A Comparative Assessment Study of Known Small-Molecule Keap1−Nrf2 Protein–Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity
Tran, Kim T, Pallesen, Jakob S, Solbak, Sara M. Ø, Narayanan, Dilip, Baig, Amina, Zang, Jie, Aguayo-Orozco, Alejandro, Carmona, Rosa M. C, Garcia, Anthony D, Bach, Anders
Published in Journal of medicinal chemistry (12.09.2019)
Published in Journal of medicinal chemistry (12.09.2019)
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Non-covalent Small-Molecule Kelch-like ECH-Associated Protein 1–Nuclear Factor Erythroid 2‑Related Factor 2 (Keap1–Nrf2) Inhibitors and Their Potential for Targeting Central Nervous System Diseases
Pallesen, Jakob S, Tran, Kim T, Bach, Anders
Published in Journal of medicinal chemistry (27.09.2018)
Published in Journal of medicinal chemistry (27.09.2018)
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Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery
Narayanan, Dilip, Tran, Kim T., Pallesen, Jakob S., Solbak, Sara M. Ø., Qin, Yuting, Mukminova, Elina, Luchini, Martina, Vasilyeva, Kristina O., González Chichón, Dorleta, Goutsiou, Georgia, Poulsen, Cecilie, Haapanen, Nanna, Popowicz, Grzegorz M., Sattler, Michael, Olagnier, David, Gajhede, Michael, Bach, Anders
Published in Journal of medicinal chemistry (10.11.2022)
Published in Journal of medicinal chemistry (10.11.2022)
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N‑Biphenyl Pyrrolinones and Dibenzofurans as RNA-Binding Protein LIN28 Inhibitors Disrupting the LIN28–Let‑7 Interaction
Borgelt, Lydia, Hohnen, Lisa, Pallesen, Jakob S., Hommen, Pascal, Goebel, Georg L., Bosica, Francesco, Liu, Yang, O’Mahony, Gavin, Wu, Peng
Published in ACS medicinal chemistry letters (14.12.2023)
Published in ACS medicinal chemistry letters (14.12.2023)
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Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds
Pallesen, Jakob S, Narayanan, Dilip, Tran, Kim T, Solbak, Sara M. Ø, Marseglia, Giuseppe, Sørensen, Louis M. E, Høj, Lars J, Munafò, Federico, Carmona, Rosa M. C, Garcia, Anthony D, Desu, Haritha L, Brambilla, Roberta, Johansen, Tommy N, Popowicz, Grzegorz M, Sattler, Michael, Gajhede, Michael, Bach, Anders
Published in Journal of medicinal chemistry (22.04.2021)
Published in Journal of medicinal chemistry (22.04.2021)
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Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3‑3 Protein–Protein Interaction
Pallesen, Jakob S., Munier, Claire C., Bosica, Francesco, Andrei, Sebastian A., Edman, Karl, Gunnarsson, Anders, La Sala, Giuseppina, Putra, Okky Dwichandra, Srdanović, Sonja, Wilson, Andrew J., Wissler, Lisa, Ottmann, Christian, Perry, Matthew W. D., O’Mahony, Gavin
Published in Journal of medicinal chemistry (22.12.2022)
Published in Journal of medicinal chemistry (22.12.2022)
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Correction to “Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3‑3 Protein–Protein Interaction”
Pallesen, Jakob S., Munier, Claire C., Bosica, Francesco, Andrei, Sebastian A., Edman, Karl, Gunnarsson, Anders, La Sala, Giuseppina, Putra, Okky Dwichandra, Srdanović, Sonja, Wilson, Andrew J., Wissler, Lisa, Ottmann, Christian, Perry, Matthew W. D., O’Mahony, Gavin
Published in Journal of medicinal chemistry (09.02.2023)
Published in Journal of medicinal chemistry (09.02.2023)
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