α-Helical peptidic scaffolds to target α-synuclein toxic species with nanomolar affinity
Santos, Jaime, Gracia, Pablo, Navarro, Susanna, Peña-Díaz, Samuel, Pujols, Jordi, Cremades, Nunilo, Pallarès, Irantzu, Ventura, Salvador
Published in Nature communications (18.06.2021)
Published in Nature communications (18.06.2021)
Get full text
Journal Article
Is a cure for Parkinson’s disease hiding inside us?
Santos, Jaime, Pallarès, Irantzu, Ventura, Salvador
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.08.2022)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.08.2022)
Get full text
Journal Article
Chemical Chaperones as Novel Drugs for Parkinson’s Disease
Pujols, Jordi, Peña-Díaz, Samuel, Pallarès, Irantzu, Ventura, Salvador
Published in Trends in molecular medicine (01.04.2020)
Published in Trends in molecular medicine (01.04.2020)
Get full text
Journal Article
Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis
Pinheiro, Francisca, Varejão, Nathalia, Esperante, Sebastian, Santos, Jaime, Velázquez‐Campoy, Adrián, Reverter, David, Pallarès, Irantzu, Ventura, Salvador
Published in The FEBS journal (01.01.2021)
Published in The FEBS journal (01.01.2021)
Get full text
Journal Article
Computational prediction of protein aggregation: Advances in proteomics, conformation-specific algorithms and biotechnological applications
Santos, Jaime, Pujols, Jordi, Pallarès, Irantzu, Iglesias, Valentín, Ventura, Salvador
Published in Computational and structural biotechnology journal (01.01.2020)
Published in Computational and structural biotechnology journal (01.01.2020)
Get full text
Journal Article
A Targetable N‑Terminal Motif Orchestrates α‑Synuclein Oligomer-to-Fibril Conversion
Santos, Jaime, Cuellar, Jorge, Pallarès, Irantzu, Byrd, Emily J., Lends, Alons, Moro, Fernando, Abdul-Shukkoor, Muhammed Bilal, Pujols, Jordi, Velasco-Carneros, Lorea, Sobott, Frank, Otzen, Daniel E., Calabrese, Antonio N., Muga, Arturo, Pedersen, Jan Skov, Loquet, Antoine, Valpuesta, Jose María, Radford, Sheena E., Ventura, Salvador
Published in Journal of the American Chemical Society (08.05.2024)
Published in Journal of the American Chemical Society (08.05.2024)
Get full text
Journal Article
Development of a Highly Potent Transthyretin Amyloidogenesis Inhibitor: Design, Synthesis, and Evaluation
Pinheiro, Francisca, Pallarès, Irantzu, Peccati, Francesca, Sánchez-Morales, Adrià, Varejão, Nathalia, Bezerra, Filipa, Ortega-Alarcon, David, Gonzalez, Danilo, Osorio, Marcelo, Navarro, Susanna, Velázquez-Campoy, Adrián, Almeida, Maria Rosário, Reverter, David, Busqué, Félix, Alibés, Ramon, Sodupe, Mariona, Ventura, Salvador
Published in Journal of medicinal chemistry (10.11.2022)
Published in Journal of medicinal chemistry (10.11.2022)
Get full text
Journal Article
Prion‐like proteins: from computational approaches to proteome‐wide analysis
Gil‐Garcia, Marcos, Iglesias, Valentín, Pallarès, Irantzu, Ventura, Salvador
Published in FEBS open bio (01.09.2021)
Published in FEBS open bio (01.09.2021)
Get full text
Journal Article
An α-helical peptide-based plasmonic biosensor for highly specific detection of α-synuclein toxic oligomers
Giarola, Juliana Fátima, Santos, Jaime, Estevez, M.-Carmen, Ventura, Salvador, Pallarès, Irantzu, Lechuga, Laura M.
Published in Analytica chimica acta (22.05.2024)
Published in Analytica chimica acta (22.05.2024)
Get full text
Journal Article
Discovering Putative Prion-Like Proteins in Plasmodium falciparum : A Computational and Experimental Analysis
Pallarès, Irantzu, de Groot, Natalia S, Iglesias, Valentín, Sant'Anna, Ricardo, Biosca, Arnau, Fernàndez-Busquets, Xavier, Ventura, Salvador
Published in Frontiers in microbiology (07.08.2018)
Published in Frontiers in microbiology (07.08.2018)
Get full text
Journal Article
pH-Dependent Aggregation in Intrinsically Disordered Proteins Is Determined by Charge and Lipophilicity
Santos, Jaime, Iglesias, Valentín, Santos-Suárez, Juan, Mangiagalli, Marco, Brocca, Stefania, Pallarès, Irantzu, Ventura, Salvador
Published in Cells (Basel, Switzerland) (08.01.2020)
Published in Cells (Basel, Switzerland) (08.01.2020)
Get full text
Journal Article
PITB: A high affinity transthyretin aggregation inhibitor with optimal pharmacokinetic properties
Pinheiro, Francisca, Varejão, Nathalia, Sánchez-Morales, Adrià, Bezerra, Filipa, Navarro, Susanna, Velázquez-Campoy, Adrián, Busqué, Félix, Almeida, Maria Rosário, Alibés, Ramon, Reverter, David, Pallarès, Irantzu, Ventura, Salvador
Published in European journal of medicinal chemistry (05.12.2023)
Published in European journal of medicinal chemistry (05.12.2023)
Get full text
Journal Article