Regulation of Autophagy by Nuclear GAPDH and Its Aggregates in Cancer and Neurodegenerative Disorders
Butera, Giovanna, Mullappilly, Nidula, Masetto, Francesca, Palmieri, Marta, Scupoli, Maria Teresa, Pacchiana, Raffaella, Donadelli, Massimo
Published in International journal of molecular sciences (26.04.2019)
Published in International journal of molecular sciences (26.04.2019)
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Journal Article
To metabolomics and beyond: a technological portfolio to investigate cancer metabolism
Danzi, Federica, Pacchiana, Raffaella, Mafficini, Andrea, Scupoli, Maria T, Scarpa, Aldo, Donadelli, Massimo, Fiore, Alessandra
Published in Signal transduction and targeted therapy (22.03.2023)
Published in Signal transduction and targeted therapy (22.03.2023)
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3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death
Pacchiana, Raffaella, Mullappilly, Nidula, Pinto, Andrea, Bova, Stefania, Forciniti, Stefania, Cullia, Gregorio, Dalla Pozza, Elisa, Bottani, Emanuela, Decimo, Ilaria, Dando, Ilaria, Bruno, Stefano, Conti, Paola, Donadelli, Massimo
Published in Cancers (27.06.2022)
Published in Cancers (27.06.2022)
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Extracellular Matrix Composition Modulates the Responsiveness of Differentiated and Stem Pancreatic Cancer Cells to Lipophilic Derivate of Gemcitabine
Forciniti, Stefania, Dalla Pozza, Elisa, Greco, Maria Raffaella, Amaral Carvalho, Tiago Miguel, Rolando, Barbara, Ambrosini, Giulia, Carmona-Carmona, Cristian Andres, Pacchiana, Raffaella, Di Molfetta, Daria, Donadelli, Massimo, Arpicco, Silvia, Palmieri, Marta, Reshkin, Stephan Joel, Dando, Ilaria, Cardone, Rosa Angela
Published in International journal of molecular sciences (22.12.2020)
Published in International journal of molecular sciences (22.12.2020)
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Journal Article
Redox Sensitive Cysteine Residues as Crucial Regulators of Wild-Type and Mutant p53 Isoforms
Butturini, Elena, Butera, Giovanna, Pacchiana, Raffaella, Carcereri de Prati, Alessandra, Mariotto, Sofia, Donadelli, Massimo
Published in Cells (Basel, Switzerland) (12.11.2021)
Published in Cells (Basel, Switzerland) (12.11.2021)
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Tumor Suppressor Role of Wild-Type P53-Dependent Secretome and Its Proteomic Identification in PDAC
Butera, Giovanna, Manfredi, Marcello, Fiore, Alessandra, Brandi, Jessica, Pacchiana, Raffaella, De Giorgis, Veronica, Barberis, Elettra, Vanella, Virginia, Galasso, Marilisa, Scupoli, Maria Teresa, Marengo, Emilio, Cecconi, Daniela, Donadelli, Massimo
Published in Biomolecules (Basel, Switzerland) (13.02.2022)
Published in Biomolecules (Basel, Switzerland) (13.02.2022)
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Journal Article
Autocrine mechanisms of cancer chemoresistance
Butera, Giovanna, Pacchiana, Raffaella, Donadelli, Massimo
Published in Seminars in cell & developmental biology (01.06.2018)
Published in Seminars in cell & developmental biology (01.06.2018)
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Journal Article
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity
Butera, Giovanna, Pacchiana, Raffaella, Mullappilly, Nidula, Margiotta, Marilena, Bruno, Stefano, Conti, Paola, Riganti, Chiara, Donadelli, Massimo
Published in Biochimica et biophysica acta. Molecular cell research (01.12.2018)
Published in Biochimica et biophysica acta. Molecular cell research (01.12.2018)
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Journal Article
Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: Involvement in cancer invasion and metastasis
Cordani, Marco, Pacchiana, Raffaella, Butera, Giovanna, D'Orazi, Gabriella, Scarpa, Aldo, Donadelli, Massimo
Published in Cancer letters (01.07.2016)
Published in Cancer letters (01.07.2016)
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Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells
Galbiati, Andrea, Bova, Stefania, Pacchiana, Raffaella, Borsari, Chiara, Persico, Marco, Zana, Aureliano, Bruno, Stefano, Donadelli, Massimo, Fattorusso, Caterina, Conti, Paola
Published in European journal of medicinal chemistry (05.06.2023)
Published in European journal of medicinal chemistry (05.06.2023)
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The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition
Brandi, Jessica, Cecconi, Daniela, Cordani, Marco, Torrens-Mas, Margalida, Pacchiana, Raffaella, Dalla Pozza, Elisa, Butera, Giovanna, Manfredi, Marcello, Marengo, Emilio, Oliver, Jordi, Roca, Pilar, Dando, Ilaria, Donadelli, Massimo
Published in Free radical biology & medicine (01.12.2016)
Published in Free radical biology & medicine (01.12.2016)
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Journal Article
Mutant p53 induces SIRT3/MnSOD axis to moderate ROS production in melanoma cells
Torrens-Mas, Margalida, Cordani, Marco, Mullappilly, Nidula, Pacchiana, Raffaella, Riganti, Chiara, Palmieri, Marta, Pons, Daniel G., Roca, Pilar, Oliver, Jordi, Donadelli, Massimo
Published in Archives of biochemistry and biophysics (15.01.2020)
Published in Archives of biochemistry and biophysics (15.01.2020)
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Journal Article
UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism
Dando, Ilaria, Pacchiana, Raffaella, Pozza, Elisa Dalla, Cataldo, Ivana, Bruno, Stefano, Conti, Paola, Cordani, Marco, Grimaldi, Anna, Butera, Giovanna, Caraglia, Michele, Scarpa, Aldo, Palmieri, Marta, Donadelli, Massimo
Published in Free radical biology & medicine (01.12.2017)
Published in Free radical biology & medicine (01.12.2017)
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Journal Article
Trichostatin A alters cytoskeleton and energy metabolism of pancreatic adenocarcinoma cells: An in depth proteomic study
Dalla Pozza, Elisa, Manfredi, Marcello, Brandi, Jessica, Buzzi, Arianna, Conte, Eleonora, Pacchiana, Raffaella, Cecconi, Daniela, Marengo, Emilio, Donadelli, Massimo
Published in Journal of cellular biochemistry (01.03.2018)
Published in Journal of cellular biochemistry (01.03.2018)
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Journal Article
Oncometabolites in cancer aggressiveness and tumour repopulation
Dando, Ilaria, Pozza, Elisa Dalla, Ambrosini, Giulia, Torrens‐Mas, Margalida, Butera, Giovanna, Mullappilly, Nidula, Pacchiana, Raffaella, Palmieri, Marta, Donadelli, Massimo
Published in Biological reviews of the Cambridge Philosophical Society (01.08.2019)
Published in Biological reviews of the Cambridge Philosophical Society (01.08.2019)
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Journal Article
Do astrocytes collaborate with neurons in spreading the "infectious" aβ and Tau drivers of Alzheimer's disease?
Dal Prà, Ilaria, Chiarini, Anna, Gui, Li, Chakravarthy, Balu, Pacchiana, Raffaella, Gardenal, Emanuela, Whitfield, James F, Armato, Ubaldo
Published in The Neuroscientist (Baltimore, Md.) (01.02.2015)
Published in The Neuroscientist (Baltimore, Md.) (01.02.2015)
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Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O2ˉ· production in cancer cells
Cordani, Marco, Butera, Giovanna, Dando, Ilaria, Torrens-Mas, Margalida, Butturini, Elena, Pacchiana, Raffaella, Oppici, Elisa, Cavallini, Chiara, Gasperini, Sara, Tamassia, Nicola, Nadal-Serrano, Mercedes, Coan, Michela, Rossi, Davide, Gaidano, Gianluca, Caraglia, Michele, Mariotto, Sofia, Spizzo, Riccardo, Roca, Pilar, Oliver, Jordi, Scupoli, Maria Teresa, Donadelli, Massimo
Published in British journal of cancer (15.10.2018)
Published in British journal of cancer (15.10.2018)
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