Dimensionality reduction reveals fine-scale structure in the Japanese population with consequences for polygenic risk prediction
Sakaue, Saori, Hirata, Jun, Kanai, Masahiro, Suzuki, Ken, Akiyama, Masato, Lai Too, Chun, Arayssi, Thurayya, Hammoudeh, Mohammed, Al Emadi, Samar, Masri, Basel K., Halabi, Hussein, Badsha, Humeira, Uthman, Imad W., Saxena, Richa, Padyukov, Leonid, Hirata, Makoto, Matsuda, Koichi, Murakami, Yoshinori, Kamatani, Yoichiro, Okada, Yukinori
Published in Nature communications (26.03.2020)
Published in Nature communications (26.03.2020)
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Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
Liu, Yun, Aryee, Martin J, Padyukov, Leonid, Fallin, M Daniele, Hesselberg, Espen, Runarsson, Arni, Reinius, Lovisa, Acevedo, Nathalie, Taub, Margaret, Ronninger, Marcus, Shchetynsky, Klementy, Scheynius, Annika, Kere, Juha, Alfredsson, Lars, Klareskog, Lars, Ekström, Tomas J, Feinberg, Andrew P
Published in Nature biotechnology (01.02.2013)
Published in Nature biotechnology (01.02.2013)
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Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
Raychaudhuri, Soumya, Sandor, Cynthia, Stahl, Eli A, Freudenberg, Jan, Lee, Hye-Soon, Jia, Xiaoming, Alfredsson, Lars, Padyukov, Leonid, Klareskog, Lars, Worthington, Jane, Siminovitch, Katherine A, Bae, Sang-Cheol, Plenge, Robert M, Gregersen, Peter K, de Bakker, Paul I W
Published in Nature genetics (01.03.2012)
Published in Nature genetics (01.03.2012)
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Journal Article
Immunity to citrullinated proteins in rheumatoid arthritis
Klareskog, Lars, Rönnelid, Johan, Lundberg, Karin, Padyukov, Leonid, Alfredsson, Lars
Published in Annual review of immunology (01.01.2008)
Published in Annual review of immunology (01.01.2008)
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Early prediction of clinical response to anti-TNF treatment using multi-omics and machine learning in rheumatoid arthritis
Yoosuf, Niyaz, Maciejewski, Mateusz, Ziemek, Daniel, Jelinsky, Scott A, Folkersen, Lasse, Müller, Malin, Sahlström, Peter, Vivar, Nancy, Catrina, Anca, Berg, Louise, Klareskog, Lars, Padyukov, Leonid, Brynedal, Boel
Published in Rheumatology (Oxford, England) (11.04.2022)
Published in Rheumatology (Oxford, England) (11.04.2022)
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Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile
Lundberg, Karin, Bengtsson, Camilla, Kharlamova, Nastya, Reed, Evan, Jiang, Xia, Kallberg, Henrik, Pollak-Dorocic, Iskra, Israelsson, Lena, Kessel, Christoph, Padyukov, Leonid, Holmdahl, Rikard, Alfredsson, Lars, Klareskog, Lars
Published in Annals of the rheumatic diseases (01.05.2013)
Published in Annals of the rheumatic diseases (01.05.2013)
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Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smoke
Källberg, Henrik, Ding, Bo, Padyukov, Leonid, Bengtsson, Camilla, Rönnelid, Johan, Klareskog, Lars, Alfredsson, Lars
Published in Annals of the rheumatic diseases (01.03.2011)
Published in Annals of the rheumatic diseases (01.03.2011)
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Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups
Rothwell, Simon, Cooper, Robert G, Lundberg, Ingrid E, Miller, Frederick W, Gregersen, Peter K, Bowes, John, Vencovsky, Jiri, Danko, Katalin, Limaye, Vidya, Selva-O'Callaghan, Albert, Hanna, Michael G, Machado, Pedro M, Pachman, Lauren M, Reed, Ann M, Rider, Lisa G, Cobb, Joanna, Platt, Hazel, Molberg, Øyvind, Benveniste, Olivier, Mathiesen, Pernille, Radstake, Timothy, Doria, Andrea, De Bleecker, Jan, De Paepe, Boel, Maurer, Britta, Ollier, William E, Padyukov, Leonid, O'Hanlon, Terrance P, Lee, Annette, Amos, Christopher I, Gieger, Christian, Meitinger, Thomas, Winkelmann, Juliane, Wedderburn, Lucy R, Chinoy, Hector, Lamb, Janine A
Published in Annals of the rheumatic diseases (01.08.2016)
Published in Annals of the rheumatic diseases (01.08.2016)
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A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
Graham, Robert R, Kosoy, Roman, Sun, Xin, Rantapää-Dahlqvist, Solbritt, Baechler, Emily C, Lee, Annette, Syvänen, Ann-Christine, Kimberly, Robert P, Behrens, Timothy W, Sturfelt, Gunnar, Criswell, Lindsey A, Gateva, Vesela, Edberg, Jeffrey C, Padyukov, Leonid, McGwin, Gerald, Ferreira, Ricardo C, Gunnarsson, Iva, Sandling, Johanna K, Bengtsson, Anders A, Hom, Geoff, Reveille, John D, Jönsen, Andreas, Gregersen, Peter K, Seldin, Michael F, Taylor, Kimberly E, Chung, Sharon A, Petri, Michelle A, Svenungsson, Elisabet, Vilá, Luis M, Rönnblom, Lars, Alarcón, Graciela S, Nordmark, Gunnel, Manzi, Susan, Brown, Elizabeth E, Ortmann, Ward, Ramsey-Goldman, Rosalind
Published in Nature genetics (01.11.2009)
Published in Nature genetics (01.11.2009)
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Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility
Yin, Xianyong, Low, Hui Qi, Wang, Ling, Li, Yonghong, Ellinghaus, Eva, Han, Jiali, Estivill, Xavier, Sun, Liangdan, Zuo, Xianbo, Shen, Changbing, Zhu, Caihong, Zhang, Anping, Sanchez, Fabio, Padyukov, Leonid, Catanese, Joseph J., Krueger, Gerald G., Duffin, Kristina Callis, Mucha, Sören, Weichenthal, Michael, Weidinger, Stephan, Lieb, Wolfgang, Foo, Jia Nee, Li, Yi, Sim, Karseng, Liany, Herty, Irwan, Ishak, Teo, Yikying, Theng, Colin T. S., Gupta, Rashmi, Bowcock, Anne, De Jager, Philip L., Qureshi, Abrar A., de Bakker, Paul I. W., Seielstad, Mark, Liao, Wilson, Ståhle, Mona, Franke, Andre, Zhang, Xuejun, Liu, Jianjun
Published in Nature communications (23.04.2015)
Published in Nature communications (23.04.2015)
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Response to Comment “Sex-specific exposures and sex-combined outcomes in two-sample Mendelian randomization may mislead the causal inference” on “Age at menarche, age at natural menopause, and risk of rheumatoid arthritis—a Mendelian randomization study”
Zhu, Jingjing, Niu, Zheng, Alfredsson, Lars, Klareskog, Lars, Padyukov, Leonid, Jiang, Xia
Published in Arthritis research & therapy (26.10.2022)
Published in Arthritis research & therapy (26.10.2022)
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A Role for Noncoding Variation in Schizophrenia
Roussos, Panos, Mitchell, Amanda C., Voloudakis, Georgios, Fullard, John F., Pothula, Venu M., Tsang, Jonathan, Stahl, Eli A., Georgakopoulos, Anastasios, Ruderfer, Douglas M., Charney, Alexander, Okada, Yukinori, Siminovitch, Katherine A., Worthington, Jane, Padyukov, Leonid, Klareskog, Lars, Gregersen, Peter K., Plenge, Robert M., Raychaudhuri, Soumya, Fromer, Menachem, Purcell, Shaun M., Brennand, Kristen J., Robakis, Nikolaos K., Schadt, Eric E., Akbarian, Schahram, Sklar, Pamela
Published in Cell reports (Cambridge) (20.11.2014)
Published in Cell reports (Cambridge) (20.11.2014)
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Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity
Han, Buhm, Diogo, Dorothée, Eyre, Steve, Kallberg, Henrik, Zhernakova, Alexandra, Bowes, John, Padyukov, Leonid, Okada, Yukinori, González-Gay, Miguel A., Rantapää-Dahlqvist, Solbritt, Martin, Javier, Huizinga, Tom W.J., Plenge, Robert M., Worthington, Jane, Gregersen, Peter K., Klareskog, Lars, de Bakker, Paul I.W., Raychaudhuri, Soumya
Published in American journal of human genetics (03.04.2014)
Published in American journal of human genetics (03.04.2014)
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Journal Article
High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences
Rivera, Natalia V, Ronninger, Marcus, Shchetynsky, Klementy, Franke, Andre, Nöthen, Markus M, Müller-Quernheim, Joachim, Schreiber, Stefan, Adrianto, Indra, Karakaya, Bekir, van Moorsel, Coline H M, Navratilova, Zdenka, Kolek, Vitezslav, Rybicki, Benjamin A, Iannuzzi, Michael C, Petrek, Martin, Grutters, Jan C, Montgomery, Courtney, Fischer, Annegret, Eklund, Anders, Padyukov, Leonid, Grunewald, Johan
Published in American journal of respiratory and critical care medicine (01.05.2016)
Published in American journal of respiratory and critical care medicine (01.05.2016)
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T-cell transcriptomics from peripheral blood highlights differences between polymyositis and dermatomyositis patients
Houtman, Miranda, Ekholm, Louise, Hesselberg, Espen, Chemin, Karine, Malmström, Vivianne, Reed, Ann M, Lundberg, Ingrid E, Padyukov, Leonid
Published in Arthritis research & therapy (29.08.2018)
Published in Arthritis research & therapy (29.08.2018)
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Journal Article
High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci
Kim, Kwangwoo, Bang, So-Young, Lee, Hye-Soon, Cho, Soo-Kyung, Choi, Chan-Bum, Sung, Yoon-Kyoung, Kim, Tae-Hwan, Jun, Jae-Bum, Yoo, Dae Hyun, Kang, Young Mo, Kim, Seong-Kyu, Suh, Chang-Hee, Shim, Seung-Cheol, Lee, Shin-Seok, Lee, Jisoo, Chung, Won Tae, Choe, Jung-Yoon, Shin, Hyoung Doo, Lee, Jong-Young, Han, Bok-Ghee, Nath, Swapan K, Eyre, Steve, Bowes, John, Pappas, Dimitrios A, Kremer, Joel M, Gonzalez-Gay, Miguel A, Rodriguez-Rodriguez, Luis, Ärlestig, Lisbeth, Okada, Yukinori, Diogo, Dorothée, Liao, Katherine P, Karlson, Elizabeth W, Raychaudhuri, Soumya, Rantapää-Dahlqvist, Solbritt, Martin, Javier, Klareskog, Lars, Padyukov, Leonid, Gregersen, Peter K, Worthington, Jane, Greenberg, Jeffrey D, Plenge, Robert M, Bae, Sang-Cheol
Published in Annals of the rheumatic diseases (01.03.2015)
Published in Annals of the rheumatic diseases (01.03.2015)
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