Multi‐target, ensemble‐based virtual screening yields novel allosteric KRAS inhibitors at high success rate
Gupta, Amit K., Wang, Xu, Pagba, Cynthia V., Prakash, Priyanka, Sarkar‐Banerjee, Suparna, Putkey, John, Gorfe, Alemayehu A.
Published in Chemical biology & drug design (01.08.2019)
Published in Chemical biology & drug design (01.08.2019)
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Journal Article
Tyrosine, cysteine, and proton coupled electron transfer in a ribonucleotide reductase-inspired beta hairpin maquette
McCaslin, Tyler G, Pagba, Cynthia V, Hwang, Hyea, Gumbart, James C, Chi, San-Hui, Perry, Joseph W, Barry, Bridgette A
Published in Chemical communications (Cambridge, England) (2019)
Published in Chemical communications (Cambridge, England) (2019)
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Journal Article
Discovery of High-Affinity Noncovalent Allosteric KRAS Inhibitors That Disrupt Effector Binding
McCarthy, Michael J, Pagba, Cynthia V, Prakash, Priyanka, Naji, Ali K, van der Hoeven, Dharini, Liang, Hong, Gupta, Amit K, Zhou, Yong, Cho, Kwang-Jin, Hancock, John F, Gorfe, Alemayehu A
Published in ACS omega (28.02.2019)
Published in ACS omega (28.02.2019)
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Journal Article
Directly probing redox-linked quinones in photosystem II membrane fragments via UV resonance Raman scattering
Chen, Jun, Yao, Mingdong, Pagba, Cynthia V., Zheng, Yang, Fei, Liping, Feng, Zhaochi, Barry, Bridgette A.
Published in Biochimica et biophysica acta (01.06.2015)
Published in Biochimica et biophysica acta (01.06.2015)
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Journal Article
Biophysical and Biochemical Characterization of Structurally Diverse Small Molecule Hits for KRAS Inhibition
Pagba, Cynthia V., Gupta, Amit K., Dilsha, Kasuni, Sadrpour, Parisa, Jakubec, Jacob, Prakash, Priyanka, Hoeven, Dharini, Cho, Kwang‐Jin, Gilbertson, Scott, Gorfe, Alemayehu A.
Published in Chembiochem : a European journal of chemical biology (02.04.2024)
Published in Chembiochem : a European journal of chemical biology (02.04.2024)
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Journal Article
A tyrosine–tryptophan dyad and radical-based charge transfer in a ribonucleotide reductase-inspired maquette
Pagba, Cynthia V., McCaslin, Tyler G., Veglia, Gianluigi, Porcelli, Fernando, Yohannan, Jiby, Guo, Zhanjun, McDaniel, Miranda, Barry, Bridgette A.
Published in Nature communications (02.12.2015)
Published in Nature communications (02.12.2015)
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Journal Article
Aptamer-Based SERRS Sensor for Thrombin Detection
Cho, Hansang, Baker, Brian R, Wachsmann-Hogiu, Sebastian, Pagba, Cynthia V, Laurence, Ted A, Lane, Stephen M, Lee, Luke P, Tok, Jeffrey B.-H
Published in Nano letters (01.12.2008)
Published in Nano letters (01.12.2008)
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Journal Article
Vibrational State Dependence of Interfacial Electron Transfer: Hot Electron Injection from the S1 State of Azulene into TiO2 Nanoparticles
Myahkostupov, Mykhaylo, Pagba, Cynthia V, Gundlach, Lars, Piotrowiak, Piotr
Published in Journal of physical chemistry. C (10.10.2013)
Published in Journal of physical chemistry. C (10.10.2013)
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Journal Article
Proton-Coupled Electron Transfer and a Tyrosine–Histidine Pair in a Photosystem II-Inspired β‑Hairpin Maquette: Kinetics on the Picosecond Time Scale
Pagba, Cynthia V, McCaslin, Tyler G, Chi, San-Hui, Perry, Joseph W, Barry, Bridgette A
Published in The journal of physical chemistry. B (25.02.2016)
Published in The journal of physical chemistry. B (25.02.2016)
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Journal Article
Redox-Driven Conformational Dynamics in a Photosystem-II-Inspired β‑Hairpin Maquette Determined through Spectroscopy and Simulation
Hwang, Hyea, McCaslin, Tyler G, Hazel, Anthony, Pagba, Cynthia V, Nevin, Christina M, Pavlova, Anna, Barry, Bridgette A, Gumbart, James C
Published in The journal of physical chemistry. B (20.04.2017)
Published in The journal of physical chemistry. B (20.04.2017)
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Journal Article
Structure and Function of Tryptophan–Tyrosine Dyads in Biomimetic β Hairpins
McCaslin, Tyler G, Pagba, Cynthia V, Chi, San-Hui, Hwang, Hyea J, Gumbart, James C, Perry, Joseph W, Olivieri, Cristina, Porcelli, Fernando, Veglia, Gianluigi, Guo, Zhanjun, McDaniel, Miranda, Barry, Bridgette A
Published in The journal of physical chemistry. B (04.04.2019)
Published in The journal of physical chemistry. B (04.04.2019)
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Journal Article
Direct detection of aptamer-thrombin binding via surface-enhanced Raman spectroscopy
Pagba, Cynthia V, Lane, Stephen M, Cho, Hansang, Wachsmann-Hogiu, Sebastian
Published in Journal of Biomedical Optics (01.07.2010)
Published in Journal of Biomedical Optics (01.07.2010)
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Journal Article
KRAS Inhibitor that Simultaneously Inhibits Nucleotide Exchange Activity and Effector Engagement
Pagba, Cynthia V., Gupta, Amit K., Naji, Ali K., van der Hoeven, Dharini, Churion, Kelly, Liang, Xiaowen, Jakubec, Jacob, Hook, Magnus, Zuo, Yan, Martinez de Kraatz, Marisela, Frost, Jeffrey A., Gorfe, Alemayehu A.
Published in ACS bio & med chem au (21.12.2022)
Published in ACS bio & med chem au (21.12.2022)
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