breast cancer research : BCR (03.01.2023)
Published in Breast cancer research : BCR (03.01.2023)
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Journal Article
Cellular dormancy in minimal residual disease following targeted therapy
Ruth, Jason R, Pant, Dhruv K, Pan, Tien-Chi, Seidel, Hans E, Baksh, Sanjeethan C, Keister, Blaine A, Singh, Rita, Sterner, Christopher J, Bakewell, Suzanne J, Moody, Susan E, Belka, George K, Chodosh, Lewis A
Published in Breast cancer research : BCR (04.06.2021)
Published in Breast cancer research : BCR (04.06.2021)
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Journal Article
B3GALT6 promotes dormant breast cancer cell survival and recurrence by enabling heparan sulfate-mediated FGF signaling
Sreekumar, Amulya, Lu, Michelle, Choudhury, Biswa, Pan, Tien-chi, Pant, Dhruv K., Lawrence-Paul, Matthew R., Sterner, Christopher J., Belka, George K., Toriumi, Takashi, Benz, Brian A., Escobar-Aguirre, Matias, Marino, Francesco E., Esko, Jeffrey D., Chodosh, Lewis A.
Published in Cancer cell (08.01.2024)
Published in Cancer cell (08.01.2024)
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Journal Article
Rare subclonal sequencing of breast cancers indicates putative metastatic driver mutations are predominately acquired after dissemination
Lawrence-Paul, Matthew R, Pan, Tien-Chi, Pant, Dhruv K, Shih, Natalie N C, Chen, Yan, Belka, George K, Feldman, Michael, DeMichele, Angela, Chodosh, Lewis A
Published in Genome medicine (06.02.2024)
Published in Genome medicine (06.02.2024)
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Journal Article
Par-4 Downregulation Promotes Breast Cancer Recurrence by Preventing Multinucleation following Targeted Therapy
Alvarez, James V., Pan, Tien-chi, Ruth, Jason, Feng, Yi, Zhou, Alice, Pant, Dhruv, Grimley, Joshua S., Wandless, Thomas J., DeMichele, Angela, Chodosh, Lewis A.
Published in Cancer cell (08.07.2013)
Published in Cancer cell (08.07.2013)
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Journal Article
SPSB1 promotes breast cancer recurrence by potentiating c-MET signaling
Feng, Yi, Pan, Tien-Chi, Pant, Dhruv K, Chakrabarti, Kristi R, Alvarez, James V, Ruth, Jason R, Chodosh, Lewis A
Published in Cancer discovery (01.07.2014)
Published in Cancer discovery (01.07.2014)
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Journal Article
HIF-2α deletion promotes Kras-driven lung tumor development
Mazumdar, Jolly, Hickey, Michele M., Pant, Dhruv K., Durham, Amy C., Sweet-Cordero, Alejandro, Vachani, Anil, Jacks, Tyler, Chodosh, Lewis A., Kissil, Joseph L., Simon, M. Celeste, Keith, Brian, McKnight, Steven L.
Published in Proceedings of the National Academy of Sciences - PNAS (10.08.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (10.08.2010)
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Journal Article
miR-211 Is a Prosurvival MicroRNA that Regulates chop Expression in a PERK-Dependent Manner
Chitnis, Nilesh S., Pytel, Dariusz, Bobrovnikova-Marjon, Ekaterina, Pant, Dhruv, Zheng, Hui, Maas, Nancy L., Frederick, Brian, Kushner, Jake A., Chodosh, Lewis A., Koumenis, Constantinos, Fuchs, Serge Y., Diehl, J. Alan
Published in Molecular cell (09.11.2012)
Published in Molecular cell (09.11.2012)
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Journal Article
Combinatorial therapy discovery using mixed integer linear programming
Pang, Kaifang, Wan, Ying-Wooi, Choi, William T., Donehower, Lawrence A., Sun, Jingchun, Pant, Dhruv, Liu, Zhandong
Published in Bioinformatics (15.05.2014)
Published in Bioinformatics (15.05.2014)
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Journal Article
Abstract 4985: Cellular dormancy in residual disease following oncogene inhibition
Ruth, Jason, Pant, Dhruv, Keister, Blaine, Sterner, Christopher, Chodosh, Lewis
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Abstract 2894: Notch signaling promotes survival and recurrence of dormant mammary tumor cells following HER2/neu targeted therapy
Abravanel, Daniel L., Collins, Meredith A., Belka, George K., Pan, Tien-chi, Pant, Dhruv K., Sterner, Christopher J., Chodosh, Lewis A.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Life History of Metastatic Breast Cancer Reveals Promising Therapeutic Targets
Paul, Matt R, Pan, Tien-chi, Pant, Dhruv, Shih, Natalie, Chen, Yan, Lee, L Alex, Solomon, Aaron, Lieberman, David, Morrissette, Jennifer J D, Soucier-Ernst, Danielle, Stavropoulos, William, Maxwell, Kara N, Clark, Candace, Belka, George K, Feldman, Michael, DeMichele, Angela, Chodosh, Lewis A
Published in Human heredity (01.06.2018)
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Published in Human heredity (01.06.2018)
Journal Article
Par-4 Down-regulation Promotes Breast Cancer Recurrence by Preventing Multinucleation following Targeted Therapy
Alvarez, James V., Pan, Tien-chi, Ruth, Jason, Feng, Yi, Zhou, Alice, Pant, Dhruv, Grimley, Joshua S., Wandless, Thomas J., DeMichele, Angela, Chodosh, Lewis A.
Published in Cancer cell (13.06.2013)
Published in Cancer cell (13.06.2013)
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Journal Article