Sensitizing Protective Tumor Microenvironments to Antibody-Mediated Therapy
Pallasch, Christian P., Leskov, Ilya, Braun, Christian J., Vorholt, Daniela, Drake, Adam, Soto-Feliciano, Yadira M., Bent, Eric H., Schwamb, Janine, Iliopoulou, Bettina, Kutsch, Nadine, van Rooijen, Nico, Frenzel, Lukas P., Wendtner, Clemens M., Heukamp, Lukas, Kreuzer, Karl Anton, Hallek, Michael, Chen, Jianzhu, Hemann, Michael T.
Published in Cell (30.01.2014)
Published in Cell (30.01.2014)
Get full text
Journal Article
Transcriptomic profiles and 5-year results from the randomized CLL14 study of venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab in chronic lymphocytic leukemia
Al-Sawaf, Othman, Zhang, Can, Jin, Hyun Yong, Robrecht, Sandra, Choi, Yoonha, Balasubramanian, Sandhya, Kotak, Alex, Chang, Yi Meng, Fink, Anna Maria, Tausch, Eugen, Schneider, Christof, Ritgen, Matthias, Kreuzer, Karl-Anton, Chyla, Brenda, Paulson, Joseph N., Pallasch, Christian P., Frenzel, Lukas P., Peifer, Martin, Eichhorst, Barbara, Stilgenbauer, Stephan, Jiang, Yanwen, Hallek, Michael, Fischer, Kirsten
Published in Nature communications (18.04.2023)
Published in Nature communications (18.04.2023)
Get full text
Journal Article
Author Correction: Transcriptomic profiles and 5-year results from the randomized CLL14 study of venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab in chronic lymphocytic leukemia
Al-Sawaf, Othman, Zhang, Can, Jin, Hyun Yong, Robrecht, Sandra, Choi, Yoonha, Balasubramanian, Sandhya, Kotak, Alex, Chang, Yi Meng, Fink, Anna Maria, Tausch, Eugen, Schneider, Christof, Ritgen, Matthias, Kreuzer, Karl-Anton, Chyla, Brenda, Paulson, Joseph N., Pallasch, Christian P., Frenzel, Lukas P., Peifer, Martin, Eichhorst, Barbara, Stilgenbauer, Stephan, Jiang, Yanwen, Hallek, Michael, Fischer, Kirsten
Published in Nature communications (23.10.2023)
Published in Nature communications (23.10.2023)
Get full text
Journal Article
Functional impact and molecular binding modes of drugs that target the PI3K isoform p110δ
Hassenrück, Floyd, Farina-Morillas, Maria, Neumann, Lars, Landini, Francesco, Blakemore, Stuart James, Rabipour, Mina, Alvarez-Idaboy, Juan Raul, Pallasch, Christian P., Hallek, Michael, Rebollido-Rios, Rocio, Krause, Günter
Published in Communications biology (05.06.2023)
Published in Communications biology (05.06.2023)
Get full text
Journal Article
A DNA/HDAC dual‐targeting drug CY190602 with significantly enhanced anticancer potency
Liu, Chuan, Ding, Hongyu, Li, Xiaoxi, Pallasch, Christian P, Hong, Liya, Guo, Dianwu, Chen, Yi, Wang, Difei, Wang, Wei, Wang, Yajie, Hemann, Michael T, Jiang, Hai
Published in EMBO molecular medicine (01.04.2015)
Published in EMBO molecular medicine (01.04.2015)
Get full text
Journal Article
Active Akt signaling triggers CLL toward Richter transformation via overactivation of Notch1
Kohlhaas, Vivien, Blakemore, Stuart James, Al-Maarri, Mona, Nickel, Nadine, Pal, Martin, Roth, Andreas, Hövelmeyer, Nadine, Schäfer, Stephan C., Knittel, Gero, Lohneis, Philipp, Nikolic, Milos, Wiederstein, Janica L., Franitza, Marek, Georgomonolis, Theodoros, Reinart, Nina, Herling, Marco, Herling, Carmen, Hartmann, Elena M., Rosenwald, Andreas, Klapper, Wolfram, Büttner, Reinhard, Moia, Riccardo, Rossi, Davide, Boldorini, Renzo, Gaidano, Gianluca, Frenzel, Lukas P., Reinhardt, Hans Christian, Brüning, Jens C., Hallek, Michael, Krüger, Marcus, Peifer, Martin, Pallasch, Christian P., Wunderlich, F. Thomas
Published in Blood (04.02.2021)
Published in Blood (04.02.2021)
Get full text
Journal Article
Extracellular vesicles and PD-L1 suppress macrophages inducing therapy resistance in TP53-deficient B-cell malignancies
Izquierdo, Elena, Vorholt, Daniela, Blakemore, Stuart, Sackey, Benedict, Nolte, Janica L., Barbarino, Verena, Schmitz, Jan, Nickel, Nadine, Bachurski, Daniel, Lobastova, Liudmila, Nikolic, Milos, Michalik, Michael, Brinker, Reinhild, Merkel, Olaf, Franitza, Marek, Georgomanolis, Theodoros, Neuhaus, René, Koch, Maximilian, Nasada, Niklas, Knittel, Gero, Chapuy, Björn, Ludwig, Nicole, Meese, Eckart, Frenzel, Lukas, Reinhardt, Hans Christian, Peifer, Martin, Rebollido-Rios, Rocio, Bruns, Heiko, Krüger, Marcus, Hallek, Michael, Pallasch, Christian
Published in Blood (23.06.2022)
Published in Blood (23.06.2022)
Get full text
Journal Article
Myeloperoxidase is a critical mediator of anthracycline-induced cardiomyopathy
Nettersheim, Felix Sebastian, Schlüter, Johannes David, Kreuzberg, Wiebke, Mehrkens, Dennis, Grimm, Simon, Nemade, Harshal, Braumann, Simon, Hof, Alexander, Guthoff, Henning, Peters, Vera, Hoyer, Friedrich Felix, Kargapolova, Yulia, Lackmann, Jan-Wilm, Müller, Stefan, Pallasch, Christian P., Hallek, Michael, Sachinidis, Agapios, Adam, Matti, Winkels, Holger, Baldus, Stephan, Geißen, Simon, Mollenhauer, Martin
Published in Basic research in cardiology (01.09.2023)
Published in Basic research in cardiology (01.09.2023)
Get full text
Journal Article
Rewired NFκB signaling as a potentially actionable feature of activated B-cell-like diffuse large B-cell lymphoma
Knittel, Gero, Liedgens, Paul, Korovkina, Darya, Pallasch, Christian P., Reinhardt, Hans Christian
Published in European journal of haematology (01.12.2016)
Published in European journal of haematology (01.12.2016)
Get full text
Journal Article
Kinase activity profiling reveals contribution of G-protein signaling modulator 2 deficiency to impaired regulatory T cell migration in rheumatoid arthritis
Meyer, Anja, Yan, Shuaifeng, Golumba-Nagy, Viktoria, Esser, Ruth L., Barbarino, Verena, Blakemore, Stuart J., Rusyn, Lisa, Nikiforov, Anastasia, Seeger-Nukpezah, Tamina, Grüll, Holger, Pallasch, Christian P., Kofler, David M.
Published in Journal of autoimmunity (01.11.2021)
Published in Journal of autoimmunity (01.11.2021)
Get full text
Journal Article
Lenalidomide enhances MOR202-dependent macrophage-mediated effector functions via the vitamin D pathway
Busch, Leonhard, Mougiakakos, Dimitrios, Büttner-Herold, Maike, Müller, Miriam J., Volmer, Dietrich A., Bach, Christian, Fabri, Mario, Bittenbring, Jörg T., Neumann, Frank, Boxhammer, Rainer, Nolting, Jens, Bisht, Savita, Böttcher, Martin, Jitschin, Simon, Hoffmann, Markus H., Balzer, Heidi, Beier, Fabian, Gezer, Deniz, Dudziak, Diana, Gelse, Kolja, Hennig, Friedrich F., Pallasch, Christian P., Spriewald, Bernd, Mackensen, Andreas, Bruns, Heiko
Published in Leukemia (01.11.2018)
Published in Leukemia (01.11.2018)
Get full text
Journal Article
miRs-138 and -424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in CLL
Berg, Valeska, Rusch, Marion, Vartak, Nachiket, Jüngst, Christian, Schauss, Astrid, Waldmann, Herbert, Hedberg, Christian, Pallasch, Christian P., Bastiaens, Philippe I.H., Hallek, Michael, Wendtner, Clemens-Martin, Frenzel, Lukas P.
Published in Blood (07.05.2015)
Published in Blood (07.05.2015)
Get full text
Journal Article
Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents
Lossos, Chen, Liu, Yunpeng, Kolb, Kellie E, Christie, Amanda L, Van Scoyk, Alexandria, Prakadan, Sanjay M, Shigemori, Kay, Stevenson, Kristen E, Morrow, Sara, Plana, Olivia D, Fraser, Cameron, Jones, Kristen L, Liu, Huiyun, Pallasch, Christian P, Modiste, Rebecca, Nguyen, Quang-De, Craig, Jeffrey W, Morgan, Elizabeth A, Vega, Francisco, Aster, Jon C, Sarosiek, Kristopher A, Shalek, Alex K, Hemann, Michael T, Weinstock, David M
Published in Cancer discovery (01.07.2019)
Published in Cancer discovery (01.07.2019)
Get full text
Journal Article
The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVH genes
Veldurthy, Aditya, Patz, Michaela, Hagist, Susanne, Pallasch, Christian P., Wendtner, Clemens-Martin, Hallek, Michael, Krause, Günter
Published in Blood (15.08.2008)
Published in Blood (15.08.2008)
Get full text
Journal Article
B-cell receptor triggers drug sensitivity of primary CLL cells by controlling glucosylation of ceramides
Schwamb, Janine, Feldhaus, Valeska, Baumann, Michael, Patz, Michaela, Brodesser, Susanne, Brinker, Reinhild, Claasen, Julia, Pallasch, Christian P., Hallek, Michael, Wendtner, Clemens-Martin, Frenzel, Lukas P.
Published in Blood (08.11.2012)
Published in Blood (08.11.2012)
Get full text
Journal Article
Detection of a novel truncating Merkel cell polyomavirus large T antigen deletion in chronic lymphocytic leukemia cells
Pantulu, N. Deepa, Pallasch, Christian P., Kurz, Anna Kordelia, Kassem, Ahmad, Frenzel, Lukas, Sodenkamp, Sebastian, Kvasnicka, Hans Michael, Wendtner, Clemens M., zur Hausen, Axel
Published in Blood (09.12.2010)
Published in Blood (09.12.2010)
Get full text
Journal Article