Emerging Variants of Castration-Resistant Prostate Cancer
Vlachostergios, Panagiotis J., Puca, Loredana, Beltran, Himisha
Published in Current Oncology Reports (01.05.2017)
Published in Current Oncology Reports (01.05.2017)
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Book Review
Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity
Cyrta, Joanna, Augspach, Anke, De Filippo, Maria Rosaria, Prandi, Davide, Thienger, Phillip, Benelli, Matteo, Cooley, Victoria, Bareja, Rohan, Wilkes, David, Chae, Sung-Suk, Cavaliere, Paola, Dephoure, Noah, Uldry, Anne-Christine, Lagache, Sophie Braga, Roma, Luca, Cohen, Sandra, Jaquet, Muriel, Brandt, Laura P., Alshalalfa, Mohammed, Puca, Loredana, Sboner, Andrea, Feng, Felix, Wang, Shangqian, Beltran, Himisha, Lotan, Tamara, Spahn, Martin, Kruithof-de Julio, Marianna, Chen, Yu, Ballman, Karla V., Demichelis, Francesca, Piscuoglio, Salvatore, Rubin, Mark A.
Published in Nature communications (03.11.2020)
Published in Nature communications (03.11.2020)
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Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer
Beltran, Himisha, Prandi, Davide, Mosquera, Juan Miguel, Benelli, Matteo, Puca, Loredana, Cyrta, Joanna, Marotz, Clarisse, Giannopoulou, Eugenia, Chakravarthi, Balabhadrapatruni V S K, Varambally, Sooryanarayana, Tomlins, Scott A, Nanus, David M, Tagawa, Scott T, Van Allen, Eliezer M, Elemento, Olivier, Sboner, Andrea, Garraway, Levi A, Rubin, Mark A, Demichelis, Francesca
Published in Nature medicine (01.03.2016)
Published in Nature medicine (01.03.2016)
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N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer
Dardenne, Etienne, Beltran, Himisha, Benelli, Matteo, Gayvert, Kaitlyn, Berger, Adeline, Puca, Loredana, Cyrta, Joanna, Sboner, Andrea, Noorzad, Zohal, MacDonald, Theresa, Cheung, Cynthia, Yuen, Ka Shing, Gao, Dong, Chen, Yu, Eilers, Martin, Mosquera, Juan-Miguel, Robinson, Brian D., Elemento, Olivier, Rubin, Mark A., Demichelis, Francesca, Rickman, David S.
Published in Cancer cell (10.10.2016)
Published in Cancer cell (10.10.2016)
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Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine
Pauli, Chantal, Hopkins, Benjamin D, Prandi, Davide, Shaw, Reid, Fedrizzi, Tarcisio, Sboner, Andrea, Sailer, Verena, Augello, Michael, Puca, Loredana, Rosati, Rachele, McNary, Terra J, Churakova, Yelena, Cheung, Cynthia, Triscott, Joanna, Pisapia, David, Rao, Rema, Mosquera, Juan Miguel, Robinson, Brian, Faltas, Bishoy M, Emerling, Brooke E, Gadi, Vijayakrishna K, Bernard, Brady, Elemento, Olivier, Beltran, Himisha, Demichelis, Francesca, Kemp, Christopher J, Grandori, Carla, Cantley, Lewis C, Rubin, Mark A
Published in Cancer discovery (01.05.2017)
Published in Cancer discovery (01.05.2017)
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Patient derived organoids to model rare prostate cancer phenotypes
Puca, Loredana, Bareja, Rohan, Prandi, Davide, Shaw, Reid, Benelli, Matteo, Karthaus, Wouter R., Hess, Judy, Sigouros, Michael, Donoghue, Adam, Kossai, Myriam, Gao, Dong, Cyrta, Joanna, Sailer, Verena, Vosoughi, Aram, Pauli, Chantal, Churakova, Yelena, Cheung, Cynthia, Deonarine, Lesa Dayal, McNary, Terra J., Rosati, Rachele, Tagawa, Scott T., Nanus, David M., Mosquera, Juan Miguel, Sawyers, Charles L., Chen, Yu, Inghirami, Giorgio, Rao, Rema A., Grandori, Carla, Elemento, Olivier, Sboner, Andrea, Demichelis, Francesca, Rubin, Mark A., Beltran, Himisha
Published in Nature communications (19.06.2018)
Published in Nature communications (19.06.2018)
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Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets
Tang, Fanying, Xu, Duo, Wang, Shangqian, Wong, Chen Khuan, Martinez-Fundichely, Alexander, Lee, Cindy J, Cohen, Sandra, Park, Jane, Hill, Corinne E, Eng, Kenneth, Bareja, Rohan, Han, Teng, Liu, Eric Minwei, Palladino, Ann, Di, Wei, Gao, Dong, Abida, Wassim, Beg, Shaham, Puca, Loredana, Meneses, Maximiliano, de Stanchina, Elisa, Berger, Michael F, Gopalan, Anuradha, Dow, Lukas E, Mosquera, Juan Miguel, Beltran, Himisha, Sternberg, Cora N, Chi, Ping, Scher, Howard I, Sboner, Andrea, Chen, Yu, Khurana, Ekta
Published in Science (American Association for the Advancement of Science) (27.05.2022)
Published in Science (American Association for the Advancement of Science) (27.05.2022)
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ONECUT2 is a driver of neuroendocrine prostate cancer
Guo, Haiyang, Ci, Xinpei, Ahmed, Musaddeque, Hua, Junjie Tony, Soares, Fraser, Lin, Dong, Puca, Loredana, Vosoughi, Aram, Xue, Hui, Li, Estelle, Su, Peiran, Chen, Sujun, Nguyen, Tran, Liang, Yi, Zhang, Yuzhe, Xu, Xin, Xu, Jing, Sheahan, Anjali V., Ba-Alawi, Wail, Zhang, Si, Mahamud, Osman, Vellanki, Ravi N., Gleave, Martin, Bristow, Robert G., Haibe-Kains, Benjamin, Poirier, John T., Rudin, Charles M., Tsao, Ming-Sound, Wouters, Bradly G., Fazli, Ladan, Feng, Felix Y., Ellis, Leigh, van der Kwast, Theo, Berlin, Alejandro, Koritzinsky, Marianne, Boutros, Paul C., Zoubeidi, Amina, Beltran, Himisha, Wang, Yuzhuo, He, Housheng Hansen
Published in Nature communications (17.01.2019)
Published in Nature communications (17.01.2019)
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Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer
Che, Meixia, Chaturvedi, Aashi, Munro, Sarah A., Pitzen, Samuel P., Ling, Alex, Zhang, Weijie, Mentzer, Josh, Ku, Sheng-Yu, Puca, Loredana, Zhu, Yanyun, Bergman, Andries M., Severson, Tesa M., Forster, Colleen, Liu, Yuzhen, Hildebrand, Jacob, Daniel, Mark, Wang, Ting-You, Selth, Luke A., Hickey, Theresa, Zoubeidi, Amina, Gleave, Martin, Bareja, Rohan, Sboner, Andrea, Tilley, Wayne, Carroll, Jason S., Tan, Winston, Kohli, Manish, Yang, Rendong, Hsieh, Andrew C., Murugan, Paari, Zwart, Wilbert, Beltran, Himisha, Huang, R. Stephanie, Dehm, Scott M.
Published in Nature communications (04.11.2021)
Published in Nature communications (04.11.2021)
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Journal Article
SLFN11 Expression in Advanced Prostate Cancer and Response to Platinum-based Chemotherapy
Conteduca, Vincenza, Ku, Sheng-Yu, Puca, Loredana, Slade, Megan, Fernandez, Luisa, Hess, Judy, Bareja, Rohan, Vlachostergios, Panagiotis J, Sigouros, Michael, Mosquera, Juan Miguel, Sboner, Andrea, Nanus, David M, Elemento, Olivier, Dittamore, Ryan, Tagawa, Scott T, Beltran, Himisha
Published in Molecular cancer therapeutics (01.05.2020)
Published in Molecular cancer therapeutics (01.05.2020)
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Lineage-specific canonical and non-canonical activity of EZH2 in advanced prostate cancer subtypes
Venkadakrishnan, Varadha Balaji, Presser, Adam G., Singh, Richa, Booker, Matthew A., Traphagen, Nicole A., Weng, Kenny, Voss, Nathaniel C. E., Mahadevan, Navin R., Mizuno, Kei, Puca, Loredana, Idahor, Osasenaga, Ku, Sheng-Yu, Bakht, Martin K., Borah, Ashir A., Herbert, Zachary T., Tolstorukov, Michael Y., Barbie, David A., Rickman, David S., Brown, Myles, Beltran, Himisha
Published in Nature communications (08.08.2024)
Published in Nature communications (08.08.2024)
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Akt regulates drug-induced cell death through Bcl-w downregulation
Garofalo, Michela, Quintavalle, Cristina, Zanca, Ciro, De Rienzo, Assunta, Romano, Giulia, Acunzo, Mario, Puca, Loredana, Incoronato, Mariarosaria, Croce, Carlo M, Condorelli, Gerolama
Published in PloS one (30.12.2008)
Published in PloS one (30.12.2008)
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N-Myc-mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer
Berger, Adeline, Brady, Nicholas J, Bareja, Rohan, Robinson, Brian, Conteduca, Vincenza, Augello, Michael A, Puca, Loredana, Ahmed, Adnan, Dardenne, Etienne, Lu, Xiaodong, Hwang, Inah, Bagadion, Alyssa M, Sboner, Andrea, Elemento, Olivier, Paik, Jihye, Yu, Jindan, Barbieri, Christopher E, Dephoure, Noah, Beltran, Himisha, Rickman, David S
Published in The Journal of clinical investigation (01.09.2019)
Published in The Journal of clinical investigation (01.09.2019)
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A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers
Beltran, Himisha, Oromendia, Clara, Danila, Daniel C, Montgomery, Bruce, Hoimes, Christopher, Szmulewitz, Russell Z, Vaishampayan, Ulka, Armstrong, Andrew J, Stein, Mark, Pinski, Jacek, Mosquera, Juan M, Sailer, Verena, Bareja, Rohan, Romanel, Alessandro, Gumpeni, Naveen, Sboner, Andrea, Dardenne, Etienne, Puca, Loredana, Prandi, Davide, Rubin, Mark A, Scher, Howard I, Rickman, David S, Demichelis, Francesca, Nanus, David M, Ballman, Karla V, Tagawa, Scott T
Published in Clinical cancer research (01.01.2019)
Published in Clinical cancer research (01.01.2019)
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Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer
Puca, Loredana, Gavyert, Katie, Sailer, Verena, Conteduca, Vincenza, Dardenne, Etienne, Sigouros, Michael, Isse, Kumiko, Kearney, Megan, Vosoughi, Aram, Fernandez, Luisa, Pan, Heng, Motanagh, Samaneh, Hess, Judy, Donoghue, Adam J, Sboner, Andrea, Wang, Yuzhuo, Dittamore, Ryan, Rickman, David, Nanus, David M, Tagawa, Scott T, Elemento, Olivier, Mosquera, Juan Miguel, Saunders, Laura, Beltran, Himisha
Published in Science translational medicine (20.03.2019)
Published in Science translational medicine (20.03.2019)
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Α-arrestin 1 (ARRDC1) and β-arrestins cooperate to mediate Notch degradation in mammals
Puca, Loredana, Chastagner, Patricia, Meas-Yedid, Vannary, Israël, Alain, Brou, Christel
Published in Journal of cell science (01.10.2013)
Published in Journal of cell science (01.10.2013)
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Extracellular Matrix in Synthetic Hydrogel‐Based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 Inhibitors
Mosquera, Matthew J., Kim, Sungwoong, Bareja, Rohan, Fang, Zhou, Cai, Shuangyi, Pan, Heng, Asad, Muhammad, Martin, Maria Laura, Sigouros, Michael, Rowdo, Florencia M., Ackermann, Sarah, Capuano, Jared, Bernheim, Jacob, Cheung, Cynthia, Doane, Ashley, Brady, Nicholas, Singh, Richa, Rickman, David S., Prabhu, Varun, Allen, Joshua E., Puca, Loredana, Coskun, Ahmet F., Rubin, Mark A., Beltran, Himisha, Mosquera, Juan Miguel, Elemento, Olivier, Singh, Ankur
Published in Advanced materials (Weinheim) (01.01.2022)
Published in Advanced materials (Weinheim) (01.01.2022)
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Notch signaling suppresses neuroendocrine differentiation and alters the immune microenvironment in advanced prostate cancer
Ku, Sheng-Yu, Wang, Yanqing, Garcia, Maria Mica, Yamada, Yasutaka, Mizuno, Kei, Long, Mark D, Rosario, Spencer, Chinnam, Meenalakshmi, Al Assaad, Majd, Puca, Loredana, Kim, Min Jin, Bakht, Martin K, Venkadakrishnan, Varadha Balaji, Robinson, Brian D, Acosta, Andrés M, Wadosky, Kristine M, Mosquera, Juan Miguel, Goodrich, David W, Beltran, Himisha
Published in The Journal of clinical investigation (01.09.2024)
Published in The Journal of clinical investigation (01.09.2024)
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