Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture
Paşca, Anca M, Sloan, Steven A, Clarke, Laura E, Tian, Yuan, Makinson, Christopher D, Huber, Nina, Kim, Chul Hoon, Park, Jin-Young, O'Rourke, Nancy A, Nguyen, Khoa D, Smith, Stephen J, Huguenard, John R, Geschwind, Daniel H, Barres, Ben A, Paşca, Sergiu P
Published in Nature methods (01.07.2015)
Published in Nature methods (01.07.2015)
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Dissecting the molecular basis of human interneuron migration in forebrain assembloids from Timothy syndrome
Birey, Fikri, Li, Min-Yin, Gordon, Aaron, Thete, Mayuri V., Valencia, Alfredo M., Revah, Omer, Paşca, Anca M., Geschwind, Daniel H., Paşca, Sergiu P.
Published in Cell stem cell (03.02.2022)
Published in Cell stem cell (03.02.2022)
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Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome
Paşca, Sergiu P, Portmann, Thomas, Voineagu, Irina, Yazawa, Masayuki, Shcheglovitov, Aleksandr, Paşca, Anca M, Cord, Branden, Palmer, Theo D, Chikahisa, Sachiko, Nishino, Seiji, Bernstein, Jonathan A, Hallmayer, Joachim, Geschwind, Daniel H, Dolmetsch, Ricardo E
Published in Nature medicine (01.12.2011)
Published in Nature medicine (01.12.2011)
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Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution
Trevino, Alexandro E., Müller, Fabian, Andersen, Jimena, Sundaram, Laksshman, Kathiria, Arwa, Shcherbina, Anna, Farh, Kyle, Chang, Howard Y., Pașca, Anca M., Kundaje, Anshul, Pașca, Sergiu P., Greenleaf, William J.
Published in Cell (16.09.2021)
Published in Cell (16.09.2021)
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Journal Article
Generation and assembly of human brain region–specific three-dimensional cultures
Sloan, Steven A., Andersen, Jimena, Pașca, Anca M., Birey, Fikri, Pașca, Sergiu P.
Published in Nature protocols (01.09.2018)
Published in Nature protocols (01.09.2018)
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Journal Article
Reliability of human cortical organoid generation
Yoon, Se-Jin, Elahi, Lubayna S., Pașca, Anca M., Marton, Rebecca M., Gordon, Aaron, Revah, Omer, Miura, Yuki, Walczak, Elisabeth M., Holdgate, Gwendolyn M., Fan, H. Christina, Huguenard, John R., Geschwind, Daniel H., Pașca, Sergiu P.
Published in Nature methods (01.01.2019)
Published in Nature methods (01.01.2019)
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Human 3D cellular model of hypoxic brain injury of prematurity
Pașca, Anca M., Park, Jin-Young, Shin, Hyun-Woo, Qi, Qihao, Revah, Omer, Krasnoff, Rebecca, O’Hara, Ruth, Willsey, A. Jeremy, Palmer, Theo D., Pașca, Sergiu P.
Published in Nature medicine (01.05.2019)
Published in Nature medicine (01.05.2019)
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Single-cell transcriptomic landscape of the developing human spinal cord
Andersen, Jimena, Thom, Nicholas, Shadrach, Jennifer L., Chen, Xiaoyu, Onesto, Massimo Mario, Amin, Neal D., Yoon, Se-Jin, Li, Li, Greenleaf, William J., Müller, Fabian, Pașca, Anca M., Kaltschmidt, Julia A., Pașca, Sergiu P.
Published in Nature neuroscience (01.05.2023)
Published in Nature neuroscience (01.05.2023)
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Journal Article
The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C
Pluvinage, John V, Sun, Jerry, Claes, Christel, Flynn, Ryan A, Haney, Michael S, Iram, Tal, Meng, Xiangling, Lindemann, Rachel, Riley, Nicholas M, Danhash, Emma, Chadarevian, Jean Paul, Tapp, Emma, Gate, David, Kondapavulur, Sravani, Cobos, Inma, Chetty, Sundari, Pașca, Anca M, Pașca, Sergiu P, Berry-Kravis, Elizabeth, Bertozzi, Carolyn R, Blurton-Jones, Mathew, Wyss-Coray, Tony
Published in Science translational medicine (01.12.2021)
Published in Science translational medicine (01.12.2021)
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Anatomical and functional maturation of the mid-gestation human enteric nervous system
Dershowitz, Lori B., Li, Li, Pasca, Anca M., Kaltschmidt, Julia A.
Published in Nature communications (09.05.2023)
Published in Nature communications (09.05.2023)
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Comparing the efficacy in reducing brain injury of different neuroprotective agents following neonatal hypoxia–ischemia in newborn rats: a multi-drug randomized controlled screening trial
Sabir, Hemmen, Maes, Elke, Zweyer, Margit, Schleehuber, Yvonne, Imam, Farhad B., Silverman, Jared, White, Yasmine, Pang, Raymand, Pasca, Anca M., Robertson, Nicola J., Maltepe, Emin, Bernis, Maria E.
Published in Scientific reports (10.06.2023)
Published in Scientific reports (10.06.2023)
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Blood flow modeling reveals improved collateral artery performance during the regenerative period in mammalian hearts
Anbazhakan, Suhaas, Rios Coronado, Pamela E, Sy-Quia, Ana Natalia L, Seow, Lek Wei, Hands, Aubrey M, Zhao, Mingming, Dong, Melody L, Pfaller, Martin R, Amir, Zhainib A, Raftrey, Brian C, Cook, Christopher K, D'Amato, Gaetano, Fan, Xiaochen, Williams, Ian M, Jha, Sawan K, Bernstein, Daniel, Nieman, Koen, Pașca, Anca M, Marsden, Alison L, Horse, Kristy Red
Published in Nature cardiovascular research (01.08.2022)
Published in Nature cardiovascular research (01.08.2022)
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Human assembloids reveal the consequences of CACNA1G gene variants in the thalamocortical pathway
Kim, Ji-il, Miura, Yuki, Li, Min-Yin, Revah, Omer, Selvaraj, Sridhar, Birey, Fikri, Meng, Xiangling, Thete, Mayuri Vijay, Pavlov, Sergey D., Andersen, Jimena, Pașca, Anca M., Porteus, Matthew H., Huguenard, John R., Pașca, Sergiu P.
Published in Neuron (Cambridge, Mass.) (16.10.2024)
Published in Neuron (Cambridge, Mass.) (16.10.2024)
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Perinatal infection, inflammation, preterm birth, and brain injury: A review with proposals for future investigations
Reiss, Jonathan D., Peterson, Laura S., Nesamoney, Sophia N., Chang, Alan L., Pasca, Anca M., Marić, Ivana, Shaw, Gary M., Gaudilliere, Brice, Wong, Ronald J., Sylvester, Karl G., Bonifacio, Sonia L., Aghaeepour, Nima, Gibbs, Ronald S., Stevenson, David K.
Published in Experimental neurology (01.05.2022)
Published in Experimental neurology (01.05.2022)
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Crosstalk between small-cell lung cancer cells and astrocytes mimics brain development to promote brain metastasis
Qu, Fangfei, Brough, Siqi C., Michno, Wojciech, Madubata, Chioma J., Hartmann, Griffin G., Puno, Alyssa, Drainas, Alexandros P., Bhattacharya, Debadrita, Tomasich, Erwin, Lee, Myung Chang, Yang, Dian, Kim, Jun, Peiris-Pagès, Maria, Simpson, Kathryn L., Dive, Caroline, Preusser, Matthias, Toland, Angus, Kong, Christina, Das, Millie, Winslow, Monte M., Pasca, Anca M., Sage, Julien
Published in Nature cell biology (01.10.2023)
Published in Nature cell biology (01.10.2023)
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Neonatal CSF oxytocin levels are associated with parent report of infant soothability and sociability
Clark, Catherine L, St. John, Nicholas, Pasca, Anca M, Hyde, Shellie A, Hornbeak, Kirsten, Abramova, Marina, Feldman, Heidi, Parker, Karen J, Penn, Anna A
Published in Psychoneuroendocrinology (01.07.2013)
Published in Psychoneuroendocrinology (01.07.2013)
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Increased Tau Expression Correlates with Neuronal Maturation in the Developing Human Cerebral Cortex
Fiock, Kimberly L, Smalley, Martin E, Crary, John F, Pasca, Anca M, Hefti, Marco M
Published in eNeuro (01.05.2020)
Published in eNeuro (01.05.2020)
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Journal Article
Using iPS cell-derived neurons to uncover cellular phenotypes associated with Timothy Syndrome
Paşca, Sergiu P., Portmann, Thomas, Voineagu, Irina, Yazawa, Masayuki, Shcheglovitov, Oleksandr, Paşca, Anca M., Cord, Branden, Palmer, Theo D., Chikahisa, Sachiko, Seiji, Nishino, Bernstein, Jonathan A., Hallmayer, Joachim, Geschwind, Daniel H., Dolmetsch, Ricardo E.
Published in Nature medicine (27.11.2011)
Published in Nature medicine (27.11.2011)
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At the forefront of medical research: our cover authors share their hopes for their fields
Published in Nature medicine
(01.12.2019)
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