Ivosidenib in Isocitrate Dehydrogenase 1 - Mutated Advanced Glioma
Mellinghoff, Ingo K, Ellingson, Benjamin M, Touat, Mehdi, Maher, Elizabeth, De La Fuente, Macarena I, Holdhoff, Matthias, Cote, Gregory M, Burris, Howard, Janku, Filip, Young, Robert J, Huang, Raymond, Jiang, Liewen, Choe, Sung, Fan, Bin, Yen, Katharine, Lu, Min, Bowden, Chris, Steelman, Lori, Pandya, Shuchi S, Cloughesy, Timothy F, Wen, Patrick Y
Published in Journal of clinical oncology (10.10.2020)
Published in Journal of clinical oncology (10.10.2020)
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Ivosidenib and Azacitidine in IDH1-Mutated Acute Myeloid Leukemia
Montesinos, Pau, Recher, Christian, Vives, Susana, Zarzycka, Ewa, Wang, Jianxiang, Bertani, Giambattista, Heuser, Michael, Calado, Rodrigo T, Schuh, Andre C, Yeh, Su-Peng, Daigle, Scott R, Hui, Jianan, Pandya, Shuchi S, Gianolio, Diego A, de Botton, Stephane, Döhner, Hartmut
Published in The New England journal of medicine (21.04.2022)
Published in The New England journal of medicine (21.04.2022)
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Vorasidenib, a Dual Inhibitor of Mutant IDH1/2, in Recurrent or Progressive Glioma; Results of a First-in-Human Phase I Trial
Mellinghoff, Ingo K, Penas-Prado, Marta, Peters, Katherine B, Burris, 3rd, Howard A, Maher, Elizabeth A, Janku, Filip, Cote, Gregory M, de la Fuente, Macarena I, Clarke, Jennifer L, Ellingson, Benjamin M, Chun, Saewon, Young, Robert J, Liu, Hua, Choe, Sung, Lu, Min, Le, Kha, Hassan, Islam, Steelman, Lori, Pandya, Shuchi S, Cloughesy, Timothy F, Wen, Patrick Y
Published in Clinical cancer research (15.08.2021)
Published in Clinical cancer research (15.08.2021)
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CSF concentration of the anaplastic lymphoma kinase inhibitor crizotinib
Costa, Daniel B, Kobayashi, Susumu, Pandya, Shuchi S, Yeo, Wee-Lee, Shen, Zhongzhou, Tan, Weiwei, Wilner, Keith D
Published in Journal of clinical oncology (20.05.2011)
Published in Journal of clinical oncology (20.05.2011)
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Ivosidenib in IDH1-mutant, chemotherapy-refractory cholangiocarcinoma (ClarIDHy): a multicentre, randomised, double-blind, placebo-controlled, phase 3 study
Abou-Alfa, Ghassan K, Macarulla, Teresa, Javle, Milind M, Kelley, Robin K, Lubner, Sam J, Adeva, Jorge, Cleary, James M, Catenacci, Daniel V, Borad, Mitesh J, Bridgewater, John, Harris, William P, Murphy, Adrian G, Oh, Do-Youn, Whisenant, Jonathan, Lowery, Maeve A, Goyal, Lipika, Shroff, Rachna T, El-Khoueiry, Anthony B, Fan, Bin, Wu, Bin, Chamberlain, Christina X, Jiang, Liewen, Gliser, Camelia, Pandya, Shuchi S, Valle, Juan W, Zhu, Andrew X
Published in The lancet oncology (01.06.2020)
Published in The lancet oncology (01.06.2020)
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Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma
Mellinghoff, Ingo K., van den Bent, Martin J., Blumenthal, Deborah T., Touat, Mehdi, Peters, Katherine B., Clarke, Jennifer, Mendez, Joe, Yust-Katz, Shlomit, Welsh, Liam, Mason, Warren P., Ducray, François, Umemura, Yoshie, Nabors, Burt, Holdhoff, Matthias, Hottinger, Andreas F., Arakawa, Yoshiki, Sepulveda, Juan M., Wick, Wolfgang, Soffietti, Riccardo, Perry, James R., Giglio, Pierre, de la Fuente, Macarena, Maher, Elizabeth A., Schoenfeld, Steven, Zhao, Dan, Pandya, Shuchi S., Steelman, Lori, Hassan, Islam, Wen, Patrick Y., Cloughesy, Timothy F.
Published in The New England journal of medicine (17.08.2023)
Published in The New England journal of medicine (17.08.2023)
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Journal Article
Phase I Study of the Mutant IDH1 Inhibitor Ivosidenib: Safety and Clinical Activity in Patients With Advanced Chondrosarcoma
Tap, William D, Villalobos, Victor M, Cote, Gregory M, Burris, Howard, Janku, Filip, Mir, Olivier, Beeram, Murali, Wagner, Andrew J, Jiang, Liewen, Wu, Bin, Choe, Sung, Yen, Katharine, Gliser, Camelia, Fan, Bin, Agresta, Sam, Pandya, Shuchi S, Trent, Jonathan C
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
Vorasidenib and ivosidenib in IDH1-mutant low-grade glioma: a randomized, perioperative phase 1 trial
Mellinghoff, Ingo K, Lu, Min, Wen, Patrick Y, Taylor, Jennie W, Maher, Elizabeth A, Arrillaga-Romany, Isabel, Peters, Katherine B, Ellingson, Benjamin M, Rosenblum, Marc K, Chun, Saewon, Le, Kha, Tassinari, Ania, Choe, Sung, Toubouti, Youssef, Schoenfeld, Steven, Pandya, Shuchi S, Hassan, Islam, Steelman, Lori, Clarke, Jennifer L, Cloughesy, Timothy F
Published in Nature medicine (01.03.2023)
Published in Nature medicine (01.03.2023)
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Phase I Study of Neratinib in Combination With Temsirolimus in Patients With Human Epidermal Growth Factor Receptor 2–Dependent and Other Solid Tumors
GANDHI, Leena, BAHLEDA, Rastislav, KRYGOWSKI, Mizue, YALI LIANG, TURNBULL, Kathleen W, SHAPIRO, Geoffrey I, SORIA, Jean-Charles, TOLANEY, Sara M, KWAK, Eunice L, CLEARY, James M, PANDYA, Shuchi S, HOLLEBECQUE, Antoine, ABBAS, Richat, ANANTHAKRISHNAN, Revathi, BERKENBLIT, Anna
Published in Journal of clinical oncology (10.01.2014)
Published in Journal of clinical oncology (10.01.2014)
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Final Overall Survival Efficacy Results of Ivosidenib for Patients With Advanced Cholangiocarcinoma With IDH1 Mutation: The Phase 3 Randomized Clinical ClarIDHy Trial
Zhu, Andrew X, Macarulla, Teresa, Javle, Milind M, Kelley, R Kate, Lubner, Sam J, Adeva, Jorge, Cleary, James M, Catenacci, Daniel V T, Borad, Mitesh J, Bridgewater, John A, Harris, William P, Murphy, Adrian G, Oh, Do-Youn, Whisenant, Jonathan R, Lowery, Maeve A, Goyal, Lipika, Shroff, Rachna T, El-Khoueiry, Anthony B, Chamberlain, Christina X, Aguado-Fraile, Elia, Choe, Sung, Wu, Bin, Liu, Hua, Gliser, Camelia, Pandya, Shuchi S, Valle, Juan W, Abou-Alfa, Ghassan K
Published in JAMA oncology (01.11.2021)
Published in JAMA oncology (01.11.2021)
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Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245408 (XL147), an Oral Pan-Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors
SHAPIRO, Geoffrey I, RODON, Jordi, YI XU, EGILE, Coumaran, EDELMAN, Gerald, BEDELL, Cynthia, KWAK, Eunice L, BASELGA, Jose, BRANA, Irene, PANDYA, Shuchi S, SCHEFFOLD, Christian, LAIRD, A. Douglas, NGUYEN, Linh T
Published in Clinical cancer research (2014)
Published in Clinical cancer research (2014)
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Volumetric measurements are preferred in the evaluation of mutant IDH inhibition in non-enhancing diffuse gliomas: Evidence from a phase I trial of ivosidenib
Ellingson, Benjamin M, Kim, Grace Hyun J, Brown, Matt, Lee, Jihey, Salamon, Noriko, Steelman, Lori, Hassan, Islam, Pandya, Shuchi S, Chun, Saewon, Linetsky, Michael, Yoo, Bryan, Wen, Patrick Y, Mellinghoff, Ingo K, Goldin, Jonathan, Cloughesy, Timothy F
Published in Neuro-oncology (Charlottesville, Va.) (04.05.2022)
Published in Neuro-oncology (Charlottesville, Va.) (04.05.2022)
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Clinical pharmacokinetics and pharmacodynamics of ivosidenib, an oral, targeted inhibitor of mutant IDH1, in patients with advanced solid tumors
Fan, Bin, Mellinghoff, Ingo K., Wen, Patrick Y., Lowery, Maeve A., Goyal, Lipika, Tap, William D., Pandya, Shuchi S., Manyak, Erika, Jiang, Liewen, Liu, Guowen, Nimkar, Tara, Gliser, Camelia, Prahl Judge, Molly, Agresta, Sam, Yang, Hua, Dai, David
Published in Investigational new drugs (01.04.2020)
Published in Investigational new drugs (01.04.2020)
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Pharmacokinetics/pharmacodynamics of ivosidenib in advanced IDH1-mutant cholangiocarcinoma: findings from the phase III ClarIDHy study
Fan, Bin, Abou-Alfa, Ghassan K., Zhu, Andrew X., Pandya, Shuchi S., Jia, Hongxia, Yin, Feng, Gliser, Camelia, Hua, Zhaowei, Hossain, Mohammad, Yang, Hua
Published in Cancer chemotherapy and pharmacology (01.05.2024)
Published in Cancer chemotherapy and pharmacology (01.05.2024)
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Safety and activity of ivosidenib in patients with IDH1-mutant advanced cholangiocarcinoma: a phase 1 study
Lowery, Maeve A, Burris, 3rd, Howard A, Janku, Filip, Shroff, Rachna T, Cleary, James M, Azad, Nilofer S, Goyal, Lipika, Maher, Elizabeth A, Gore, Lia, Hollebecque, Antoine, Beeram, Muralidhar, Trent, Jonathan C, Jiang, Liewen, Fan, Bin, Aguado-Fraile, Elia, Choe, Sung, Wu, Bin, Gliser, Camelia, Agresta, Samuel V, Pandya, Shuchi S, Zhu, Andrew X, Abou-Alfa, Ghassan K
Published in The lancet. Gastroenterology & hepatology (01.09.2019)
Published in The lancet. Gastroenterology & hepatology (01.09.2019)
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A phase I study of VS-6063, a second-generation focal adhesion kinase inhibitor, in patients with advanced solid tumors
Jones, Suzanne F., Siu, Lillian L., Bendell, Johanna C., Cleary, James M., Razak, Albiruni R. A., Infante, Jeffrey R., Pandya, Shuchi S., Bedard, Philippe L., Pierce, Kristen J., Houk, Brett, Roberts, W. Gregory, Shreeve, S. Martin, Shapiro, Geoffrey I.
Published in Investigational new drugs (01.10.2015)
Published in Investigational new drugs (01.10.2015)
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Molecular and morphological changes induced by ivosidenib correlate with efficacy in mutant- IDH1 cholangiocarcinoma
Aguado-Fraile, Elia, Tassinari, Ania, Ishii, Yuko, Sigel, Carlie, Lowery, Maeve A, Goyal, Lipika, Gliser, Camelia, Jiang, Liewen, Pandya, Shuchi S, Wu, Bin, Bardeesy, Nabeel, Choe, Sung, Deshpande, Vikram
Published in Future oncology (London, England) (01.06.2021)
Published in Future oncology (London, England) (01.06.2021)
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A Phase Ib, Open‐Label Study of Dalantercept, an Activin Receptor‐Like Kinase 1 Ligand Trap, plus Sorafenib in Advanced Hepatocellular Carcinoma
Abou‐Alfa, Ghassan K., Miksad, Rebecca A., Tejani, Mohamedtaki A., Williamson, Stephen, Gutierrez, Martin E., Olowokure, Olugbenga O., Sharma, Manish R., El Dika, Imane, Sherman, Matthew L., Pandya, Shuchi S.
Published in The oncologist (Dayton, Ohio) (01.02.2019)
Published in The oncologist (Dayton, Ohio) (01.02.2019)
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Safety, efficacy, and PK/PD of vorasidenib in previously treated patients with mIDH1/2 hematologic malignancies: A phase 1 study
DiNardo, Courtney D., De Botton, Stéphane, Pollyea, Daniel A., Stone, Richard M., Altman, Jessica K., Fathi, Amir T., Limsakun, Tharin, Liang, Min, Choe, Sung, Hossain, Mohammad, Tron, Adriana E., Meng, Qian, Kapsalis, Stephanie M., Pandya, Shuchi S., Stein, Eytan M.
Published in American journal of hematology (01.09.2023)
Published in American journal of hematology (01.09.2023)
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