A Single CRISPR-Cas9 Deletion Strategy that Targets the Majority of DMD Patients Restores Dystrophin Function in hiPSC-Derived Muscle Cells
Young, Courtney S., Hicks, Michael R., Ermolova, Natalia V., Nakano, Haruko, Jan, Majib, Younesi, Shahab, Karumbayaram, Saravanan, Kumagai-Cresse, Chino, Wang, Derek, Zack, Jerome A., Kohn, Donald B., Nakano, Atsushi, Nelson, Stanley F., Miceli, M. Carrie, Spencer, Melissa J., Pyle, April D.
Published in Cell stem cell (07.04.2016)
Published in Cell stem cell (07.04.2016)
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ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs
Hicks, Michael R., Hiserodt, Julia, Paras, Katrina, Fujiwara, Wakana, Eskin, Ascia, Jan, Majib, Xi, Haibin, Young, Courtney S., Evseenko, Denis, Nelson, Stanley F., Spencer, Melissa J., Handel, Ben Van, Pyle, April D.
Published in Nature cell biology (01.01.2018)
Published in Nature cell biology (01.01.2018)
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Induced Pluripotent Stem Cells and Embryonic Stem Cells Are Distinguished by Gene Expression Signatures
Chin, Mark H., Mason, Mike J., Xie, Wei, Volinia, Stefano, Singer, Mike, Peterson, Cory, Ambartsumyan, Gayane, Aimiuwu, Otaren, Richter, Laura, Zhang, Jin, Khvorostov, Ivan, Ott, Vanessa, Grunstein, Michael, Lavon, Neta, Benvenisty, Nissim, Croce, Carlo M., Clark, Amander T., Baxter, Tim, Pyle, April D., Teitell, Mike A., Pelegrini, Matteo, Plath, Kathrin, Lowry, William E.
Published in Cell stem cell (02.07.2009)
Published in Cell stem cell (02.07.2009)
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Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice
Harn, Hans I-Chen, Wang, Sheng-Pei, Lai, Yung-Chih, Van Handel, Ben, Liang, Ya-Chen, Tsai, Stephanie, Schiessl, Ina Maria, Sarkar, Arijita, Xi, Haibin, Hughes, Michael, Kaemmer, Stefan, Tang, Ming-Jer, Peti-Peterdi, Janos, Pyle, April D., Woolley, Thomas E., Evseenko, Denis, Jiang, Ting-Xin, Chuong, Cheng-Ming
Published in Nature communications (10.05.2021)
Published in Nature communications (10.05.2021)
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Involvement of Lysosomal Exocytosis in the Excretion of Mesoporous Silica Nanoparticles and Enhancement of the Drug Delivery Effect by Exocytosis Inhibition
Yanes, Rolando E., Tarn, Derrick, Hwang, Angela A., Ferris, Daniel P., Sherman, Sean P., Thomas, Courtney R., Lu, Jie, Pyle, April D., Zink, Jeffrey I., Tamanoi, Fuyuhiko
Published in Small (Weinheim an der Bergstrasse, Germany) (11.03.2013)
Published in Small (Weinheim an der Bergstrasse, Germany) (11.03.2013)
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Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes
Ferguson, Gabriel B., Van Handel, Ben, Bay, Maxwell, Fiziev, Petko, Org, Tonis, Lee, Siyoung, Shkhyan, Ruzanna, Banks, Nicholas W., Scheinberg, Mila, Wu, Ling, Saitta, Biagio, Elphingstone, Joseph, Larson, A. Noelle, Riester, Scott M., Pyle, April D., Bernthal, Nicholas M., Mikkola, Hanna KA, Ernst, Jason, van Wijnen, Andre J., Bonaguidi, Michael, Evseenko, Denis
Published in Nature communications (07.09.2018)
Published in Nature communications (07.09.2018)
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Increased lysis of stem cells but not their differentiated cells by natural killer cells; de-differentiation or reprogramming activates NK cells
Tseng, Han-Ching, Arasteh, Aida, Paranjpe, Avina, Teruel, Antonia, Yang, Wendy, Behel, Armin, Alva, Jackelyn A, Walter, Gina, Head, Christian, Ishikawa, Tomo-o, Herschman, Harvey R, Cacalano, Nicholas, Pyle, April D, Park, No-Hee, Jewett, Anahid
Published in PloS one (16.07.2010)
Published in PloS one (16.07.2010)
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Nanoparticles systemically biodistribute to regenerating skeletal muscle in DMD
Hicks, Michael R, Liu, Xiangsheng, Young, Courtney S, Saleh, Kholoud, Ji, Ying, Jiang, Jinhong, Emami, Michael R, Mokhonova, Ekaterina, Spencer, Melissa J, Meng, Huan, Pyle, April D
Published in Journal of nanobiotechnology (29.08.2023)
Published in Journal of nanobiotechnology (29.08.2023)
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Journal Article
Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization
Hazim, Roni A, Karumbayaram, Saravanan, Jiang, Mei, Dimashkie, Anupama, Lopes, Vanda S, Li, Douran, Burgess, Barry L, Vijayaraj, Preethi, Alva-Ornelas, Jackelyn A, Zack, Jerome A, Kohn, Donald B, Gomperts, Brigitte N, Pyle, April D, Lowry, William E, Williams, David S
Published in Stem cell research & therapy (02.10.2017)
Published in Stem cell research & therapy (02.10.2017)
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Journal Article
Creation of a Novel Humanized Dystrophic Mouse Model of Duchenne Muscular Dystrophy and Application of a CRISPR/Cas9 Gene Editing Therapy
Young, Courtney S., Mokhonova, Ekaterina, Quinonez, Marbella, Pyle, April D., Spencer, Melissa J.
Published in Journal of neuromuscular diseases (2017)
Published in Journal of neuromuscular diseases (2017)
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Journal Article
REST/NRSF Knockdown Alters Survival, Lineage Differentiation and Signaling in Human Embryonic Stem Cells
Thakore-Shah, Kaushali, Koleilat, Tasneem, Jan, Majib, John, Alan, Pyle, April D
Published in PloS one (21.12.2015)
Published in PloS one (21.12.2015)
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Journal Article
In Vivo Human Somitogenesis Guides Somite Development from hPSCs
Xi, Haibin, Fujiwara, Wakana, Gonzalez, Karen, Jan, Majib, Liebscher, Simone, Van Handel, Ben, Schenke-Layland, Katja, Pyle, April D.
Published in Cell reports (Cambridge) (07.02.2017)
Published in Cell reports (Cambridge) (07.02.2017)
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Single cell sequencing maps skeletal muscle cellular diversity as disease severity increases in dystrophic mouse models
Saleh, Kholoud K., Xi, Haibin, Switzler, Corey, Skuratovsky, Emily, Romero, Matthew A., Chien, Peggie, Gibbs, Devin, Gane, Lily, Hicks, Michael R., Spencer, Melissa J., Pyle, April D.
Published in iScience (18.11.2022)
Published in iScience (18.11.2022)
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Journal Article
Innate and adaptive AAV-mediated immune responses in a mouse model of Duchenne muscular dystrophy
Emami, Michael R., Espinoza, Alejandro, Young, Courtney S., Ma, Feiyang, Farahat, Philip K., Felgner, Philip L., Chamberlain, Jeffrey S., Xu, Xiangmin, Pyle, April D., Pellegrini, Matteo, Villalta, S. Armando, Spencer, Melissa J.
Published in Molecular therapy. Methods & clinical development (14.09.2023)
Published in Molecular therapy. Methods & clinical development (14.09.2023)
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Myoscaffolds reveal laminin scarring is detrimental for stem cell function while sarcospan induces compensatory fibrosis
Stearns-Reider, Kristen M., Hicks, Michael R., Hammond, Katherine G., Reynolds, Joseph C., Maity, Alok, Kurmangaliyev, Yerbol Z., Chin, Jesse, Stieg, Adam Z., Geisse, Nicholas A., Hohlbauch, Sophia, Kaemmer, Stefan, Schmitt, Lauren R., Pham, Thanh T., Yamauchi, Ken, Novitch, Bennett G., Wollman, Roy, Hansen, Kirk C., Pyle, April D., Crosbie, Rachelle H.
Published in npj Regenerative medicine (15.03.2023)
Published in npj Regenerative medicine (15.03.2023)
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