Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model
Verret, Laure, Mann, Edward O., Hang, Giao B., Barth, Albert M.I., Cobos, Inma, Ho, Kaitlyn, Devidze, Nino, Masliah, Eliezer, Kreitzer, Anatol C., Mody, Istvan, Mucke, Lennart, Palop, Jorge J.
Published in Cell (27.04.2012)
Published in Cell (27.04.2012)
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Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer’s disease model
Sanchez, Pascal E, Zhu, Lei, Verret, Laure, Vossel, Keith A, Orr, Anna G, Cirrito, John R, Devidze, Nino, Ho, Kaitlyn, Yu, Gui-Qiu, Palop, Jorge J, Mucke, Lennart
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2012)
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A second X chromosome contributes to resilience in a mouse model of Alzheimer's disease
Davis, Emily J, Broestl, Lauren, Abdulai-Saiku, Samira, Worden, Kurtresha, Bonham, Luke W, Miñones-Moyano, Elena, Moreno, Arturo J, Wang, Dan, Chang, Kevin, Williams, Gina, Garay, Bayardo I, Lobach, Iryna, Devidze, Nino, Kim, Daniel, Anderson-Bergman, Cliff, Yu, Gui-Qiu, White, Charles C, Harris, Julie A, Miller, Bruce L, Bennett, David A, Arnold, Arthur P, De Jager, Phil L, Palop, Jorge J, Panning, Barbara, Yokoyama, Jennifer S, Mucke, Lennart, Dubal, Dena B
Published in Science translational medicine (26.08.2020)
Published in Science translational medicine (26.08.2020)
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Distinct Roles of GABAergic Interneurons in the Regulation of Striatal Output Pathways
Gittis, Aryn H, Nelson, Alexandra B, Thwin, Myo T, Palop, Jorge J, Kreitzer, Anatol C
Published in The Journal of neuroscience (10.02.2010)
Published in The Journal of neuroscience (10.02.2010)
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Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease
Palop, Jorge J., Chin, Jeannie, Roberson, Erik D., Wang, Jun, Thwin, Myo T., Bien-Ly, Nga, Yoo, Jong, Ho, Kaitlyn O., Yu, Gui-Qiu, Kreitzer, Anatol, Finkbeiner, Steven, Noebels, Jeffrey L., Mucke, Lennart
Published in Neuron (Cambridge, Mass.) (06.09.2007)
Published in Neuron (Cambridge, Mass.) (06.09.2007)
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Arc regulates spine morphology and maintains network stability in vivo
Peebles, Carol L., Yoo, Jong, Thwin, Myo T., Palop, Jorge J., Noebels, Jeffrey L., Finkbeiner, Steven, Snyder, Solomon H.
Published in Proceedings of the National Academy of Sciences - PNAS (19.10.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (19.10.2010)
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Identifying behavioral structure from deep variational embeddings of animal motion
Luxem, Kevin, Mocellin, Petra, Fuhrmann, Falko, Kürsch, Johannes, Miller, Stephanie R., Palop, Jorge J., Remy, Stefan, Bauer, Pavol
Published in Communications biology (18.11.2022)
Published in Communications biology (18.11.2022)
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GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer’s Disease Models
Hanson, Jesse E., Ma, Keran, Elstrott, Justin, Weber, Martin, Saillet, Sandrine, Khan, Abdullah S., Simms, Jeffrey, Liu, Benjamin, Kim, Thomas A., Yu, Gui-Qiu, Chen, Yelin, Wang, Tzu-Ming, Jiang, Zhiyu, Liederer, Bianca M., Deshmukh, Gauri, Solanoy, Hilda, Chan, Connie, Sellers, Benjamin D., Volgraf, Matthew, Schwarz, Jacob B., Hackos, David H., Weimer, Robby M., Sheng, Morgan, Gill, T. Michael, Scearce-Levie, Kimberly, Palop, Jorge J.
Published in Cell reports (Cambridge) (14.01.2020)
Published in Cell reports (Cambridge) (14.01.2020)
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Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease
Sanchez-Mejia, Rene O, Newman, John W, Toh, Sandy, Yu, Gui-Qiu, Zhou, Yungui, Halabisky, Brian, Cissé, Moustapha, Scearce-Levie, Kimberly, Cheng, Irene H, Gan, Li, Palop, Jorge J, Bonventre, Joseph V, Mucke, Lennart
Published in Nature neuroscience (01.11.2008)
Published in Nature neuroscience (01.11.2008)
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Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer's disease mutations but not by inhibition of BACE1
Johnson, Erik C B, Ho, Kaitlyn, Yu, Gui-Qiu, Das, Melanie, Sanchez, Pascal E, Djukic, Biljana, Lopez, Isabel, Yu, Xinxing, Gill, Michael, Zhang, Weiping, Paz, Jeanne T, Palop, Jorge J, Mucke, Lennart
Published in Molecular neurodegeneration (14.09.2020)
Published in Molecular neurodegeneration (14.09.2020)
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Machine learning reveals prominent spontaneous behavioral changes and treatment efficacy in humanized and transgenic Alzheimer's disease models
Miller, Stephanie R., Luxem, Kevin, Lauderdale, Kelli, Nambiar, Pranav, Honma, Patrick S., Ly, Katie K., Bangera, Shreya, Bullock, Mary, Shin, Jia, Kaliss, Nick, Qiu, Yuechen, Cai, Catherine, Shen, Kevin, Mallen, K. Dakota, Yan, Zhaoqi, Mendiola, Andrew S., Saito, Takashi, Saido, Takaomi C., Pico, Alexander R., Thomas, Reuben, Roberson, Erik D., Akassoglou, Katerina, Bauer, Pavol, Remy, Stefan, Palop, Jorge J.
Published in Cell reports (Cambridge) (26.11.2024)
Published in Cell reports (Cambridge) (26.11.2024)
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Fyn Kinase Induces Synaptic and Cognitive Impairments in a Transgenic Mouse Model of Alzheimer's Disease
Chin, Jeannie, Palop, Jorge J, Puolivali, Jukka, Massaro, Catherine, Bien-Ly, Nga, Gerstein, Hilary, Scearce-Levie, Kimberly, Masliah, Eliezer, Mucke, Lennart
Published in The Journal of neuroscience (19.10.2005)
Published in The Journal of neuroscience (19.10.2005)
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Neuronal Depletion of Calcium-Dependent Proteins in the Dentate Gyrus Is Tightly Linked to Alzheimer's Disease-Related Cognitive Deficits
Palop, Jorge J., Jones, Brian, Kekonius, Lisa, Chin, Jeannie, Yu, Gui-Qiu, Raber, Jacob, Masliah, Eliezer, Mucke, Lennart
Published in Proceedings of the National Academy of Sciences - PNAS (05.08.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (05.08.2003)
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Vulnerability of Dentate Granule Cells to Disruption of Arc Expression in Human Amyloid Precursor Protein Transgenic Mice
Palop, Jorge J, Chin, Jeannie, Bien-Ly, Nga, Massaro, Catherine, Yeung, Bertrand Z, Yu, Gui-Qiu, Mucke, Lennart
Published in The Journal of neuroscience (19.10.2005)
Published in The Journal of neuroscience (19.10.2005)
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Enkephalin Elevations Contribute to Neuronal and Behavioral Impairments in a Transgenic Mouse Model of Alzheimer's Disease
Meilandt, William J, Yu, Gui-Qiu, Chin, Jeannie, Roberson, Erik D, Palop, Jorge J, Wu, Tiffany, Scearce-Levie, Kimberly, Mucke, Lennart
Published in The Journal of neuroscience (07.05.2008)
Published in The Journal of neuroscience (07.05.2008)
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