SDF-1 inhibition targets the bone marrow niche for cancer therapy
Roccaro, Aldo M, Sacco, Antonio, Purschke, Werner G, Moschetta, Michele, Buchner, Klaus, Maasch, Christian, Zboralski, Dirk, Zöllner, Stefan, Vonhoff, Stefan, Mishima, Yuji, Maiso, Patricia, Reagan, Michaela R, Lonardi, Silvia, Ungari, Marco, Facchetti, Fabio, Eulberg, Dirk, Kruschinski, Anna, Vater, Axel, Rossi, Giuseppe, Klussmann, Sven, Ghobrial, Irene M
Published in Cell reports (Cambridge) (09.10.2014)
Published in Cell reports (Cambridge) (09.10.2014)
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Journal Article
The effects of the anti-hepcidin Spiegelmer NOX-H94 on inflammation-induced anemia in cynomolgus monkeys
Schwoebel, Frank, van Eijk, Lucas T., Zboralski, Dirk, Sell, Simone, Buchner, Klaus, Maasch, Christian, Purschke, Werner G., Humphrey, Martin, Zöllner, Stefan, Eulberg, Dirk, Morich, Frank, Pickkers, Peter, Klussmann, Sven
Published in Blood (21.03.2013)
Published in Blood (21.03.2013)
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Journal Article
A Novel C5a-neutralizing Mirror-image (l-)Aptamer Prevents Organ Failure and Improves Survival in Experimental Sepsis
Hoehlig, Kai, Maasch, Christian, Shushakova, Nelli, Buchner, Klaus, Huber-Lang, Markus, Purschke, Werner G, Vater, Axel, Klussmann, Sven
Published in Molecular therapy (01.12.2013)
Published in Molecular therapy (01.12.2013)
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Journal Article
Identification and characterization of a mirror-image oligonucleotide that binds and neutralizes sphingosine 1-phosphate, a central mediator of angiogenesis
Purschke, Werner G, Hoehlig, Kai, Buchner, Klaus, Zboralski, Dirk, Schwoebel, Frank, Vater, Axel, Klussmann, Sven
Published in Biochemical journal (15.08.2014)
Published in Biochemical journal (15.08.2014)
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Journal Article
Polyetheylenimine-Polyplexes of Spiegelmer NOX-A50 Directed against Intracellular High Mobility Group Protein A1 (HMGA1) Reduce Tumor Growth in Vivo
Maasch, Christian, Vater, Axel, Buchner, Klaus, Purschke, Werner G., Eulberg, Dirk, Vonhoff, Stefan, Klussmann, Sven
Published in The Journal of biological chemistry (17.12.2010)
Published in The Journal of biological chemistry (17.12.2010)
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Journal Article
A Mixed Mirror-image DNA/RNA Aptamer Inhibits Glucagon and Acutely Improves Glucose Tolerance in Models of Type 1 and Type 2 Diabetes
Vater, Axel, Sell, Simone, Kaczmarek, Przemyslaw, Maasch, Christian, Buchner, Klaus, Pruszynska-Oszmalek, Ewa, Kolodziejski, Pawel, Purschke, Werner G., Nowak, Krzysztof W., Strowski, Mathias Z., Klussmann, Sven
Published in The Journal of biological chemistry (19.07.2013)
Published in The Journal of biological chemistry (19.07.2013)
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Journal Article
An L-RNA-Based Aquaretic Agent That Inhibits Vasopressin in Vivo
Purschke, Werner G., Eulberg, Dirk, Buchner, Klaus, Vonhoff, Stefan, Klussmann, Sven
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.2006)
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Journal Article
Identification of a novel C5a-inhibiting human and mouse-specific Spiegelmer® for treatment of septic shock and its proof of concept in the CLP mouse model
Vater, Axel, Hoehlig, Kai, Maasch, Christian, Buchner, Klaus, Purschke, Werner G, Klussmann, Sven
Published in Immunobiology (1979) (01.11.2012)
Published in Immunobiology (1979) (01.11.2012)
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Journal Article
A DNA Spiegelmer to staphylococcal enterotoxin B
Purschke, Werner G., Radtke, Falko, Kleinjung, Frank, Klussmann, Sven
Published in Nucleic acids research (15.06.2003)
Published in Nucleic acids research (15.06.2003)
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Journal Article
In Vitro Selection against Small Targets
Eulberg, Dirk, Maasch, Christian, Purschke, Werner G, Klussmann, Sven
Published in Handbook of RNA Biochemistry (09.04.2014)
Published in Handbook of RNA Biochemistry (09.04.2014)
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Book Chapter
Evidence for a novel cytoplasmic tRNA-protein complex containing the KH-multidomain protein vigilin
Kruse, C, Grünweller, A, Notbohm, H, Kügler, S, Purschke, W G, Müller, P K
Published in Biochemical journal (15.11.1996)
Published in Biochemical journal (15.11.1996)
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Journal Article
Respiratory chains of archaea and extremophiles
Schäfer, Günter, Purschke, Werner G., Gleissner, Michael, Schmidt, Christian L.
Published in Biochimica et biophysica acta (18.07.1996)
Published in Biochimica et biophysica acta (18.07.1996)
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Journal Article
An l-RNA-based aquaretic agent that inhibits vasopressin invivo
Werner G. Purschke, Dirk Eulberg, Klaus Buchner, Stefan Vonhoff, Sven Klussmann
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.2006)
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Journal Article
Chicken vigilin gene: a distinctive pattern of hypersensitive sites is characteristic for its transcriptional activity
Grünweller, A, Purschke, W G, Kügler, S, Kruse, C, Müller, P K
Published in Biochemical journal (01.09.1997)
Published in Biochemical journal (01.09.1997)
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Journal Article