Identification and validation of a gene causing cross-resistance between insecticide classes in Anopheles gambiae from Ghana
Mitchell, Sara N, Stevenson, Bradley J, Müller, Pie, Wilding, Craig S, Egyir-Yawson, Alexander, Field, Stuart G, Hemingway, Janet, Paine, Mark J. I, Ranson, Hilary, Donnelly, Martin James
Published in Proceedings of the National Academy of Sciences - PNAS (17.04.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (17.04.2012)
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CYP6 P450 enzymes and ACE-1 duplication produce extreme and multiple insecticide resistance in the malaria mosquito Anopheles gambiae
Edi, Constant V, Djogbénou, Luc, Jenkins, Adam M, Regna, Kimberly, Muskavitch, Marc A T, Poupardin, Rodolphe, Jones, Christopher M, Essandoh, John, Kétoh, Guillaume K, Paine, Mark J I, Koudou, Benjamin G, Donnelly, Martin J, Ranson, Hilary, Weetman, David
Published in PLoS genetics (01.03.2014)
Published in PLoS genetics (01.03.2014)
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Chlorfenapyr metabolism by mosquito P450s associated with pyrethroid resistance identifies potential activation markers
Yunta, Cristina, Ooi, Jocelyn M. F., Oladepo, Folasade, Grafanaki, Sofia, Pergantis, Spiros. A., Tsakireli, Dimitra, Ismail, Hanafy M., Paine, Mark J. I.
Published in Scientific reports (29.08.2023)
Published in Scientific reports (29.08.2023)
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Tandem duplication of a genomic region encoding glutathione S-transferase epsilon-2 and -4 genes in DDT-resistant Anopheles stephensi strain from India
Dykes, Cherry L., Sharma, Gunjan, Behera, Abhisek K., Kapoor, Neera, Paine, Mark J. I., Donnelly, Martin J., Singh, Om P.
Published in Scientific reports (25.10.2022)
Published in Scientific reports (25.10.2022)
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A high-throughput HPLC method for simultaneous quantification of pyrethroid and pyriproxyfen in long-lasting insecticide-treated nets
Walker, Kyle J., Williams, Christopher T., Oladepo, Folasade O., Lucas, John, Malone, David, Paine, Mark J. I., Ismail, Hanafy M.
Published in Scientific reports (11.06.2022)
Published in Scientific reports (11.06.2022)
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Author Correction: Chlorfenapyr metabolism by mosquito P450s associated with pyrethroid resistance identifies potential activation markers
Yunta, Cristina, Ooi, Jocelyn M. F., Oladepo, Folasade, Grafanaki, Sofia, Pergantis, Spiros. A., Tsakireli, Dimitra, Ismail, Hanafy M., Paine, Mark J. I.
Published in Scientific reports (16.11.2023)
Published in Scientific reports (16.11.2023)
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Author Correction: New insecticide screening platforms indicate that Mitochondrial Complex I inhibitors are susceptible to cross-resistance by mosquito P450s that metabolise pyrethroids
Lees, Rosemary S, Ismail, Hanafy M, Logan, Rhiannon A E, Malone, David, Davies, Rachel, Anthousi, Amalia, Adolfi, Adriana, Lycett, Gareth J, Paine, Mark J I
Published in Scientific reports (06.10.2023)
Published in Scientific reports (06.10.2023)
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Metabolic and target-site mechanisms combine to confer strong DDT resistance in Anopheles gambiae
Mitchell, Sara N, Rigden, Daniel J, Dowd, Andrew J, Lu, Fang, Wilding, Craig S, Weetman, David, Dadzie, Samuel, Jenkins, Adam M, Regna, Kimberly, Boko, Pelagie, Djogbenou, Luc, Muskavitch, Marc A T, Ranson, Hilary, Paine, Mark J I, Mayans, Olga, Donnelly, Martin J
Published in PloS one (27.03.2014)
Published in PloS one (27.03.2014)
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High pyrethroid/DDT resistance in major malaria vector Anopheles coluzzii from Niger-Delta of Nigeria is probably driven by metabolic resistance mechanisms
Muhammad, Abdullahi, Ibrahim, Sulaiman S, Mukhtar, Muhammad M, Irving, Helen, Abajue, Maduamaka C, Edith, Noutcha M A, Da'u, Sabitu S, Paine, Mark J I, Wondji, Charles S
Published in PloS one (11.03.2021)
Published in PloS one (11.03.2021)
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Pinpointing P450s associated with pyrethroid metabolism in the dengue vector, Aedes aegypti: developing new tools to combat insecticide resistance
Stevenson, Bradley J, Pignatelli, Patricia, Nikou, Dimitra, Paine, Mark J I
Published in PLoS neglected tropical diseases (01.03.2012)
Published in PLoS neglected tropical diseases (01.03.2012)
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Indoor residual spraying practices against Triatoma infestans in the Bolivian Chaco: contributing factors to suboptimal insecticide delivery to treated households
Gonçalves, Raquel, Logan, Rhiannon A E, Ismail, Hanafy M, Paine, Mark J I, Bern, Caryn, Courtenay, Orin
Published in Parasites & vectors (16.06.2021)
Published in Parasites & vectors (16.06.2021)
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Field-caught permethrin-resistant Anopheles gambiae overexpress CYP6P3, a P450 that metabolises pyrethroids
Müller, Pie, Warr, Emma, Stevenson, Bradley J, Pignatelli, Patricia M, Morgan, John C, Steven, Andrew, Yawson, Alexander E, Mitchell, Sara N, Ranson, Hilary, Hemingway, Janet, Paine, Mark J I, Donnelly, Martin J
Published in PLoS genetics (01.11.2008)
Published in PLoS genetics (01.11.2008)
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Improving the performance of spray operators through monitoring and evaluation of insecticide concentrations of pirimiphos-methyl during indoor residual spraying for malaria control on Bioko Island
Fuseini, Godwin, Ismail, Hanafy M, von Fricken, Michael E, Weppelmann, Thomas A, Smith, Jordan, Ellis Logan, Rhiannon Agnes, Oladepo, Folasade, Walker, Kyle J, Phiri, Wonder P, Paine, Mark J I, García, Guillermo A
Published in Malaria journal (21.01.2020)
Published in Malaria journal (21.01.2020)
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Development of a rapid field-applicable molecular diagnostic for knockdown resistance (kdr) markers in An. gambiae
Unwin, Vera T, Ainsworth, Shaun, Rippon, Emily J, Niang, El Hadji Amadou, Paine, Mark J I, Weetman, David, Adams, Emily R
Published in Parasites & vectors (18.05.2018)
Published in Parasites & vectors (18.05.2018)
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Antimalarial activity of primaquine operates via a two-step biochemical relay
Camarda, Grazia, Jirawatcharadech, Piyaporn, Priestley, Richard S., Saif, Ahmed, March, Sandra, Wong, Michael H. L., Leung, Suet, Miller, Alex B., Baker, David A., Alano, Pietro, Paine, Mark J. I., Bhatia, Sangeeta N., O’Neill, Paul M., Ward, Stephen A., Biagini, Giancarlo A.
Published in Nature communications (19.07.2019)
Published in Nature communications (19.07.2019)
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Directionally selected cytochrome P450 alleles are driving the spread of pyrethroid resistance in the major malaria vector Anopheles funestus
Riveron, Jacob M., Irving, Helen, Ndula, Miranda, Barnes, Kayla G., Ibrahim, Sulaiman S., Paine, Mark J. I., Wondji, Charles S.
Published in Proceedings of the National Academy of Sciences - PNAS (02.01.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (02.01.2013)
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Multiple Substrate Binding by Cytochrome P450 3A4: Estimation of the Number of Bound Substrate Molecules
KAPELYUKH, Yury, PAINE, Mark J. I, MARECHAL, Jean-Didier, SUTCLIFFE, Michael J, WOLF, C. Roland, ROBERTS, Gordon C. K
Published in Drug metabolism and disposition (01.10.2008)
Published in Drug metabolism and disposition (01.10.2008)
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