Tofacitinib Suppresses Several JAK-STAT Pathways in Rheumatoid Arthritis In Vivo and Baseline Signaling Profile Associates With Treatment Response
Palmroth, Maaria, Kuuliala, Krista, Peltomaa, Ritva, Virtanen, Anniina, Kuuliala, Antti, Kurttila, Antti, Kinnunen, Anna, Leirisalo-Repo, Marjatta, Silvennoinen, Olli, Isomäki, Pia
Published in Frontiers in immunology (24.09.2021)
Published in Frontiers in immunology (24.09.2021)
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Journal Article
Identification of Novel Small Molecule Ligands for JAK2 Pseudokinase Domain
Virtanen, Anniina T, Haikarainen, Teemu, Sampathkumar, Parthasarathy, Palmroth, Maaria, Liukkonen, Sanna, Liu, Jianping, Nekhotiaeva, Natalia, Hubbard, Stevan R, Silvennoinen, Olli
Published in Pharmaceuticals (Basel, Switzerland) (01.01.2023)
Published in Pharmaceuticals (Basel, Switzerland) (01.01.2023)
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Journal Article
IRF2BP2 Mutation Is Associated with Increased STAT1 and STAT5 Activation in Two Family Members with Inflammatory Conditions and Lymphopenia
Palmroth, Maaria, Viskari, Hanna, Seppänen, Mikko R. J., Keskitalo, Salla, Virtanen, Anniina, Varjosalo, Markku, Silvennoinen, Olli, Isomäki, Pia
Published in Pharmaceuticals (Basel, Switzerland) (13.08.2021)
Published in Pharmaceuticals (Basel, Switzerland) (13.08.2021)
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Journal Article
Differences in JAK Isoform Selectivity Among Different Types of JAK Inhibitors Evaluated for Rheumatic Diseases Through In Vitro Profiling
Virtanen, Anniina, Palmroth, Maaria, Liukkonen, Sanna, Kurttila, Antti, Haikarainen, Teemu, Isomäki, Pia, Silvennoinen, Olli
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.11.2023)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.11.2023)
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Journal Article
Tofacitinib treatment modulates the levels of several inflammation-related plasma proteins in rheumatoid arthritis and baseline levels of soluble biomarkers associate with the treatment response
Valli, Atte, Kuuliala, Krista, Virtanen, Anniina, Kuuliala, Antti, Palmroth, Maaria, Peltomaa, Ritva, Vidqvist, Krista-Liisa, Leirisalo-Repo, Marjatta, Silvennoinen, Olli, Isomäki, Pia
Published in Clinical and experimental immunology (15.12.2022)
Published in Clinical and experimental immunology (15.12.2022)
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Journal Article
Development of Versatile Human In Vitro Vascularized Adipose Tissue Model with Serum‐Free Angiogenesis and Natural Adipogenesis Induction
Huttala, Outi, Palmroth, Maaria, Hemminki, Pauliina, Toimela, Tarja, Heinonen, Tuula, Ylikomi, Timo, Sarkanen, Jertta‐Riina
Published in Basic & clinical pharmacology & toxicology (01.09.2018)
Published in Basic & clinical pharmacology & toxicology (01.09.2018)
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Journal Article
IRF2BP2 Mutation Is Associated with Increased STAT1 and STAT5 Activation in Two Family Members with Inflammatory Conditions and Lymphopenia
Palmroth, Maaria, Viskari, Hanna, Seppänen, Mikko R J, Keskitalo, Salla, Virtanen, Anniina, Varjosalo, Markku, Silvennoinen, Olli, Isomäki, Pia
Published in Pharmaceuticals (Basel, Switzerland) (13.08.2021)
Published in Pharmaceuticals (Basel, Switzerland) (13.08.2021)
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