Base excision repair defects invoke hypersensitivity to PARP inhibition
Horton, Julie K, Stefanick, Donna F, Prasad, Rajendra, Gassman, Natalie R, Kedar, Padmini S, Wilson, Samuel H
Published in Molecular cancer research (01.08.2014)
Published in Molecular cancer research (01.08.2014)
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Journal Article
DNA polymerases beta and lambda mediate overlapping and independent roles in base excision repair in mouse embryonic fibroblasts
Braithwaite, Elena K, Kedar, Padmini S, Stumpo, Deborah J, Bertocci, Barbara, Freedman, Jonathan H, Samson, Leona D, Wilson, Samuel H
Published in PloS one (18.08.2010)
Published in PloS one (18.08.2010)
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Journal Article
HMGB1 Is a Cofactor in Mammalian Base Excision Repair
Prasad, Rajendra, Liu, Yuan, Deterding, Leesa J., Poltoratsky, Vladimir P., Kedar, Padmini S., Horton, Julie K., Kanno, Shin-Ichiro, Asagoshi, Kenjiro, Hou, Esther W., Khodyreva, Svetlana N., Lavrik, Olga I., Tomer, Kenneth B., Yasui, Akira, Wilson, Samuel H.
Published in Molecular cell (07.09.2007)
Published in Molecular cell (07.09.2007)
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Journal Article
HMGN1 Protein Regulates Poly(ADP-ribose) Polymerase-1 (PARP-1) Self-PARylation in Mouse Fibroblasts
Masaoka, Aya, Gassman, Natalie R., Kedar, Padmini S., Prasad, Rajendra, Hou, Esther W., Horton, Julie K., Bustin, Michael, Wilson, Samuel H.
Published in The Journal of biological chemistry (10.08.2012)
Published in The Journal of biological chemistry (10.08.2012)
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Journal Article
Hyperactivation of PARP triggers nonhomologous end-joining in repair-deficient mouse fibroblasts
Gassman, Natalie R, Stefanick, Donna F, Kedar, Padmini S, Horton, Julie K, Wilson, Samuel H
Published in PloS one (07.11.2012)
Published in PloS one (07.11.2012)
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Journal Article
Interaction between DNA Polymerase β and BRCA1
Masaoka, Aya, Gassman, Natalie R, Horton, Julie K, Kedar, Padmini S, Witt, Kristine L, Hobbs, Cheryl A, Kissling, Grace E, Tano, Keizo, Asagoshi, Kenjiro, Wilson, Samuel H
Published in PloS one (27.06.2013)
Published in PloS one (27.06.2013)
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Journal Article
Poly(ADP-ribose) Polymerase Activity Prevents Signaling Pathways for Cell Cycle Arrest after DNA Methylating Agent Exposure
Horton, Julie K., Stefanick, Donna F., Naron, Jana M., Kedar, Padmini S., Wilson, Samuel H.
Published in The Journal of biological chemistry (22.04.2005)
Published in The Journal of biological chemistry (22.04.2005)
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Journal Article
Interaction between PARP-1 and ATR in mouse fibroblasts is blocked by PARP inhibition
Kedar, Padmini S., Stefanick, Donna F., Horton, Julie K., Wilson, Samuel H.
Published in DNA repair (01.11.2008)
Published in DNA repair (01.11.2008)
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Journal Article
Increased PARP-1 association with DNA in alkylation damaged, PARP-inhibited mouse fibroblasts
Kedar, Padmini S, Stefanick, Donna F, Horton, Julie K, Wilson, Samuel H
Published in Molecular cancer research (01.03.2012)
Published in Molecular cancer research (01.03.2012)
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Journal Article
Coordination of Steps in Single-nucleotide Base Excision Repair Mediated by Apurinic/Apyrimidinic Endonuclease 1 and DNA Polymerase β
Liu, Yuan, Prasad, Rajendra, Beard, William A., Kedar, Padmini S., Hou, Esther W., Shock, David D., Wilson, Samuel H.
Published in The Journal of biological chemistry (04.05.2007)
Published in The Journal of biological chemistry (04.05.2007)
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Journal Article
Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses
Horton, Julie K., Stefanick, Donna F., Gassman, Natalie R., Williams, Jason G., Gabel, Scott A., Cuneo, Matthew J., Prasad, Rajendra, Kedar, Padmini S., DeRose, Eugene F., Hou, Esther W., London, Robert E., Wilson, Samuel H.
Published in DNA repair (01.09.2013)
Published in DNA repair (01.09.2013)
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Journal Article
DNA Polymerase λ Protects Mouse Fibroblasts against Oxidative DNA Damage and Is Recruited to Sites of DNA Damage/Repair
Braithwaite, Elena K., Kedar, Padmini S., Lan, Li, Polosina, Yaroslava Y., Asagoshi, Kenjiro, Poltoratsky, Vladimir P., Horton, Julie K., Miller, Holly, Teebor, George W., Yasui, Akira, Wilson, Samuel H.
Published in The Journal of biological chemistry (09.09.2005)
Published in The Journal of biological chemistry (09.09.2005)
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Journal Article
Base excision repair and design of small molecule inhibitors of human DNA polymerase β
Wilson, Samuel H, Beard, William A, Shock, David D, Batra, Vinod K, Cavanaugh, Nisha A, Prasad, Rajendra, Hou, Esther W, Liu, Yuan, Asagoshi, Kenjiro, Horton, Julie K, Stefanick, Donna F, Kedar, Padmini S, Carrozza, Michael J, Masaoka, Aya, Heacock, Michelle L
Published in Cellular and molecular life sciences : CMLS (01.11.2010)
Published in Cellular and molecular life sciences : CMLS (01.11.2010)
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Journal Article
Direct interaction between mammalian DNA polymerase beta and proliferating cell nuclear antigen
Kedar, Padmini S, Kim, Soon-Jong, Robertson, Anthony, Hou, Esther, Prasad, Rajendra, Horton, Julie K, Wilson, Samuel H
Published in The Journal of biological chemistry (23.08.2002)
Published in The Journal of biological chemistry (23.08.2002)
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Journal Article
The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity
Harrigan, Jeanine A, Opresko, Patricia L, von Kobbe, Cayetano, Kedar, Padmini S, Prasad, Rajendra, Wilson, Samuel H, Bohr, Vilhelm A
Published in The Journal of biological chemistry (20.06.2003)
Published in The Journal of biological chemistry (20.06.2003)
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Journal Article
ATR signaling mediates an S-phase checkpoint after inhibition of poly(ADP-ribose) polymerase activity
Horton, Julie K., Stefanick, Donna F., Kedar, Padmini S., Wilson, Samuel H.
Published in DNA repair (01.06.2007)
Published in DNA repair (01.06.2007)
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Journal Article
Mechanism of HIV reverse transcriptase: enzyme-primer interaction as revealed through studies of a dNTP analog, 3'-azido-dTTP
Kedar, Padmini S, Abbotts, John, Kovacs, Terez, Lesiak, Krystyna, Torrence, Paul, Wilson, Samuel H
Published in Biochemistry (Easton) (17.04.1990)
Published in Biochemistry (Easton) (17.04.1990)
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Journal Article
The ATF/CREB Transcription Factor-Binding Site in the Polymerase β Promoter Mediates the Positive Effect of N-Methyl-N'-Nitro-N- Nitrosoguanidine on Transcription
Kedar, P S, Widen, S G, Englander, E W, Fornace, Jr, A J, Wilson, S H
Published in Proceedings of the National Academy of Sciences - PNAS (01.05.1991)
Published in Proceedings of the National Academy of Sciences - PNAS (01.05.1991)
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Journal Article
DNA Polymerases [beta] and [lambda] Mediate Overlapping and Independent Roles in Base Excision Repair in Mouse Embryonic Fibroblasts
Braithwaite, Elena K, Kedar, Padmini S, Stumpo, Deborah J, Bertocci, Barbara, Freedman, Jonathan H, Samson, Leona D, Wilson, Samuel H
Published in PloS one (18.08.2010)
Published in PloS one (18.08.2010)
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Journal Article