A complete tool set for molecular QTL discovery and analysis
Delaneau, Olivier, Ongen, Halit, Brown, Andrew A., Fort, Alexandre, Panousis, Nikolaos I., Dermitzakis, Emmanouil T.
Published in Nature communications (18.05.2017)
Published in Nature communications (18.05.2017)
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Journal Article
Estimating the causal tissues for complex traits and diseases
Ongen, Halit, Brown, Andrew A, Delaneau, Olivier, Panousis, Nikolaos I, Nica, Alexandra C, Dermitzakis, Emmanouil T
Published in Nature genetics (01.12.2017)
Published in Nature genetics (01.12.2017)
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Journal Article
Population Variation and Genetic Control of Modular Chromatin Architecture in Humans
Waszak, Sebastian M., Delaneau, Olivier, Gschwind, Andreas R., Kilpinen, Helena, Raghav, Sunil K., Witwicki, Robert M., Orioli, Andrea, Wiederkehr, Michael, Panousis, Nikolaos I., Yurovsky, Alisa, Romano-Palumbo, Luciana, Planchon, Alexandra, Bielser, Deborah, Padioleau, Ismael, Udin, Gilles, Thurnheer, Sarah, Hacker, David, Hernandez, Nouria, Reymond, Alexandre, Deplancke, Bart, Dermitzakis, Emmanouil T.
Published in Cell (27.08.2015)
Published in Cell (27.08.2015)
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Journal Article
Coordinated Effects of Sequence Variation on DNA Binding, Chromatin Structure, and Transcription
Kilpinen, Helena, Waszak, Sebastian M., Gschwind, Andreas R., Raghav, Sunil K., Witwicki, Robert M., Orioli, Andrea, Migliavacca, Eugenia, Wiederkehr, Michaël, Gutierrez-Arcelus, Maria, Panousis, Nikolaos I., Yurovsky, Alisa, Lappalainen, Tuuli, Romano-Palumbo, Luciana, Planchon, Alexandra, Bielser, Deborah, Bryois, Julien, Padioleau, Ismael, Udin, Gilles, Thurnheer, Sarah, Hacker, David, Core, Leighton J., Lis, John T., Hernandez, Nouria, Reymond, Alexandre, Deplancke, Bart, Dermitzakis, Emmanouil T.
Published in Science (American Association for the Advancement of Science) (08.11.2013)
Published in Science (American Association for the Advancement of Science) (08.11.2013)
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Journal Article
MBV: a method to solve sample mislabeling and detect technical bias in large combined genotype and sequencing assay datasets
Fort, Alexandre, Panousis, Nikolaos I, Garieri, Marco, Antonarakis, Stylianos E, Lappalainen, Tuuli, Dermitzakis, Emmanouil T, Delaneau, Olivier
Published in Bioinformatics (Oxford, England) (15.06.2017)
Published in Bioinformatics (Oxford, England) (15.06.2017)
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Journal Article
Combined genetic and transcriptome analysis of patients with SLE: distinct, targetable signatures for susceptibility and severity
Panousis, Nikolaos I, Bertsias, George K, Ongen, Halit, Gergianaki, Irini, Tektonidou, Maria G, Trachana, Maria, Romano-Palumbo, Luciana, Bielser, Deborah, Howald, Cedric, Pamfil, Cristina, Fanouriakis, Antonis, Kosmara, Despoina, Repa, Argyro, Sidiropoulos, Prodromos, Dermitzakis, Emmanouil T, Boumpas, Dimitrios T
Published in Annals of the rheumatic diseases (01.08.2019)
Published in Annals of the rheumatic diseases (01.08.2019)
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Journal Article
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D
Viñuela, Ana, Varshney, Arushi, van de Bunt, Martijn, Prasad, Rashmi B., Asplund, Olof, Bennett, Amanda, Boehnke, Michael, Brown, Andrew A., Erdos, Michael R., Fadista, João, Hansson, Ola, Hatem, Gad, Howald, Cédric, Iyengar, Apoorva K., Johnson, Paul, Krus, Ulrika, MacDonald, Patrick E., Mahajan, Anubha, Manning Fox, Jocelyn E., Narisu, Narisu, Nylander, Vibe, Orchard, Peter, Oskolkov, Nikolay, Panousis, Nikolaos I., Payne, Anthony, Stitzel, Michael L., Vadlamudi, Swarooparani, Welch, Ryan, Collins, Francis S., Mohlke, Karen L., Gloyn, Anna L., Scott, Laura J., Dermitzakis, Emmanouil T., Groop, Leif, Parker, Stephen C. J., McCarthy, Mark I.
Published in Nature communications (30.09.2020)
Published in Nature communications (30.09.2020)
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Journal Article
Mapping interindividual dynamics of innate immune response at single-cell resolution
Kumasaka, Natsuhiko, Rostom, Raghd, Huang, Ni, Polanski, Krzysztof, Meyer, Kerstin B., Patel, Sharad, Boyd, Rachel, Gomez, Celine, Barnett, Sam N., Panousis, Nikolaos I., Schwartzentruber, Jeremy, Ghoussaini, Maya, Lyons, Paul A., Calero-Nieto, Fernando J., Göttgens, Berthold, Barnes, Josephine L., Worlock, Kaylee B., Yoshida, Masahiro, Nikolić, Marko Z., Stephenson, Emily, Reynolds, Gary, Haniffa, Muzlifah, Marioni, John C., Stegle, Oliver, Hagai, Tzachi, Teichmann, Sarah A.
Published in Nature genetics (01.06.2023)
Published in Nature genetics (01.06.2023)
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Journal Article
Multiallelic Copy Number Variation in ORM1 is Associated with Plasma Cell-Free DNA Levels as an Intermediate Phenotype for Venous Thromboembolism
Martin-Fernandez, Laura, Garcia-Martínez, Iris, Lopez, Sonia, Martinez-Perez, Angel, Vilalta, Noelia, Plaza, Melania, Moret, Carla, Viñuela, Ana, Brown, Andrew A, Panousis, Nikolaos I, Buil, Alfonso, Dermitzakis, Emmanouil T, Corrales, Irene, Souto, Juan Carlos, Vidal, Francisco, Soria, Jose Manuel
Published in Thrombosis and haemostasis (01.04.2023)
Published in Thrombosis and haemostasis (01.04.2023)
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Journal Article
Extensive fragmentation and re-organization of transcription in Systemic Lupus Erythematosus
Ntasis, Vasilis F., Panousis, Nikolaos I., Tektonidou, Maria G., Dermitzakis, Emmanouil T., Boumpas, Dimitrios T., Bertsias, George K., Nikolaou, Christoforos
Published in Scientific reports (06.10.2020)
Published in Scientific reports (06.10.2020)
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Journal Article
Integrated GWAS and Gene Expression Suggest ORM1 as a Potential Regulator of Plasma Levels of Cell-Free DNA and Thrombosis Risk
Lopez, Sonia, Martinez-Perez, Angel, Rodriguez-Rius, Alba, Viñuela, Ana, Brown, Andrew A., Martin-Fernandez, Laura, Vilalta, Noelia, Arús, Marc, Panousis, Nikolaos I., Buil, Alfonso, Sabater-Lleal, Maria, Souto, Juan Carlos, Dermitzakis, Emmanouil T., Soria, Jose Manuel
Published in Thrombosis and haemostasis (01.06.2022)
Published in Thrombosis and haemostasis (01.06.2022)
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Journal Article
Time-dependent genetic effects on gene expression implicate aging processes
Bryois, Julien, Buil, Alfonso, Ferreira, Pedro G, Panousis, Nikolaos I, Brown, Andrew A, Viñuela, Ana, Planchon, Alexandra, Bielser, Deborah, Small, Kerrin, Spector, Tim, Dermitzakis, Emmanouil T
Published in Genome research (01.04.2017)
Published in Genome research (01.04.2017)
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Journal Article
Allelic mapping bias in RNA-sequencing is not a major confounder in eQTL studies
Panousis, Nikolaos I, Gutierrez-Arcelus, Maria, Dermitzakis, Emmanouil T, Lappalainen, Tuuli
Published in Genome biology (20.09.2014)
Published in Genome biology (20.09.2014)
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Journal Article
An Alzheimer's disease-associated common regulatory variant in PTK2B has causal effects on microglial function
Bello, Erica, Long, Kathleen, Iwama, Sho, Steer, Juliette, Cooper, Sarah E, Kaur Alasoo, Kumasaka, Natsuhiko, Schwartzentruber, Jeremy, Panousis, Nikolaos I, Bassett, Andrew R
Published in bioRxiv (06.11.2023)
Published in bioRxiv (06.11.2023)
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Paper
Mapping interindividual dynamics of innate immune response at single-cell resolution
Kumasaka, Natsuhiko, Rostom, Raghd, Huang, Ni, Polanski, Krzysztof, Meyer, Kerstin, Patel, Sharad, Boyd, Rachel, Gomez, Celine, Barnett, Sam, Panousis, Nikolaos, Schwartzentruber, Jeremy, Ghoussaini, Maya, Lyons, Paul A, Calero-Nieto, Fernando J, Göttgens, Berthold, Barnes, Josephine L, Worlock, Kaylee B, Yoshida, Masahiro, Nikolic, Marko, Stephenson, Emily, Reynolds, Gary, Haniffa, Muzlifah, Marioni, John, Stegle, Oliver, Hagai, Tzachi, Teichmann, Sarah A
Published in bioRxiv (01.09.2021)
Published in bioRxiv (01.09.2021)
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Paper
Extensive fragmentation and re-organization of gene co-expression patterns underlie the progression of Systemic Lupus Erythematosus
Ntasis, Vasilis F, Panousis, Nikolaos I, Tektonidou, Maria G, Dermitzakis, Emmanouil T, Boumpas, Dimitrios T, Bertsias, George K, Nikolaou, Christoforos
Published in bioRxiv (29.01.2020)
Published in bioRxiv (29.01.2020)
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Paper
Genomic dissection of Systemic Lupus Erythematosus: Distinct Susceptibility, Activity and Severity Signatures
Panousis, Nikolaos I, Bertsias, George, Ongen, Halit, Gergianaki, Irini, Tektonidou, Maria, Trachana, Maria, Romano-Palumbo, Luciana, Bielser, Deborah, Howald, Cedric, Pamfil, Cristina, Fanouriakis, Antonis, Kosmara, Despoina, Repa, Argyro, Sidiropoulos, Prodromos, Dermitzakis, Emmanouil T, Boumpas, Dimitrios T
Published in bioRxiv (27.01.2018)
Published in bioRxiv (27.01.2018)
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Paper
Influence of genetic variants on gene expression in human pancreatic islets – implications for type 2 diabetes
Viñuela, Ana, Varshney, Arushi, Van De Bunt, Martijn, Prasad, Rashmi B, Asplund, Olof B, Bennett, Amanda, Boehnke, Michael B, Andrew Anand Brown, Erdos, Michael R, Fadista, João, Hansson, Ola, Gad Hatem, Howald, Cédric, Iyengar, Apoorva K, Johnson, Paul, Krus, Ulrika, Macdonald, Patrick E, Mahajan, Anubha E, Manning Fox, Jocelyn E, Narisu, Narisu, Nylander, Vibe, Orchard, Peter E, Oskolkov, Nikolay, Panousis, Nikolaos I, Payne, Anthony, Stitzel, Michael L, Vadlamudi, Swarooparani, Welch, Ryan, Collins, Francis S, Mohlke, Karen L, Gloyn, Anna L, Scott, Laura L, Dermitzakis, Emmanouil L, Groop, Leif L, Parker, Stephen Cj, Mccarthy, Mark L
Published in bioRxiv (31.05.2019)
Published in bioRxiv (31.05.2019)
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