First-in-Human Study of PF-05212384 (PKI-587), a Small-Molecule, Intravenous, Dual Inhibitor of PI3K and mTOR in Patients with Advanced Cancer
Shapiro, Geoffrey I, Bell-McGuinn, Katherine M, Molina, Julian R, Bendell, Johanna, Spicer, James, Kwak, Eunice L, Pandya, Susan S, Millham, Robert, Borzillo, Gary, Pierce, Kristen J, Han, Lixin, Houk, Brett E, Gallo, Jorge D, Alsina, Maria, Braña, Irene, Tabernero, Josep
Published in Clinical cancer research (15.04.2015)
Published in Clinical cancer research (15.04.2015)
Get full text
Journal Article
A phase 2 study of dalantercept, an activin receptor‐like kinase‐1 ligand trap, in patients with recurrent or metastatic squamous cell carcinoma of the head and neck
Jimeno, Antonio, Posner, Marshall R., Wirth, Lori J., Saba, Nabil F., Cohen, Roger B., Popa, Elizabeta C., Argiris, Athanassios, Grossmann, Kenneth F., Sukari, Ammar, Wilson, Dawn, Zhang, Xiaosha, Sun, Jade, Glasser, Chad, Attie, Kenneth M., Sherman, Matthew L., Pandya, Susan S., Weiss, Jared
Published in Cancer (01.12.2016)
Published in Cancer (01.12.2016)
Get full text
Journal Article
Abstract A071: AG-120 (ivosidenib), a first-in-class mutant IDH1 inhibitor, promotes morphologic changes and upregulates liver-specific genes in IDH1 mutant cholangiocarcinoma
Ishii, Yuko, Sigel, Carlie, Lowery, Maeve A., Goyal, Lipika, Gliser, Camelia, Jiang, Liewen, Pandya, Susan, Wu, Bin, Choe, Sung, Deshpande, Vikram
Published in Molecular cancer therapeutics (01.01.2018)
Published in Molecular cancer therapeutics (01.01.2018)
Get full text
Journal Article
Phase Ib study of the MEK inhibitor cobimetinib (GDC-0973) in combination with the PI3K inhibitor pictilisib (GDC-0941) in patients with advanced solid tumors
Shapiro, Geoffrey I., LoRusso, Patricia, Kwak, Eunice, Pandya, Susan, Rudin, Charles M., Kurkjian, Carla, Cleary, James M., Pilat, Mary Jo, Jones, Suzanne, de Crespigny, Alex, Fredrickson, Jill, Musib, Luna, Yan, Yibing, Wongchenko, Matthew, Hsieh, Hsin-Ju, Gates, Mary R., Chan, Iris T., Bendell, Johanna
Published in Investigational new drugs (01.04.2020)
Published in Investigational new drugs (01.04.2020)
Get full text
Journal Article
NIMG-33. VOLUMETRIC TUMOR MEASUREMENTS ARE SUPERIOR TO 2D BIDIRECTIONAL MEASUREMENTS IN THE EVALUATION OF IDH INHIBITION IN DIFFUSE GLIOMAS: EVIDENCE FROM A PROSPECTIVE PHASE I TRIAL OF IVOSIDENIB
Ellingson, Benjamin, Kim, Grace, Brown, Matt, Lee, Jihey, Salamon, Noriko, Steelman, Lori, Hassan, Islam, Pandya, Susan, Chun, Saewon, Wen, Patrick, Mellinghoff, Ingo K, Goldin, Jonathan, Cloughesy, Timothy
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Get full text
Journal Article
Abstract 2275: Detection of IDH1 mutations in plasma cell-free circulating tumor DNA (ctDNA) from patients with cholangiocarcinoma
Aguado-Fraile, Elia, Choe, Sung, Gliser, Camelia, Steelman, Lori, Jiang, Liewen, Fan, Bin, Le, Kha, Lowery, Maeve A., Pandya, Susan, Wu, Bin
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
NIMG-41. PH-WEIGHTED MOLECULAR MRI AS AN EARLY BIOMARKER OF METABOLIC RESPONSE TO IDH INHIBITION IN IDH MUTANT GLIOMAS
Ellingson, Benjamin, Jingwen, Yao, Hagiwara, Akifumi, Nathanson, David, Oughourlian, Talia, Wang, Chencai, Raymond, Catalina, Pope, Whitney, Salamon, Noriko, Lai, Albert, Nghiemphu, Phioanh, Everson, Richard, Kim, Won, Liau, Linda, Pandya, Susan, Steelman, Lori, Hassan, Islam, Cloughesy, Timothy
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Get full text
Journal Article
Poster: ALL-269 Safety and Pharmacokinetics of Calaspargase Pegol in Adults With Newly Diagnosed Philadelphia-Negative Acute Lymphoblastic Leukemia: A Phase 2/3 Study
Stock, Wendy, Park, Jae H., Emadi, Ashkan, Abdul-Hay, Maher, Cassaday, Ryan D., Pullarkat, Vinod, Webster, Jonathan A., Pandya, Susan, Mogul, Mark, Shvenke, Yelena, Zhu, Jian, Tessier, Adrien, DeAngelo, Daniel J.
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
Get full text
Journal Article
ALL-269 Safety and Pharmacokinetics of Calaspargase Pegol in Adults With Newly Diagnosed Philadelphia-Negative Acute Lymphoblastic Leukemia: A Phase 2/3 Study
Stock, Wendy, Park, Jae H., Emadi, Ashkan, Abdul-Hay, Maher, Cassaday, Ryan D., Pullarkat, Vinod, Webster, Jonathan A., Pandya, Susan, Mogul, Mark, Shvenke, Yelena, Zhu, Jian, Tessier, Adrien, DeAngelo, Daniel J.
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
Published in Clinical lymphoma, myeloma and leukemia (01.10.2022)
Get full text
Journal Article
Abstract 1692: Dalantercept, an ALK1 inhibitor of angiogenesis, in combination with cisplatin inhibits tumor growth in a xenograft model of squamous cell carcinoma of the head and neck
Alimzhanov, Marat, Lee, Michael, Solban, Nicolas, Pearsall, Scott, Pandya, Susan, Sherman, Matthew L., Kumar, Ravindra
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Get full text
Journal Article
552 Characteristics of the tumor microenvironment in IDH1-mutated cholangiocarcinoma patients from ClarIDHy trial
Saatcioglu, H Duygu, Valle, Juan, Macarulla, Teresa, Javle, Milind, Do-Youn, Oh, Goyal, Lipika, Conway, Jake, Iyer, Janani, Najdawi, Fedaa, Shah, Chintan, Gliser, Camelia, Pandya, Susan, Daigle, Scott, Abou-Alfa, Ghassan, Kelley, Robin
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
Get full text
Journal Article
ACTR-46. AG-120, A FIRST-IN-class MUTANT IDH1 INHIBITOR IN PATIENTS WITH RECURRENT OR PROGRESSIVE IDH1 MUTANT GLIOMA: UPDATED RESULTS FROM THE PHASE 1 NON-ENHANCING GLIOMA POPULATION
Mellinghoff, Ingo K, Touat, Mehdi, Maher, Elizabeth, De La Fuente, Macarena, Cloughesy, Timothy F, Holdhoff, Matthias, Cote, Gregory M, Burris, Howard, Janku, Filip, Huang, Ray, Young, Robert J, Ellingson, Benjamin, Nimkar, Tara, Jiang, Liewen, Ishii, Yuko, Choe, Sung, Fan, Bin, Steelman, Lori, Yen, Katharine, Bowden, Chris, Pandya, Susan, Wen, Patrick Y
Published in Neuro-oncology (Charlottesville, Va.) (06.11.2017)
Published in Neuro-oncology (Charlottesville, Va.) (06.11.2017)
Get full text
Journal Article
ACTR-46. AG120, A FIRST-IN-CLASS MUTANT IDH1 INHIBITOR IN PATIENTS WITH RECURRENT OR PROGRESSIVE IDH1 MUTANT GLIOMA: RESULTS FROM THE PHASE 1 GLIOMA EXPANSION COHORTS
Mellinghoff, Ingo K., Touat, Mehdi, Maher, Elizabeth, DeLaFuente, Macarena, Cloughesy, Timothy F., Holdhoff, Matthias, Cote, Gregory, Burris, Howard, Janku, Filip, Huang, Raymond, Young, Robert, Ellingson, Benjamin, Auer, Julia, Liu, Hua, Hurov, Jonathan, Yen, Katherine, Agresta, Sam, Attar, Eyal, Pandya, Susan, Wen, Patrick Y.
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2016)
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2016)
Get full text
Journal Article
Abstract LB-89: Clinical combination of the MEK inhibitor GDC-0973 and the PI3K inhibitor GDC-0941: A first-in-human phase Ib study in patients with advanced solid tumors
Bendell, Johanna, LoRusso, Patricia, Kwak, Eunice, Pandya, Susan, Musib, Luna, Jones, Cheryl, De Crespigny, Alex, Belvin, Marcia, McKenzie, Meghan, Gates, Mary R., Chan, Iris, Shapiro, Geoffrey
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Get full text
Journal Article