Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region
Schlepckow, Kai, Monroe, Kathryn M, Kleinberger, Gernot, Cantuti‐Castelvetri, Ludovico, Parhizkar, Samira, Xia, Dan, Willem, Michael, Werner, Georg, Pettkus, Nadine, Brunner, Bettina, Sülzen, Alice, Nuscher, Brigitte, Hampel, Heike, Xiang, Xianyuan, Feederle, Regina, Tahirovic, Sabina, Park, Joshua I, Prorok, Rachel, Mahon, Cathal, Liang, Chun‐Chi, Shi, Ju, Kim, Do Jin, Sabelström, Hanna, Huang, Fen, Di Paolo, Gilbert, Simons, Mikael, Lewcock, Joseph W, Haass, Christian
Published in EMBO molecular medicine (07.04.2020)
Published in EMBO molecular medicine (07.04.2020)
Get full text
Journal Article
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic
Logan, Todd, Simon, Matthew J., Rana, Anil, Cherf, Gerald M., Srivastava, Ankita, Davis, Sonnet S., Low, Ray Lieh Yoon, Chiu, Chi-Lu, Fang, Meng, Huang, Fen, Bhalla, Akhil, Llapashtica, Ceyda, Prorok, Rachel, Pizzo, Michelle E., Calvert, Meredith E.K., Sun, Elizabeth W., Hsiao-Nakamoto, Jennifer, Rajendra, Yashas, Lexa, Katrina W., Srivastava, Devendra B., van Lengerich, Bettina, Wang, Junhua, Robles-Colmenares, Yaneth, Kim, Do Jin, Duque, Joseph, Lenser, Melina, Earr, Timothy K., Nguyen, Hoang, Chau, Roni, Tsogtbaatar, Buyankhishig, Ravi, Ritesh, Skuja, Lukas L., Solanoy, Hilda, Rosen, Howard J., Boeve, Bradley F., Boxer, Adam L., Heuer, Hilary W., Dennis, Mark S., Kariolis, Mihalis S., Monroe, Kathryn M., Przybyla, Laralynne, Sanchez, Pascal E., Meisner, Rene, Diaz, Dolores, Henne, Kirk R., Watts, Ryan J., Henry, Anastasia G., Gunasekaran, Kannan, Astarita, Giuseppe, Suh, Jung H., Lewcock, Joseph W., DeVos, Sarah L., Di Paolo, Gilbert
Published in Cell (02.09.2021)
Published in Cell (02.09.2021)
Get full text
Journal Article
A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models
van Lengerich, Bettina, Zhan, Lihong, Xia, Dan, Chan, Darren, Joy, David, Park, Joshua I., Tatarakis, David, Calvert, Meredith, Hummel, Selina, Lianoglou, Steve, Pizzo, Michelle E., Prorok, Rachel, Thomsen, Elliot, Bartos, Laura M., Beumers, Philipp, Capell, Anja, Davis, Sonnet S., de Weerd, Lis, Dugas, Jason C., Duque, Joseph, Earr, Timothy, Gadkar, Kapil, Giese, Tina, Gill, Audrey, Gnörich, Johannes, Ha, Connie, Kannuswamy, Malavika, Kim, Do Jin, Kunte, Sebastian T., Kunze, Lea H., Lac, Diana, Lechtenberg, Kendra, Leung, Amy Wing-Sze, Liang, Chun-Chi, Lopez, Isabel, McQuade, Paul, Modi, Anuja, Torres, Vanessa O., Nguyen, Hoang N., Pesämaa, Ida, Propson, Nicholas, Reich, Marvin, Robles-Colmenares, Yaneth, Schlepckow, Kai, Slemann, Luna, Solanoy, Hilda, Suh, Jung H., Thorne, Robert G., Vieira, Chandler, Wind-Mark, Karin, Xiong, Ken, Zuchero, Y. Joy Yu, Diaz, Dolo, Dennis, Mark S., Huang, Fen, Scearce-Levie, Kimberly, Watts, Ryan J., Haass, Christian, Lewcock, Joseph W., Di Paolo, Gilbert, Brendel, Matthias, Sanchez, Pascal E., Monroe, Kathryn M.
Published in Nature neuroscience (01.03.2023)
Published in Nature neuroscience (01.03.2023)
Get full text
Journal Article
INNV-24. PATIENT SATISFACTION AND COST ANALYSIS OF THE TELEMEDICINE PROGRAM WITHIN A NEURO-ONCOLOGY PROGRAM
Bilenkin, Arkady, Kang, Richard, Prorok, Rachel, Rogers, Andrea, Naso, Cristina, Patel, Krupal, Beer-Furlan, Andre, Liu, James
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Get full text
Journal Article
Patient satisfaction and cost savings analysis of the telemedicine program within a neuro-oncology department
Liu, James K. C., Kang, Richard, Bilenkin, Arkady, Prorok, Rachel, Whiting, Junmin, Patel, Krupal B., Beer-Furlan, Andre, Naso, Cristina, Rogers, Andrea, Castro, Xavier Baez, Peguero, Edwin, Mokhtari, Sepideh, Tran, Nam, Etame, Arnold, Pina, Yolanda, Spiess, Philippe E., Forsyth, Peter, Vogelbaum, Michael A.
Published in Journal of neuro-oncology (01.11.2022)
Published in Journal of neuro-oncology (01.11.2022)
Get full text
Journal Article
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic
Logan, Todd, Simon, Matthew J., Rana, Anil, Cherf, Gerald M., Srivastava, Ankita, Davis, Sonnet S., Yoon Low, Ray Lieh, Chiu, Chi-Lu, Fang, Meng, Huang, Fen, Bhalla, Akhil, Llapashtica, Ceyda, Prorok, Rachel, Pizzo, Michelle E., Calvert, Meredith E.K., Sun, Elizabeth W., Hsiao-Nakamoto, Jennifer, Rajendra, Yashas, Lexa, Katrina W., Srivastava, Devendra B., van Lengerich, Bettina, Wang, Junhua, Robles-Colmenares, Yaneth, Kim, Do Jin, Duque, Joseph, Lenser, Melina, Earr, Timothy K., Nguyen, Hoang, Chau, Roni, Tsogtbaatar, Buyankhishig, Ravi, Ritesh, Skuja, Lukas L., Solanoy, Hilda, Rosen, Howard J., Boeve, Bradley F., Boxer, Adam L., Heuer, Hilary W., Dennis, Mark S., Kariolis, Mihalis S., Monroe, Kathryn M., Przybyla, Laralynne, Sanchez, Pascal E., Meisner, Rene, Diaz, Dolores, Henne, Kirk R., Watts, Ryan J., Henry, Anastasia G., Gunasekaran, Kannan, Astarita, Giuseppe, Suh, Jung H., Lewcock, Joseph W., DeVos, Sarah L., Di Paolo, Gilbert
Published in Cell (14.03.2024)
Published in Cell (14.03.2024)
Get full text
Journal Article
프로그라눌린 변이체들
LOW RAY L.Y, PROROK RACHEL, CHERF GERALD MAXWELL, KANNAN GUNASEKARAN, SRIVASTAVA ANKITA, LEXA KATRINA W
Year of Publication 27.09.2022
Get full text
Year of Publication 27.09.2022
Patent
항-TREM2 항체 및 이의 사용 방법
GU ZHENYU, MONROE KATHRYN M, PARK JOSHUA I, PROROK RACHEL, DENNIS MARK S, MAHON CATHAL S, VAN LENGERICH BETTINA, SILVERMAN ADAM P, KARIOLIS MIHALIS S
Year of Publication 27.09.2022
Get full text
Year of Publication 27.09.2022
Patent
A brain penetrant progranulin biotherapeutic rescues lysosomal and inflammatory phenotypes in the brain of GRN knockout mice: Lipids in AD and FTD: From genes to interventions
Logan, Todd, DeVos, Sarah, Simon, Matthew J., Davis, Sonnet, Wang, Junhua, Low, Ray, Huang, Fen, Rajendra, Yashas, Prorok, Rachel, Sun, Elizabeth, Rana, Anil, Hsiao‐Nakamoto, Jennifer, Mosesova, Sofia, Zhu, Yuda, Cherf, Gerald M., Lengerich, Bettina, Bhalla, Akhil, Kim, Do Jin, Chan, Darren, Duque, Joseph, Tran, Hai, Lenser, Melina, Nguyen, Hoang, Chau, Roni, Earr, Timothy, Kariolis, Mihalis S., Monroe, Kathryn M., Sanchez, Pascal E., Dennis, Mark S., Henne, Kirk R., Gunasekaran, Kannan, Astarita, Giuseppe, Watts, Ryan J., Sweeney, Zachary K., Lewcock, Joseph W., Srivastava, Ankita, Di Paolo, Gilbert
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
Get full text
Journal Article
A brain penetrant progranulin biotherapeutic rescues lysosomal and inflammatory phenotypes in the brain of GRN knockout mice
Logan, Todd, DeVos, Sarah, Simon, Matthew J., Davis, Sonnet, Wang, Junhua, Low, Ray, Huang, Fen, Rajendra, Yashas, Prorok, Rachel, Sun, Elizabeth, Rana, Anil, Hsiao‐Nakamoto, Jennifer, Mosesova, Sofia, Zhu, Yuda, Cherf, Gerald M., Lengerich, Bettina, Bhalla, Akhil, Kim, Do Jin, Chan, Darren, Duque, Joseph, Tran, Hai, Lenser, Melina, Nguyen, Hoang, Chau, Roni, Earr, Timothy, Kariolis, Mihalis S., Monroe, Kathryn M., Sanchez, Pascal E., Dennis, Mark S., Henne, Kirk R., Gunasekaran, Kannan, Astarita, Giuseppe, Watts, Ryan J., Sweeney, Zachary K., Lewcock, Joseph W., Srivastava, Ankita, Di Paolo, Gilbert
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
Get full text
Journal Article
Enhancing protective microglial activities with a dual function TREM 2 antibody to the stalk region
Schlepckow, Kai, Monroe, Kathryn M, Kleinberger, Gernot, Ludovico Cantuti‐Castelvetri, Parhizkar, Samira, Xia, Dan, Willem, Michael, Werner, Georg, Pettkus, Nadine, Brunner, Bettina, Sülzen, Alice, Nuscher, Brigitte, Hampel, Heike, Xiang, Xianyuan, Feederle, Regina, Tahirovic, Sabina, Park, Joshua I, Prorok, Rachel, Mahon, Cathal, Chun‐Chi Liang, Shi, Ju, Do Jin Kim, Sabelström, Hanna, Huang, Fen, Gilbert Di Paolo, Simons, Mikael, Lewcock, Joseph W, Haass, Christian
Published in EMBO molecular medicine (07.04.2020)
Published in EMBO molecular medicine (07.04.2020)
Get full text
Journal Article
Progranulin variants
PROROK, Rachel, KANNAN, Gunasekaran, SRIVASTAVA, Ankita, LOW, Ray L.Y, CHERF, Gerald Maxwell, LEXA, Katrina W
Year of Publication 21.12.2023
Get full text
Year of Publication 21.12.2023
Patent
PROGRANULIN VARIANTS
Lexa, Katrina W, Kannan, Gunasekaran, Low, Ray L. Y, Prorok, Rachel, Srivastava, Ankita, Cherf, Gerald Maxwell
Year of Publication 24.08.2023
Get full text
Year of Publication 24.08.2023
Patent
Progranulin variants
Lexa, Katrina W, Kannan, Gunasekaran, Low, Ray L. Y, Prorok, Rachel, Srivastava, Ankita, Cherf, Gerald Maxwell
Year of Publication 09.05.2023
Get full text
Year of Publication 09.05.2023
Patent
PROGRANULIN VARIANTS
PROROK, Rachel, KANNAN, Gunasekaran, SRIVASTAVA, Ankita, LOW, Ray L.Y, CHERF, Gerald Maxwell, LEXA, Katrina W
Year of Publication 02.11.2022
Get full text
Year of Publication 02.11.2022
Patent
PROGRANULIN VARIANTS
Lexa, Katrina W, Low, Ray L.Y, Kannan, Gunasekaran, Prorok, Rachel, Srivastava, Ankita, Cherf, Gerald Maxwell
Year of Publication 14.07.2022
Get full text
Year of Publication 14.07.2022
Patent
PROGRANULIN VARIANTS
Lexa, Katrina W, Low, Ray L.Y, Kannan, Gunasekaran, Prorok, Rachel, Srivastava, Ankita, Cherf, Gerald Maxwell
Year of Publication 07.07.2022
Get full text
Year of Publication 07.07.2022
Patent
Progranulin variants
PROROK, Rachel, KANNAN, Gunasekaran, SRIVASTAVA, Ankita, LOW, Ray L.Y, CHERF, Gerald Maxwell, LEXA, Katrina W
Year of Publication 30.06.2022
Get full text
Year of Publication 30.06.2022
Patent
PROGRANULIN VARIANTS
KANNAN, GUNASEKARAN, LEXA, KATRINA W, LOW, RAY L.Y, CHERF, GERALD MAXWELL, PROROK, RACHEL, SRIVASTAVA, ANKITA
Year of Publication 01.07.2021
Get full text
Year of Publication 01.07.2021
Patent
PROGRANULIN VARIANTS
PROROK, Rachel, KANNAN, Gunasekaran, SRIVASTAVA, Ankita, LOW, Ray L.Y, CHERF, Gerald Maxwell, LEXA, Katrina W
Year of Publication 01.07.2021
Get full text
Year of Publication 01.07.2021
Patent