Structural basis for CARM1 inhibition by indole and pyrazole inhibitors
Sack, John S, Thieffine, Sandrine, Bandiera, Tiziano, Fasolini, Marina, Duke, Gerald J, Jayaraman, Lata, Kish, Kevin F, Klei, Herbert E, Purandare, Ashok V, Rosettani, Pamela, Troiani, Sonia, Xie, Dianlin, Bertrand, Jay A
Published in Biochemical journal (01.06.2011)
Published in Biochemical journal (01.06.2011)
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Journal Article
Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1)
Purandare, Ashok V., Chen, Zhong, Huynh, Tram, Pang, Suhong, Geng, Jieping, Vaccaro, Wayne, Poss, Michael A., Oconnell, Jonathan, Nowak, Kimberly, Jayaraman, Lata
Published in Bioorganic & medicinal chemistry (01.08.2008)
Published in Bioorganic & medicinal chemistry (01.08.2008)
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Journal Article
Optimization of pyrazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)
Huynh, Tram, Chen, Zhong, Pang, Suhong, Geng, Jieping, Bandiera, Tiziano, Bindi, Simona, Vianello, Paola, Roletto, Fulvia, Thieffine, Sandrine, Galvani, Arturo, Vaccaro, Wayne, Poss, Michael A., Trainor, George L., Lorenzi, Matthew V., Gottardis, Marco, Jayaraman, Lata, Purandare, Ashok V.
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
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Journal Article
Inhibition of Casein Kinase 2 Disrupts Differentiation of Myeloid Cells in Cancer and Enhances the Efficacy of Immunotherapy in Mice
Hashimoto, Ayumi, Gao, Chan, Mastio, Jerome, Kossenkov, Andrew, Abrams, Scott I, Purandare, Ashok V, Desilva, Heshani, Wee, Susan, Hunt, John, Jure-Kunkel, Maria, Gabrilovich, Dmitry I
Published in Cancer research (Chicago, Ill.) (01.10.2018)
Published in Cancer research (Chicago, Ill.) (01.10.2018)
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Journal Article
Core exploration in optimization of chemokine receptor CCR4 antagonists
Purandare, Ashok V., Wan, Honghe, Somerville, John E., Burke, Christine, Vaccaro, Wayne, Yang, XiaoXia, McIntyre, Kim W., Poss, Michael A.
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
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Journal Article
Long-Acting Tumor-Activated Prodrug of a TGFβR Inhibitor
Zhang, Yong, Parrish, Karen E, Tortolani, David R, Poss, Michael A, Huang, Audris, Wan, Honghe, Purandare, Ashok V, Donnell, Andrew F, Kempson, James, Hou, Xiaoping, Pawluczyk, Joseph, Yip, Shiuhang, Luk, Emily, Raghavan, Nimmi, Swanson, Jesse, Smalley, James, Murtaza, Anwar, Yang, Zheng, Augustine-Rauch, Karen, Lombardo, Louis J, Borzilleri, Robert
Published in Journal of medicinal chemistry (11.11.2021)
Published in Journal of medicinal chemistry (11.11.2021)
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Journal Article
9H-Carbazole-1-carboxamides as potent and selective JAK2 inhibitors
Zimmermann, Kurt, Sang, Xiaopeng, Mastalerz, Harold A., Johnson, Walter L., Zhang, Guifen, Liu, Qingjie, Batt, Douglas, Lombardo, Louis J., Vyas, Dinesh, Trainor, George L., Tokarski, John S., Lorenzi, Matthew V., You, Dan, Gottardis, Marco M., Lippy, Jonathan, Khan, Javed, Sack, John S., Purandare, Ashok V.
Published in Bioorganic & medicinal chemistry letters (15.07.2015)
Published in Bioorganic & medicinal chemistry letters (15.07.2015)
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Journal Article
Improved conditions for converting sterically hindered amides to 1,5-disubstituted tetrazoles
Schroeder, Gretchen M., Marshall, Sydney, Wan, Honghe, Purandare, Ashok V.
Published in Tetrahedron letters (10.03.2010)
Published in Tetrahedron letters (10.03.2010)
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Journal Article
Benzo[ d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)—Hit to Lead studies
Wan, Honghe, Huynh, Tram, Pang, Suhong, Geng, Jieping, Vaccaro, Wayne, Poss, Michael A., Trainor, George L., Lorenzi, Matthew V., Gottardis, Marco, Jayaraman, Lata, Purandare, Ashok V.
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
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Journal Article
Discovery of a Highly Selective JAK2 Inhibitor, BMS-911543, for the Treatment of Myeloproliferative Neoplasms
Wan, Honghe, Schroeder, Gretchen M, Hart, Amy C, Inghrim, Jennifer, Grebinski, James, Tokarski, John S, Lorenzi, Matthew V, You, Dan, Mcdevitt, Theresa, Penhallow, Becky, Vuppugalla, Ragini, Zhang, Yueping, Gu, Xiaomei, Iyer, Ramaswamy, Lombardo, Louis J, Trainor, George L, Ruepp, Stefan, Lippy, Jonathan, Blat, Yuval, Sack, John S, Khan, Javed A, Stefanski, Kevin, Sleczka, Bogdan, Mathur, Arvind, Sun, Jung-Hui, Wong, Michael K, Wu, Dauh-Rurng, Li, Peng, Gupta, Anuradha, Arunachalam, P. N, Pragalathan, Bala, Narayanan, Sankara, K.C, Nanjundaswamy, Kuppusamy, Prakasam, Purandare, Ashok V
Published in ACS medicinal chemistry letters (13.08.2015)
Published in ACS medicinal chemistry letters (13.08.2015)
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Journal Article
Structure-Based Design of Selective Janus Kinase 2 Imidazo[4,5‑d]pyrrolo[2,3‑b]pyridine Inhibitors
Hart, Amy C, Schroeder, Gretchen M, Wan, Honghe, Grebinski, James, Inghrim, Jennifer, Kempson, James, Guo, Junqing, Pitts, William J, Tokarski, John S, Sack, John S, Khan, Javed A, Lippy, Jonathan, Lorenzi, Matthew V, You, Dan, McDevitt, Theresa, Vuppugalla, Ragini, Zhang, Yueping, Lombardo, Louis J, Trainor, George L, Purandare, Ashok V
Published in ACS medicinal chemistry letters (13.08.2015)
Published in ACS medicinal chemistry letters (13.08.2015)
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Journal Article
Antagonists of CCR4 as immunomodulatory agents
Purandare, Ashok V, Somerville, John E
Published in Current topics in medicinal chemistry (01.07.2006)
Published in Current topics in medicinal chemistry (01.07.2006)
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Journal Article
Identification of chemokine receptor CCR4 antagonist
Purandare, Ashok V., Gao, Aiming, Wan, Honghe, Somerville, John, Burke, Christine, Seachord, Carrie, Vaccaro, Wayne, Wityak, John, Poss, Michael A.
Published in Bioorganic & medicinal chemistry letters (16.05.2005)
Published in Bioorganic & medicinal chemistry letters (16.05.2005)
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Journal Article
Pyrrolo[1,2- f]triazines as JAK2 inhibitors: Achieving potency and selectivity for JAK2 over JAK3
Harikrishnan, Lalgudi S., Kamau, Muthoni G., Wan, Honghe, Inghrim, Jennifer A., Zimmermann, Kurt, Sang, Xiaopeng, Mastalerz, Harold A., Johnson, Walter L., Zhang, Guifen, Lombardo, Louis J., Poss, Michael A., Trainor, George L., Tokarski, John S., Lorenzi, Matthew V., You, Dan, Gottardis, Marco M., Baldwin, Kathy F., Lippy, Jonathan, Nirschl, David S., Qiu, Ruhui, Miller, Arthur V., Khan, Javed, Sack, John S., Purandare, Ashok V.
Published in Bioorganic & medicinal chemistry letters (01.03.2011)
Published in Bioorganic & medicinal chemistry letters (01.03.2011)
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Journal Article
암의 치료를 위한 치환된 옥소이소인돌린 화합물
DEGNAN ANDREW P, PARK PETER KINAM, HUANG AUDRIS, KUMI GODWIN KWAME, PURANDARE ASHOK V, BILDER DONNA M, CHERNEY EMILY, TEBBEN ANDREW J
Year of Publication 30.11.2022
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Year of Publication 30.11.2022
Patent
Diaminopyrimidine and diaminopyridine 5-HT7 ligands
DENHART, Derek J, PURANDARE, Ashok V, MATTSON, Ronald J, CATT, John D, KING, H. Dalton, AIMING GAO, DESKUS, Jeffrey A, POSS, Michael A, STARK, Arlene D, TORRENTE, John R, JOHNSON, Graham
Published in Bioorganic & medicinal chemistry letters (16.08.2004)
Published in Bioorganic & medicinal chemistry letters (16.08.2004)
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