Synthesis of imidazopyridines and purines as potent inhibitors of leukotriene A4 hydrolase
PENNING, Thomas D, CHANDRAKUMAR, Nizal S, HARDING, Elizabeth I, HIGHKIN, Maureen K, KACHUR, James F, KIM, Suzanne H, VILLANI-PRICE, Doreen, PYLA, E. Yvonne, GHOREISHI-HAACK, Nayereh S, SMITH, Walter G, DESAI, Bipin N, DJURIC, Stevan W, GASIECKI, Alan F, MALECHA, James W, MIYASHIRO, Julie M, RUSSELL, Mark A, ASKONAS, Leslie J, GIERSE, James K
Published in Bioorganic & medicinal chemistry letters (24.03.2003)
Published in Bioorganic & medicinal chemistry letters (24.03.2003)
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Structure−Activity Relationship Studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a Potent Inhibitor of Leukotriene A4 (LTA4) Hydrolase
Penning, Thomas D, Chandrakumar, Nizal S, Chen, Barbara B, Chen, Helen Y, Desai, Bipin N, Djuric, Stevan W, Docter, Stephen H, Gasiecki, Alan F, Haack, Richard A, Miyashiro, Julie M, Russell, Mark A, Yu, Stella S, Corley, David G, Durley, Richard C, Kilpatrick, Brian F, Parnas, Barry L, Askonas, Leslie J, Gierse, James K, Harding, Elizabeth I, Highkin, Maureen K, Kachur, James F, Kim, Suzanne H, Krivi, Gwen G, Villani-Price, Doreen, Pyla, E. Yvonne, Smith, Walter G, Ghoreishi-Haack, Nayereh S
Published in Journal of medicinal chemistry (24.02.2000)
Published in Journal of medicinal chemistry (24.02.2000)
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Synthesis of potent leukotriene A(4) hydrolase inhibitors. identification of 3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid
Penning, TD, Russell, MA, Chen, BB, Chen, HY, Liang, CD, Mahoney, MW, Malecha, JW, Miyashiro, JM, Yu, SS, Askonas, LJ, Gierse, JK, Harding, EI, Highkin, MK, Kachur, JF, Kim, SH, Villani-Price, D, Pyla, EY, Ghoreishi-Haack, NS, Smith, WG
Published in Journal of medicinal chemistry (01.08.2002)
Published in Journal of medicinal chemistry (01.08.2002)
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Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A4 hydrolase
PENNING, Thomas D, CHANDRAKUMAR, Nizal S, HARDING, Elizabeth I, HIGHKIN, Maureen K, KACHUR, James F, KIM, Suzanne H, VILLANI-PRICE, Doreen, PYLA, E. Yvonne, GHOREISHI-HAACK, Nayereh S, SMITH, Walter G, DESAI, Bipin N, DJURIC, Stevan W, GASIECKI, Alan F, LIANG, Chi-Dean, MIYASHIRO, Julie M, RUSSELL, Mark A, ASKONAS, Leslie J, GIERSE, James K
Published in Bioorganic & medicinal chemistry letters (01.12.2002)
Published in Bioorganic & medicinal chemistry letters (01.12.2002)
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Journal Article
Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A(4) hydrolase
Penning, Thomas D, Chandrakumar, Nizal S, Desai, Bipin N, Djuric, Stevan W, Gasiecki, Alan F, Liang, Chi-Dean, Miyashiro, Julie M, Russell, Mark A, Askonas, Leslie J, Gierse, James K, Harding, Elizabeth I, Highkin, Maureen K, Kachur, James F, Kim, Suzanne H, Villani-Price, Doreen, Pyla, E Yvonne, Ghoreishi-Haack, Nayereh S, Smith, Walter G
Published in Bioorganic & medicinal chemistry letters (02.12.2002)
Published in Bioorganic & medicinal chemistry letters (02.12.2002)
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Synthesis of Potent Leukotriene A 4 Hydrolase Inhibitors. Identification of 3-[Methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic Acid
Penning, Thomas D., Russell, Mark A., Chen, Barbara B., Chen, Helen Y., Liang, Chi-Dean, Mahoney, Matthew W., Malecha, James W., Miyashiro, Julie M., Yu, Stella S., Askonas, Leslie J., Gierse, James K., Harding, Elizabeth I., Highkin, Maureen K., Kachur, James F., Kim, Suzanne H., Villani-Price, Doreen, Pyla, E. Yvonne, Ghoreishi-Haack, Nayereh S., Smith, Walter G.
Published in Journal of medicinal chemistry (01.08.2002)
Published in Journal of medicinal chemistry (01.08.2002)
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Kelatorphan and related analogs: potent and selective inhibitors of leukotriene A4 hydrolase
Penning, Thomas D., Askonas, Leslie J., Djuric, Stevan W., Haack, Richard A., Yu, Stella S., Michener, Marshall L., Krivi, Gwen G., Pyla, E.Yvonne
Published in Bioorganic & medicinal chemistry letters (02.11.1995)
Published in Bioorganic & medicinal chemistry letters (02.11.1995)
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Synthesis of Potent Leukotriene A4 Hydrolase Inhibitors. Identification of 3-[Methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic Acid
Penning, Thomas D, Russell, Mark A, Chen, Barbara B, Chen, Helen Y, Liang, Chi-Dean, Mahoney, Matthew W, Malecha, James W, Miyashiro, Julie M, Yu, Stella S, Askonas, Leslie J, Gierse, James K, Harding, Elizabeth I, Highkin, Maureen K, Kachur, James F, Kim, Suzanne H, Villani-Price, Doreen, Pyla, E. Yvonne, Ghoreishi-Haack, Nayereh S, Smith, Walter G
Published in Journal of medicinal chemistry (01.08.2002)
Published in Journal of medicinal chemistry (01.08.2002)
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Journal Article
Structure−Activity Relationship Studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a Potent Inhibitor of Leukotriene A 4 (LTA 4 ) Hydrolase
Penning, Thomas D., Chandrakumar, Nizal S., Chen, Barbara B., Chen, Helen Y., Desai, Bipin N., Djuric, Stevan W., Docter, Stephen H., Gasiecki, Alan F., Haack, Richard A., Miyashiro, Julie M., Russell, Mark A., Yu, Stella S., Corley, David G., Durley, Richard C., Kilpatrick, Brian F., Parnas, Barry L., Askonas, Leslie J., Gierse, James K., Harding, Elizabeth I., Highkin, Maureen K., Kachur, James F., Kim, Suzanne H., Krivi, Gwen G., Villani-Price, Doreen, Pyla, E. Yvonne, Smith, Walter G., Ghoreishi-Haack, Nayereh S.
Published in Journal of medicinal chemistry (01.02.2000)
Published in Journal of medicinal chemistry (01.02.2000)
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Comparison of recombinant tissue factor pathway inhibitors expressed in human SK hepatoma, mouse C127, baby hamster kidney, and Chinese hamster ovary cells
Wun, T C, Kretzmer, K K, Palmier, M O, Day, K C, Huang, M D, Welsch, D J, Lewis, C, Wolfe, R A, Zobel, J F, Lange, G W
Published in Thrombosis and haemostasis (06.07.1992)
Published in Thrombosis and haemostasis (06.07.1992)
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