Aberrant Wnt signaling in multiple myeloma: molecular mechanisms and targeting options
van Andel, Harmen, Kocemba, Kinga A., Spaargaren, Marcel, Pals, Steven T.
Published in Leukemia (01.05.2019)
Published in Leukemia (01.05.2019)
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The clinically active BTK inhibitor PCI-32765 targets B-cell receptor– and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia
de Rooij, Martin F.M., Kuil, Annemieke, Geest, Christian R., Eldering, Eric, Chang, Betty Y., Buggy, Joseph J., Pals, Steven T., Spaargaren, Marcel
Published in Blood (15.03.2012)
Published in Blood (15.03.2012)
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A case of meningoencephalitis by the relapsing fever spirochaete Borrelia miyamotoi in Europe
Hovius, Joppe W R, MD, de Wever, Bob, MSc, Sohne, Maaike, MD, Brouwer, Matthijs C, MD, Coumou, Jeroen, MSc, Wagemakers, Alex, MD, Oei, Anneke, Knol, Henrike, Narasimhan, Sukanya, PhD, Hodiamont, Caspar J, MD, Jahfari, Setareh, MSc, Pals, Steven T, Prof, Horlings, Hugo M, MD, Fikrig, Erol, Prof, Sprong, Hein, PhD, van Oers, Marinus H J, Prof
Published in The Lancet (British edition) (17.08.2013)
Published in The Lancet (British edition) (17.08.2013)
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Methylation of Cancer-Stem-Cell-Associated Wnt Target Genes Predicts Poor Prognosis in Colorectal Cancer Patients
de Sousa E Melo, Felipe, Colak, Selcuk, Buikhuisen, Joyce, Koster, Jan, Cameron, Kate, de Jong, Joan H., Tuynman, Jurriaan B., Prasetyanti, Pramudita R., Fessler, Evelyn, van den Bergh, Saskia P., Rodermond, Hans, Dekker, Evelien, van der Loos, Chris M., Pals, Steven T., van de Vijver, Marc J., Versteeg, Rogier, Richel, Dick J., Vermeulen, Louis, Medema, Jan Paul
Published in Cell stem cell (04.11.2011)
Published in Cell stem cell (04.11.2011)
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Combined immunodeficiency with severe inflammation and allergy caused by ARPC1B deficiency
Kuijpers, Taco W., MD, PhD, Tool, Anton T.J., PhD, van der Bijl, Ivo, de Boer, Martin, van Houdt, Michel, de Cuyper, Iris M, Roos, Dirk, PhD, van Alphen, Floris, van Leeuwen, Karin, Cambridge, Emma L, Arends, Mark J., MBChB(Hons), PhD, MRCPath, Dougan, Gordon, PhD, Clare, Simon, PhD, Ramirez-Solis, Ramiro, PhD, Pals, Steven T., MD, PhD, Adams, David J., PhD, Meijer, Alexander B., PhD, van den Berg, Timo K., PhD
Published in Journal of allergy and clinical immunology (01.07.2017)
Published in Journal of allergy and clinical immunology (01.07.2017)
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Tissue-specific expression of IgG receptors by human macrophages ex vivo
Bruggeman, Christine W, Houtzager, Julia, Dierdorp, Barbara, Kers, Jesper, Pals, Steven T, Lutter, René, van Gulik, Thomas, den Haan, Joke M M, van den Berg, Timo K, van Bruggen, Robin, Kuijpers, Taco W
Published in PloS one (15.10.2019)
Published in PloS one (15.10.2019)
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MET Signaling Overcomes Epidermal Growth Factor Receptor Inhibition in Normal and Colorectal Cancer Stem Cells Causing Drug Resistance
Joosten, Sander P.J., Mizutani, Tomohiro, Spaargaren, Marcel, Clevers, Hans, Pals, Steven T.
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.10.2019)
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A loss-of-adhesion CRISPR-Cas9 screening platform to identify cell adhesion-regulatory proteins and signaling pathways
de Rooij, Martin F. M., Thus, Yvonne J., Swier, Nathalie, Beijersbergen, Roderick L., Pals, Steven T., Spaargaren, Marcel
Published in Nature communications (19.04.2022)
Published in Nature communications (19.04.2022)
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MYD88 mutations identify a molecular subgroup of diffuse large B-cell lymphoma with an unfavorable prognosis
Vermaat, Joost S, Somers, Sebastiaan F, de Wreede, Liesbeth C, Kraan, Willem, de Groen, Ruben A L, Schrader, Anne M R, Kerver, Emile D, Scheepstra, Cornelis G, Berenschot, Henriëtte, Deenik, Wendy, Wegman, Jurgen, Broers, Rianne, de Boer, Jan-Paul D, Nijland, Marcel, van Wezel, Tom, Veelken, Hendrik, Spaargaren, Marcel, Cleven, Arjen H, Kersten, Marie José, Pals, Steven T
Published in Haematologica (Roma) (01.02.2020)
Published in Haematologica (Roma) (01.02.2020)
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Immune evasion in primary testicular and central nervous system lymphomas: HLA loss rather than 9p24.1/PD-L1/PD-L2 alterations
Minderman, Marthe, Amir, Avital, Kraan, Willem, Schilder-Tol, Esther J.M., Oud, Monique E.C.M., Scheepstra, Cornelis G., Noorduyn, Arnold L., Kluin, Philip M., Kersten, Marie José, Spaargaren, Marcel, Pals, Steven T.
Published in Blood (30.09.2021)
Published in Blood (30.09.2021)
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Inhibition of casein kinase 2 sensitizes mantle cell lymphoma to venetoclax through MCL-1 downregulation
Thus, Yvonne J, De Rooij, Martin F M, Swier, Nathalie, Beijersbergen, Roderick L, Guikema, Jeroen E J, Kersten, Marie-José, Eldering, Eric, Pals, Steven T, Kater, Arnon P, Spaargaren, Marcel
Published in Haematologica (Roma) (01.03.2023)
Published in Haematologica (Roma) (01.03.2023)
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The forkhead transcription factor FOXP1 represses human plasma cell differentiation
van Keimpema, Martine, Grüneberg, Leonie J., Mokry, Michal, van Boxtel, Ruben, van Zelm, Menno C., Coffer, Paul, Pals, Steven T., Spaargaren, Marcel
Published in Blood (29.10.2015)
Published in Blood (29.10.2015)
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Journal Article
Mutations in EXTL3 Cause Neuro-immuno-skeletal Dysplasia Syndrome
Oud, Machteld M., Tuijnenburg, Paul, Hempel, Maja, van Vlies, Naomi, Ren, Zemin, Ferdinandusse, Sacha, Jansen, Machiel H., Santer, René, Johannsen, Jessika, Bacchelli, Chiara, Alders, Marielle, Li, Rui, Davies, Rosalind, Dupuis, Lucie, Cale, Catherine M., Wanders, Ronald J.A., Pals, Steven T., Ocaka, Louise, James, Chela, Müller, Ingo, Lehmberg, Kai, Strom, Tim, Engels, Hartmut, Williams, Hywel J., Beales, Phil, Roepman, Ronald, Dias, Patricia, Brunner, Han G., Cobben, Jan-Maarten, Hall, Christine, Hartley, Taila, Le Quesne Stabej, Polona, Mendoza-Londono, Roberto, Davies, E. Graham, de Sousa, Sérgio B., Lessel, Davor, Arts, Heleen H., Kuijpers, Taco W.
Published in American journal of human genetics (02.02.2017)
Published in American journal of human genetics (02.02.2017)
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High prevalence of the MYD88 L265P mutation in IgM anti-MAG paraprotein-associated peripheral neuropathy
Vos, Josephine Mathilde, Notermans, Nicolette C, D’Sa, Shirley, Lunn, Michael P, van der Pol, W Ludo, Kraan, Willem, Reilly, Mary M, Chalker, Jane, Gupta, Rajeev, Kersten, Marie-José, Pals, Steven T, Minnema, Monique C
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2018)
Published in Journal of neurology, neurosurgery and psychiatry (01.09.2018)
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Journal Article
The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma
Ren, Zemin, Lantermans, Hildo, Kuil, Annemieke, Kraan, Willem, Arenzana-Seisdedos, Fernando, Kersten, Marie José, Spaargaren, Marcel, Pals, Steven T
Published in Journal of hematology and oncology (12.01.2021)
Published in Journal of hematology and oncology (12.01.2021)
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Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis
Zeilstra, Jurrit, Joosten, Sander P J, Dokter, Maarten, Verwiel, Eugène, Spaargaren, Marcel, Pals, Steven T
Published in Cancer research (Chicago, Ill.) (15.05.2008)
Published in Cancer research (Chicago, Ill.) (15.05.2008)
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