Evaluation of recent Protein A stationary phase innovations for capture of biotherapeutics
Pabst, Timothy M., Thai, Johnny, Hunter, Alan K.
Published in Journal of Chromatography A (15.06.2018)
Published in Journal of Chromatography A (15.06.2018)
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Journal Article
Engineering of novel Staphylococcal Protein A ligands to enable milder elution pH and high dynamic binding capacity
Pabst, Timothy M., Palmgren, Ronnie, Forss, Annika, Vasic, Jelena, Fonseca, Mariko, Thompson, Christopher, Wang, William K., Wang, Xiangyang, Hunter, Alan K.
Published in Journal of Chromatography A (03.10.2014)
Published in Journal of Chromatography A (03.10.2014)
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Journal Article
pH transitions in cation exchange chromatographic columns containing weak acid groups
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Journal Article
Conference Proceeding
Comparison of agarose and dextran-grafted agarose strong ion exchangers for the separation of protein aggregates
Suda, Eric J., Thomas, Kristin E., Pabst, Timothy M., Mensah, Paul, Ramasubramanyan, Natraj, Gustafson, Mark E., Hunter, Alan K.
Published in Journal of Chromatography A (03.07.2009)
Published in Journal of Chromatography A (03.07.2009)
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Journal Article
Comparison of strong anion-exchangers for the purification of a PEGylated protein
Pabst, Timothy M., Buckley, John J., Ramasubramanyan, Natraj, Hunter, Alan K.
Published in Journal of Chromatography A (20.04.2007)
Published in Journal of Chromatography A (20.04.2007)
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Journal Article
Process-scale purification and analytical characterization of highly gamma-carboxylated recombinant human prothrombin
Wendeler, Michaela, Pabst, Timothy M., Wang, Jihong, Strouse, Robert J., Wang, Xiangyang, Hunter, Alan K.
Published in Journal of Chromatography A (17.01.2014)
Published in Journal of Chromatography A (17.01.2014)
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Journal Article
Formation of transient highly-charged mAb clusters strengthens interactions with host cell proteins and results in poor clearance of host cell proteins by protein A chromatography
Luo, Haibin, Du, Qun, Qian, Chen, Mlynarczyk, Michelle, Pabst, Timothy M., Damschroder, Melissa, Hunter, Alan K., Wang, William K.
Published in Journal of Chromatography A (30.08.2022)
Published in Journal of Chromatography A (30.08.2022)
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Journal Article
Separation of antibody monomer-dimer mixtures by frontal analysis
Reck, Jason M., Pabst, Timothy M., Hunter, Alan K., Carta, Giorgio
Published in Journal of Chromatography A (02.06.2017)
Published in Journal of Chromatography A (02.06.2017)
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Journal Article
Cathepsin L Causes Proteolytic Cleavage of Chinese‐Hamster‐Ovary Cell Expressed Proteins During Processing and Storage: Identification, Characterization, and Mitigation
Luo, Haibin, Tie, Liu, Cao, Mingyan, Hunter, Alan K., Pabst, Timothy M., Du, Jiali, Field, Raymond, Li, Yuling, Wang, William K.
Published in Biotechnology progress (01.01.2019)
Published in Biotechnology progress (01.01.2019)
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Journal Article
Safety risk management for low molecular weight process‐related impurities in monoclonal antibody therapeutics: Categorization, risk assessment, testing strategy, and process development with leveraging clearance potential
Luo, Haibin, Li, Yuling, Robbins, David, Wang, Sheau‐Chiann, Xi, Guoling, Cox, Matthew, Nicholson, Simone M., Wei, Chenghong, Pabst, Timothy M., Wang, William K.
Published in Biotechnology progress (01.05.2021)
Published in Biotechnology progress (01.05.2021)
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Journal Article
Process optimization and protein engineering mitigated manufacturing challenges of a monoclonal antibody with liquid-liquid phase separation issue by disrupting inter-molecule electrostatic interactions
Du, Qun, Damschroder, Melissa, Pabst, Timothy M, Hunter, Alan K, Wang, William K, Luo, Haibin
Published in mAbs (19.05.2019)
Published in mAbs (19.05.2019)
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Journal Article
Camelid VHH affinity ligands enable separation of closely related biopharmaceuticals
Pabst, Timothy M., Wendeler, Michaela, Wang, Xiangyang, Bezemer, Sandra, Hermans, Pim, Hunter, Alan K.
Published in Biotechnology journal (01.02.2017)
Published in Biotechnology journal (01.02.2017)
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Journal Article
Development and scale-up of a commercial fed batch refolding process for an anti-CD22 two chain immunotoxin
Linke, Thomas, Aspelund, Matthew T., Thompson, Christopher, Xi, Guoling, Fulton, Andrew, Wendeler, Michaela, Pabst, Timothy M., Wang, Xiangyang, Wang, William K., Ram, Kripa, Hunter, Alan K.
Published in Biotechnology progress (01.11.2014)
Published in Biotechnology progress (01.11.2014)
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Journal Article