Multiple cationic amphiphiles induce a Niemann-Pick C phenotype and inhibit Ebola virus entry and infection
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Published in PloS one (18.02.2013)
Published in PloS one (18.02.2013)
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A novel slow-inactivation-specific ion channel modulator attenuates neuropathic pain
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Published in Pain (Amsterdam) (01.04.2011)
Published in Pain (Amsterdam) (01.04.2011)
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Structure–activity relationships of diphenylpiperazine N-type calcium channel inhibitors
Pajouhesh, Hassan, Feng, Zhong-Ping, Ding, Yanbing, Zhang, Lingyun, Pajouhesh, Hossein, Morrison, Jerrie-Lynn, Belardetti, Francesco, Tringham, Elizabeth, Simonson, Eric, Vanderah, Todd W., Porreca, Frank, Zamponi, Gerald W., Mitscher, Lester A., Snutch, Terrance P.
Published in Bioorganic & medicinal chemistry letters (15.02.2010)
Published in Bioorganic & medicinal chemistry letters (15.02.2010)
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Correction: Multiple Cationic Amphiphiles Induce a Niemann-Pick C Phenotype and Inhibit Ebola Virus Entry and Infection
Shoemaker, Charles J., Schornberg, Kathryn L., Delos, Sue E., Scully, Corinne, Pajouhesh, Hassan, Olinger, Gene G., Johansen, Lisa M., White, Judith M.
Published in PloS one (01.10.2013)
Published in PloS one (01.10.2013)
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A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity
Johansen, Lisa M, DeWald, Lisa Evans, Shoemaker, Charles J, Hoffstrom, Benjamin G, Lear-Rooney, Calli M, Stossel, Andrea, Nelson, Elizabeth, Delos, Sue E, Simmons, James A, Grenier, Jill M, Pierce, Laura T, Pajouhesh, Hassan, Lehár, Joseph, Hensley, Lisa E, Glass, Pamela J, White, Judith M, Olinger, Gene G
Published in Science translational medicine (03.06.2015)
Published in Science translational medicine (03.06.2015)
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ST-2560, a selective inhibitor of the Na V 1.7 sodium channel, affects nocifensive and cardiovascular reflexes in non-human primates
Mulcahy, John V, Beckley, Jacob T, Klas, Sheri D, Odink, Debra A, Delwig, Anton, Pajouhesh, Hassan, Monteleone, Dennis, Zhou, Xiang, Du Bois, Justin, Yeomans, David C, Luu, George, Hunter, John C
Published in British journal of pharmacology (01.09.2024)
Published in British journal of pharmacology (01.09.2024)
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Discovery of Selective Inhibitors of Na V 1.7 Templated on Saxitoxin as Therapeutics for Pain
Pajouhesh, Hassan, Delwig, Anton, Beckley, Jacob T., Klas, Sheri, Monteleone, Dennis, Zhou, Xiang, Luu, George, Du Bois, J., Hunter, John C., Mulcahy, John V.
Published in ACS medicinal chemistry letters (10.11.2022)
Published in ACS medicinal chemistry letters (10.11.2022)
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Journal Article
Discovery of Selective Inhibitors of NaV1.7 Templated on Saxitoxin as Therapeutics for Pain
Pajouhesh, Hassan, Delwig, Anton, Beckley, Jacob T., Klas, Sheri, Monteleone, Dennis, Zhou, Xiang, Luu, George, Du Bois, J., Hunter, John C., Mulcahy, John V.
Published in ACS medicinal chemistry letters (10.11.2022)
Published in ACS medicinal chemistry letters (10.11.2022)
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Antinociceptive properties of an isoform-selective inhibitor of Nav1.7 derived from saxitoxin in mouse models of pain
Beckley, Jacob T, Pajouhesh, Hassan, Luu, George, Klas, Sheri, Delwig, Anton, Monteleone, Dennis, Zhou, Xiang, Giuvelis, Denise, Meng, Ian D, Yeomans, David C, Hunter, John C, Mulcahy, John V
Published in Pain (Amsterdam) (01.04.2021)
Published in Pain (Amsterdam) (01.04.2021)
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T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures
Tringham, Elizabeth, Powell, Kim L, Cain, Stuart M, Kuplast, Kristy, Mezeyova, Janette, Weerapura, Manjula, Eduljee, Cyrus, Jiang, Xinpo, Smith, Paula, Morrison, Jerrie-Lynn, Jones, Nigel C, Braine, Emma, Rind, Gil, Fee-Maki, Molly, Parker, David, Pajouhesh, Hassan, Parmar, Manjeet, O'Brien, Terence J, Snutch, Terrance P
Published in Science translational medicine (15.02.2012)
Published in Science translational medicine (15.02.2012)
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Modular, efficient synthesis of asymmetrically substituted piperazine scaffolds as potent calcium channel blockers
Borzenko, Andrey, Pajouhesh, Hassan, Morrison, Jerrie-Lynn, Tringham, Elizabeth, Snutch, Terrance P., Schafer, Laurel L.
Published in Bioorganic & medicinal chemistry letters (01.06.2013)
Published in Bioorganic & medicinal chemistry letters (01.06.2013)
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Scaffold-based design and synthesis of potent N-type calcium channel blockers
Zamponi, Gerald W., Feng, Zhong-Ping, Zhang, Lingyun, Pajouhesh, Hossein, Ding, Yanbing, Belardetti, Francesco, Pajouhesh, Hassan, Dolphin, David, Mitscher, Lester A., Snutch, Terrance P.
Published in Bioorganic & medicinal chemistry letters (15.11.2009)
Published in Bioorganic & medicinal chemistry letters (15.11.2009)
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Year of Publication 05.02.2020
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Year of Publication 05.02.2020
Patent
Structure–activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitors
Pajouhesh, Hassan, Feng, Zhong-Ping, Zhang, Lingyun, Pajouhesh, Hossein, Jiang, Xinpo, Hendricson, Adam, Dong, Haiheng, Tringham, Elizabeth, Ding, Yanbing, Vanderah, Todd W., Porreca, Frank, Belardetti, Francesco, Zamponi, Gerald W., Mitscher, Lester A., Snutch, Terrance P.
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
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N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS
CHAKKA NAGASREE, TAN JASON, KAUL RAMESH, ZHOU YUANXI, DING YANBING, GRIMWOOD MIKE, PAJOUHESH HASSAN, ZHU YONGBAO, ZHANG LINGYUN
Year of Publication 22.10.2018
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Year of Publication 22.10.2018
Patent