CD122-Selective IL2 Complexes Reduce Immunosuppression, Promote Treg Fragility, and Sensitize Tumor Response to PD-L1 Blockade
Drerup, Justin M, Deng, Yilun, Pandeswara, Sri Lakshmi, Padrón, Álvaro S, Reyes, Ryan M, Zhang, Xinyue, Mendez, Jenny, Liu, Aijie, Clark, Curtis A, Chen, Wanjiao, Conejo-Garcia, José R, Hurez, Vincent, Gupta, Harshita, Curiel, Tyler J
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Published in Cancer research (Chicago, Ill.) (15.11.2020)
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Chronic mTOR inhibition in mice with rapamycin alters T, B, myeloid, and innate lymphoid cells and gut flora and prolongs life of immune‐deficient mice
Hurez, Vincent, Dao, Vinh, Liu, Aijie, Pandeswara, Srilakshmi, Gelfond, Jonathan, Sun, Lishi, Bergman, Molly, Orihuela, Carlos J., Galvan, Veronica, Padrón, Álvaro, Drerup, Justin, Liu, Yang, Hasty, Paul, Sharp, Zelton Dave, Curiel, Tyler J.
Published in Aging cell (01.12.2015)
Published in Aging cell (01.12.2015)
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IFNα Augments Clinical Efficacy of Regulatory T-cell Depletion with Denileukin Diftitox in Ovarian Cancer
Thibodeaux, Suzanne R, Barnett, Brian B, Pandeswara, Srilakshmi, Wall, Shawna R, Hurez, Vincent, Dao, Vinh, Sun, Lishi, Daniel, Benjamin J, Brumlik, Michael J, Drerup, Justin, Padrón, Álvaro, Whiteside, Teresa, Kryczek, Ilona, Zou, Weiping, Curiel, Tyler J
Published in Clinical cancer research (01.07.2021)
Published in Clinical cancer research (01.07.2021)
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Biphasic Rapamycin Effects in Lymphoma and Carcinoma Treatment
Liu, Yang, Pandeswara, Srilakshmi, Dao, Vinh, Padrón, Álvaro, Drerup, Justin M, Lao, Shunhua, Liu, Aijie, Hurez, Vincent, Curiel, Tyler J
Published in Cancer research (Chicago, Ill.) (15.01.2017)
Published in Cancer research (Chicago, Ill.) (15.01.2017)
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Effect of serum estradiol and leptin levels on thyroid function, food intake and body weight gain in female Wistar rats
Pantaleão, Thiago U., Mousovich, Felippe, Rosenthal, Doris, Padrón, Álvaro S., Carvalho, Denise P., Costa, Vânia M. Corrêa da
Published in Steroids (01.10.2010)
Published in Steroids (01.10.2010)
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The effect of acute exercise session on thyroid hormone economy in rats
Fortunato, Rodrigo Soares, Ignácio, Daniele Leão, Padron, Álvaro Souto, Peçanha, Ramon, Marassi, Michelle Porto, Rosenthal, Doris, Werneck-de-Castro, João Pedro Saar, Carvalho, Denise P
Published in Journal of endocrinology (01.08.2008)
Published in Journal of endocrinology (01.08.2008)
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CD122-selective IL-2 complexes reduce immunosuppression, promote Treg fragility, and sensitize tumor response to PD-L1 blockade
Drerup, Justin M., Deng, Yilun, Pandeswara, Sri Lakshmi, Padrón, Álvaro S., Reyes, Ryan M., Zhang, Xinyue, Mendez, Jenny, Liu, Aijie, Clark, Curtis A., Chen, Wanjiao, Conejo-Garcia, José R., Hurez, Vincent, Gupta, Harshita, Curiel, Tyler J.
Published in Cancer research (Chicago, Ill.) (18.09.2020)
Published in Cancer research (Chicago, Ill.) (18.09.2020)
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Rapamycin directly inhibits T cell lymphoma proliferation at high doses and facilitates immune-independent toxin-mediated killing at a low dose in vivo
Liu, Yang, Pandeswara, Srilakshmi, Dao, Vinh A, Padrón, Álvaro, Hurez, Vincent, Curiel, Tyler J
Published in The Journal of immunology (1950) (01.05.2016)
Published in The Journal of immunology (1950) (01.05.2016)
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Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma
Clark, Curtis A, Gupta, Harshita B, Sareddy, Gangadhara, Pandeswara, Srilakshmi, Lao, Shunhua, Yuan, Bin, Drerup, Justin M, Padron, Alvaro, Conejo-Garcia, José, Murthy, Kruthi, Liu, Yang, Turk, Mary Jo, Thedieck, Kathrin, Hurez, Vincent, Li, Rong, Vadlamudi, Ratna, Curiel, Tyler J
Published in Cancer research (Chicago, Ill.) (01.12.2016)
Published in Cancer research (Chicago, Ill.) (01.12.2016)
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Microencapulated rapamycin prevents carcinogen and inflammation driven colon cancer through immune mechanisms
chen, wanjiao, Dao, Vinh A, Cardenas, Kim, Lao, Shunhua, Padrón, Álvaro, Hasty, Edward P., Sharp, Zelton Dave, Hurez, Vincent, Curiel, Tyler J.
Published in The Journal of immunology (1950) (01.05.2016)
Published in The Journal of immunology (1950) (01.05.2016)
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Considerations for successful cancer immunotherapy in aged hosts
Hurez, Vincent, Padrón, Álvaro, Svatek, Robert S., Curiel, Tyler J.
Published in Experimental gerontology (01.07.2018)
Published in Experimental gerontology (01.07.2018)
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Age effects of distinct immune checkpoint blockade treatments in a mouse melanoma model
Padrón, Álvaro, Hurez, Vincent, Gupta, Harshita B., Clark, Curtis A., Pandeswara, Sri Lakshmi, Yuan, Bin, Svatek, Robert S., Turk, Mary Jo, Drerup, Justin M., Li, Rong, Curiel, Tyler J.
Published in Experimental gerontology (01.05.2018)
Published in Experimental gerontology (01.05.2018)
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Tumor Intrinsic PD-L1 Promotes DNA Repair in Distinct Cancers and Suppresses PARP Inhibitor-Induced Synthetic Lethality
Kornepati, Anand V R, Boyd, Jacob T, Murray, Clare E, Saifetiarova, Julia, de la Peña Avalos, Bárbara, Rogers, Cody M, Bai, Haiyan, Padron, Alvaro S, Liao, Yiji, Ontiveros, Carlos, Svatek, Robert S, Hromas, Robert, Li, Rong, Hu, Yanfen, Conejo-Garcia, Jose R, Vadlamudi, Ratna K, Zhao, Weixing, Dray, Eloïse, Sung, Patrick, Curiel, Tyler J
Published in Cancer research (Chicago, Ill.) (06.06.2022)
Published in Cancer research (Chicago, Ill.) (06.06.2022)
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Efeito da suplementação de beta-caroteno na pressão arterial de ratos
Oliveira, Giselle Santos de(Universidade Federal do Estado do Rio de Janeiro Escola de Nutrição), Figueiredo, Álvaro Souto Padrón de(Universidade Federal do Estado do Rio de Janeiro Escola de Nutrição), Santos, Rosane de Souza(Universidade Federal do Estado do Rio de Janeiro), Vianna, Lucia Marques(Universidade Federal do Estado do Rio de Janeiro Laboratório de Investigação em Nutrição e Doenças Crônico-Degenerativas)
Published in Revista de nutrição (2007)
Published in Revista de nutrição (2007)
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MTOR downregulates iodide uptake in thyrocytes
Souza, Elaine Cristina Lima de, Padrón, Álvaro Souto, Braga, William Miranda Oliveira, Andrade, Bruno Moulin de, Vaisman, Mário, Nasciutti, Luiz Eurico, Ferreira, Andrea Claudia Freitas, Carvalho, Denise Pires de
Published in Journal of endocrinology (01.07.2010)
Published in Journal of endocrinology (01.07.2010)
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Bladder cancer cell‐intrinsic PD‐L1 signals promote mTOR and autophagy activation that can be inhibited to improve cytotoxic chemotherapy
Zhang, Deyi, Reyes, Ryan M., Osta, Erica, Kari, Suresh, Gupta, Harshita B., Padron, Alvaro S., Kornepati, Anand V. R., Kancharla, Aravind, Sun, Xiujie, Deng, Yilun, Wu, Bogang, Vadlamudi, Ratna, Li, Rong, Svatek, Robert S., Curiel, Tyler J.
Published in Cancer medicine (Malden, MA) (01.03.2021)
Published in Cancer medicine (Malden, MA) (01.03.2021)
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Tumor cell-intrinsic PD-L1 promotes tumor-initiating cell generation and functions in melanoma and ovarian cancer
Gupta, Harshita B, Clark, Curtis A, Yuan, Bin, Sareddy, Gangadhara, Pandeswara, Srilakshmi, Padron, Alvaro S, Hurez, Vincent, Conejo-Garcia, José, Vadlamudi, Ratna, Li, Rong, Curiel, Tyler J
Published in Signal transduction and targeted therapy (23.12.2016)
Published in Signal transduction and targeted therapy (23.12.2016)
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Tumour-intrinsic PDL1 signals regulate the Chk2 DNA damage response in cancer cells and mediate resistance to Chk1 inhibitors
Murray, Clare E, Kornepati, Anand V R, Ontiveros, Carlos, Liao, Yiji, de la Peña Avalos, Bárbara, Rogers, Cody M, Liu, Zexuan, Deng, Yilun, Bai, Haiyan, Kari, Suresh, Padron, Alvaro S, Boyd, Jacob T, Reyes, Ryan, Clark, Curtis A, Svatek, Robert S, Li, Rong, Hu, Yanfen, Wang, Meiling, Conejo-Garcia, José R, Byers, Lauren A, Ramkumar, Kavya, Sood, Anil K, Lee, Jung-Min, Burd, Christin E, Vadlamudi, Ratna K, Gupta, Harshita B, Zhao, Weixing, Dray, Eloïse, Sung, Patrick, Curiel, Tyler J
Published in Molecular cancer (30.10.2024)
Published in Molecular cancer (30.10.2024)
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CD122-targeted interleukin-2 and αPD-L1 treat bladder cancer and melanoma via distinct mechanisms, including CD122-driven natural killer cell maturation
Reyes, Ryan M, Zhang, Chenghao, Deng, Yilun, Ji, Niannian, Mukherjee, Neelam, Padron, Alvaro S, Clark, Curtis A, Svatek, Robert S, Curiel, Tyler J
Published in Oncoimmunology (01.01.2021)
Published in Oncoimmunology (01.01.2021)
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