Hydrostatic pressure regulates CYP1A2 expression in human hepatocytes via a mechanosensitive aryl hydrocarbon receptor-dependent pathway
Burton, Lewis, Scaife, Paula, Paine, Stuart W, Mellor, Howard R, Abernethy, Lynn, Littlewood, Peter, Rauch, Cyril
Published in American Journal of Physiology: Cell Physiology (01.05.2020)
Published in American Journal of Physiology: Cell Physiology (01.05.2020)
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Prediction of the Pharmacokinetics of Atorvastatin, Cerivastatin, and Indomethacin Using Kinetic Models Applied to Isolated Rat Hepatocytes
PAINE, Stuart W, PARKER, Alison J, GARDINER, Philip, WEBBORN, Peter J. H, RILEY, Robert J
Published in Drug metabolism and disposition (01.07.2008)
Published in Drug metabolism and disposition (01.07.2008)
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Journal Article
From ATP to AZD6140 : The discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis
SPRINGTHORPE, Brian, BAILEY, Andrew, HUNT, Simon F, INCE, Francis, INGALL, Anthony H, KIRK, Ian P, LEESON, Paul D, LEFF, Paul, LEWIS, Richard J, MARTIN, Barrie P, MCGINNITY, Dermot F, MORTIMORE, Michael P, BARTON, Patrick, PAINE, Stuart W, PAIRAUDEAU, Garry, PATEL, Anil, RIGBY, Aaron J, RILEY, Robert J, TEOBALD, Barry J, TOMLINSON, Wendy, WEBBORN, Peter J. H, WILLIS, Paul A, BIRKINSHAW, Timothy N, BONNERT, Roger V, BROWN, Roger C, CHAPMAN, David, DIXON, John, GUILE, Simon D, HUMPHRIES, Robert G
Published in Bioorganic & medicinal chemistry letters (01.11.2007)
Published in Bioorganic & medicinal chemistry letters (01.11.2007)
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Journal Article
Generation of in-silico cytochrome P450 1A2, 2C9, 2C19, 2D6, and 3A4 inhibition QSAR models
Gleeson, M Paul, Davis, Andrew M, Chohan, Kamaldeep K, Paine, Stuart W, Boyer, Scott, Gavaghan, Claire L, Arnby, Catrin Hasselgren, Kankkonen, Cecilia, Albertson, Nan
Published in Journal of computer-aided molecular design (01.10.2007)
Published in Journal of computer-aided molecular design (01.10.2007)
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Evaluation of the solubility of a range of copper sources and the effects of iron & sulphur on copper solubility under rumen simulated conditions
Clarkson, Andrea H., Paine, Stuart W., Kendall, Nigel R.
Published in Journal of trace elements in medicine and biology (01.12.2021)
Published in Journal of trace elements in medicine and biology (01.12.2021)
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Journal Article
Prediction of Human Renal Clearance from Preclinical Species for a Diverse Set of Drugs That Exhibit Both Active Secretion and Net Reabsorption
PAINE, Stuart W, MENOCHET, Karelle, DENTON, Rebecca, MCGINNITY, Dermot F, RILEY, Robert J
Published in Drug metabolism and disposition (01.06.2011)
Published in Drug metabolism and disposition (01.06.2011)
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Journal Article
Novel holistic pharmacokinetic model applied to plasma and urine concentrations of 2,5-dihydroxybenzene sulphonate following administrations of calcium dobesilate and etamsylate to exercised horses
Paine, Stuart W, Harding, Caitlin, Waller, Christopher C, Zemenova, Jana, Viljanto, Marjaana, Habershon Butcher, Jocelyn, Hincks, Pamela R
Published in Journal of veterinary pharmacology and therapeutics (01.11.2023)
Published in Journal of veterinary pharmacology and therapeutics (01.11.2023)
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Journal Article
Can long range mechanical interaction between drugs and membrane proteins define the notion of molecular promiscuity? Application to P-glycoprotein-mediated multidrug resistance (MDR)
Rauch, Cyril, Paine, Stuart W., Littlewood, Peter
Published in Biochimica et biophysica acta (01.11.2013)
Published in Biochimica et biophysica acta (01.11.2013)
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Journal Article
Plasma and urine pharmacokinetics of hydroxyzine and cetirizine following repeated oral administrations to exercised horses
Paine, Stuart W., Aldurdunji, Mohammed, Garth‐Greeves, Alix, Muir, Tessa, Hincks, Pamela R.
Published in Journal of veterinary pharmacology and therapeutics (01.01.2022)
Published in Journal of veterinary pharmacology and therapeutics (01.01.2022)
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Journal Article
Re‐evaluation of the pharmacokinetics of xylazine administered to Thoroughbred horses
Habershon‐Butcher, Jocelyn, Cutler, Charlotte, Viljanto, Marjaana, Hincks, Pamela R., Biddle, Simon, Paine, Stuart W.
Published in Journal of veterinary pharmacology and therapeutics (01.01.2020)
Published in Journal of veterinary pharmacology and therapeutics (01.01.2020)
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Journal Article
The intravenous pharmacokinetics of butorphanol and detomidine dosed in combination compared with individual dose administrations to exercised horses
Paine, Stuart W., Bright, Jane, Scarth, James P., Hincks, Pamela R., Pearce, Clive M., Hannan, Colette, Machnik, Marc, Hillyer, Lynn
Published in Journal of veterinary pharmacology and therapeutics (01.03.2020)
Published in Journal of veterinary pharmacology and therapeutics (01.03.2020)
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Journal Article
The effects of aging on hepatic microsomal scaling factor and hepatocellularity number in the horse
Shibany, Khaled A., Tötemeyer, Sabine, Pratt, Stefanie L., Paine, Stuart W.
Published in Xenobiotica (02.12.2018)
Published in Xenobiotica (02.12.2018)
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