PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis
Mukhopadhyay, Partha, Horváth, Béla, Rajesh, Mohanraj, Varga, Zoltán V., Gariani, Karim, Ryu, Dongryeol, Cao, Zongxian, Holovac, Eileen, Park, Ogyi, Zhou, Zhou, Xu, Ming-Jiang, Wang, Wei, Godlewski, Grzegorz, Paloczi, Janos, Nemeth, Balazs Tamas, Persidsky, Yuri, Liaudet, Lucas, Haskó, György, Bai, Peter, Boulares, A. Hamid, Auwerx, Johan, Gao, Bin, Pacher, Pal
Published in Journal of hepatology (01.03.2017)
Published in Journal of hepatology (01.03.2017)
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Activation of PPARβ/δ protects cardiac myocytes from oxidative stress-induced apoptosis by suppressing generation of reactive oxygen/nitrogen species and expression of matrix metalloproteinases
Barlaka, Eleftheria, Görbe, Anikó, Gáspár, Renáta, Pálóczi, János, Ferdinandy, Péter, Lazou, Antigone
Published in Pharmacological research (01.05.2015)
Published in Pharmacological research (01.05.2015)
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Structural basis of selective cannabinoid CB2 receptor activation
Li, Xiaoting, Chang, Hao, Bouma, Jara, de Paus, Laura V., Mukhopadhyay, Partha, Paloczi, Janos, Mustafa, Mohammed, van der Horst, Cas, Kumar, Sanjay Sunil, Wu, Lijie, Yu, Yanan, van den Berg, Richard J. B. H. N., Janssen, Antonius P. A., Lichtman, Aron, Liu, Zhi-Jie, Pacher, Pal, van der Stelt, Mario, Heitman, Laura H., Hua, Tian
Published in Nature communications (15.03.2023)
Published in Nature communications (15.03.2023)
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Chronic plus binge ethanol feeding induces myocardial oxidative stress, mitochondrial and cardiovascular dysfunction, and steatosis
Matyas, Csaba, Varga, Zoltan V, Mukhopadhyay, Partha, Paloczi, Janos, Lajtos, Tamas, Erdelyi, Katalin, Nemeth, Balazs T, Nan, Mintong, Hasko, Gyorgy, Gao, Bin, Pacher, Pal
Published in American journal of physiology. Heart and circulatory physiology (01.06.2016)
Published in American journal of physiology. Heart and circulatory physiology (01.06.2016)
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Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice
Mock, Elliot D, Mustafa, Mohammed, Gunduz-Cinar, Ozge, Cinar, Resat, Petrie, Gavin N, Kantae, Vasudev, Di, Xinyu, Ogasawara, Daisuke, Varga, Zoltan V, Paloczi, Janos, Miliano, Cristina, Donvito, Giulia, van Esbroeck, Annelot C M, van der Gracht, Anouk M F, Kotsogianni, Ioli, Park, Joshua K, Martella, Andrea, van der Wel, Tom, Soethoudt, Marjolein, Jiang, Ming, Wendel, Tiemen J, Janssen, Antonius P A, Bakker, Alexander T, Donovan, Colleen M, Castillo, Laura I, Florea, Bogdan I, Wat, Jesse, van den Hurk, Helma, Wittwer, Matthias, Grether, Uwe, Holmes, Andrew, van Boeckel, Constant A A, Hankemeier, Thomas, Cravatt, Benjamin F, Buczynski, Matthew W, Hill, Matthew N, Pacher, Pal, Lichtman, Aron H, van der Stelt, Mario
Published in Nature chemical biology (01.06.2020)
Published in Nature chemical biology (01.06.2020)
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JDP2 overexpression provokes cardiac dysfunction in mice
Heger, Jacqueline, Bornbaum, Julia, Würfel, Alona, Hill, Christian, Brockmann, Nils, Gáspár, Renáta, Pálóczi, János, Varga, Zoltán V, Sárközy, Márta, Bencsik, Péter, Csont, Tamás, Török, Szilvia, Kojonazarov, Baktybek, Schermuly, Ralph Theo, Böngler, Kerstin, Parahuleva, Mariana, Ferdinandy, Peter, Schulz, Rainer, Euler, Gerhild
Published in Scientific reports (16.05.2018)
Published in Scientific reports (16.05.2018)
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A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence
Jiang, Ming, Huizenga, Mirjam C W, Wirt, Jonah L, Paloczi, Janos, Amedi, Avand, van den Berg, Richard J B H N, Benz, Joerg, Collin, Ludovic, Deng, Hui, Di, Xinyu, Driever, Wouter F, Florea, Bogdan I, Grether, Uwe, Janssen, Antonius P A, Hankemeier, Thomas, Heitman, Laura H, Lam, Tsang-Wai, Mohr, Florian, Pavlovic, Anto, Ruf, Iris, van den Hurk, Helma, Stevens, Anna F, van der Vliet, Daan, van der Wel, Tom, Wittwer, Matthias B, van Boeckel, Constant A A, Pacher, Pal, Hohmann, Andrea G, van der Stelt, Mario
Published in Nature communications (05.12.2023)
Published in Nature communications (05.12.2023)
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Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection
Bencsik, Péter, Kupai, Krisztina, Görbe, Anikó, Kenyeres, Éva, Varga, Zoltán V, Pálóczi, János, Gáspár, Renáta, Kovács, László, Weber, Lutz, Takács, Ferenc, Hajdú, István, Fabó, Gabriella, Cseh, Sándor, Barna, László, Csont, Tamás, Csonka, Csaba, Dormán, György, Ferdinandy, Péter
Published in Frontiers in pharmacology (05.04.2018)
Published in Frontiers in pharmacology (05.04.2018)
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Cannabinoid receptor 2 activation alleviates diabetes-induced cardiac dysfunction, inflammation, oxidative stress, and fibrosis
Rajesh, Mohanraj, Mukhopadhyay, Partha, Bátkai, Sándor, Arif, Muhammad, Varga, Zoltán V., Mátyás, Csaba, Paloczi, Janos, Lehocki, Andrea, Haskó, György, Pacher, Pal
Published in GeroScience (01.06.2022)
Published in GeroScience (01.06.2022)
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Data-driven transcriptomics analysis identifies PCSK9 as a novel key regulator in liver aging
Arif, Muhammad, Matyas, Csaba, Mukhopadhyay, Partha, Yokus, Burhan, Trojnar, Eszter, Paloczi, Janos, Paes-Leme, Bruno, Zhao, Suxian, Lohoff, Falk W., Haskó, György, Pacher, Pal
Published in GeroScience (01.10.2023)
Published in GeroScience (01.10.2023)
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Correction to: Cannabinoid receptor 2 activation alleviates diabetes-induced cardiac dysfunction, inflammation, oxidative stress, and fibrosis
Rajesh, Mohanraj, Mukhopadhyay, Partha, Bátkai, Sándor, Arif, Muhammad, Varga, Zoltán V., Mátyás, Csaba, Paloczi, Janos, Lehocki, Andrea, Haskó, György, Pacher, Pal
Published in GeroScience (01.06.2022)
Published in GeroScience (01.06.2022)
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Alcohol Binge-Induced Cardiovascular Dysfunction Involves Endocannabinoid–CB1-R Signaling
Paloczi, Janos, Matyas, Csaba, Cinar, Resat, Varga, Zoltan V., Hasko, György, Schindler, Thomas H., Kunos, George, Pacher, Pal
Published in JACC. Basic to translational science (01.09.2019)
Published in JACC. Basic to translational science (01.09.2019)
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Different administration schedules of darbepoetin alfa affect oxidized and reduced glutathione levels to a similar extent in 5/6 nephrectomized rats
Monostori, Péter, Kocsis, Gabriella F., Ökrös, Zsuzsanna, Bencsik, Péter, Czétényi, Orsolya, Kiss, Zoltán, Gellén, Balázs, Bereczki, Csaba, Ocsovszki, Imre, Pipis, Judit, Pálóczi, János, Sárközy, Márta, Török, Szilvia, Varga, Ilona S., Kiss, István, Fodor, Eszter, Csont, Tamás, Ferdinandy, Péter, Túri, Sándor
Published in Clinical and experimental nephrology (01.08.2013)
Published in Clinical and experimental nephrology (01.08.2013)
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Pepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage
Petrucci, Vanessa, Chicca, Andrea, Glasmacher, Sandra, Paloczi, Janos, Cao, Zongxian, Pacher, Pal, Gertsch, Jürg
Published in Scientific reports (25.08.2017)
Published in Scientific reports (25.08.2017)
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Involvement of heart-gut axis in endocannabinoid CB1R signaling following alcohol binge
Cohen, Sarah, McTernan, Patrick, Siggins, Robert, Cinar, Resat, Pacher, Pal, Paloczi, Janos
Published in Physiology (Bethesda, Md.) (01.05.2024)
Published in Physiology (Bethesda, Md.) (01.05.2024)
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Cardioprotection by Farnesol: Role of the Mevalonate Pathway
Szűcs, Gergő, Murlasits, Zsolt, Török, Szilvia, Kocsis, Gabriella F., Pálóczi, János, Görbe, Anikó, Csont, Tamás, Csonka, Csaba, Ferdinandy, Péter
Published in Cardiovascular drugs and therapy (01.08.2013)
Published in Cardiovascular drugs and therapy (01.08.2013)
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