Strategies for Stabilization of Enzymes in Organic Solvents
Stepankova, Veronika, Bidmanova, Sarka, Koudelakova, Tana, Prokop, Zbynek, Chaloupkova, Radka, Damborsky, Jiri
Published in ACS catalysis (06.12.2013)
Published in ACS catalysis (06.12.2013)
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Engineering the protein dynamics of an ancestral luciferase
Schenkmayerova, Andrea, Pinto, Gaspar P., Toul, Martin, Marek, Martin, Hernychova, Lenka, Planas-Iglesias, Joan, Daniel Liskova, Veronika, Pluskal, Daniel, Vasina, Michal, Emond, Stephane, Dörr, Mark, Chaloupkova, Radka, Bednar, David, Prokop, Zbynek, Hollfelder, Florian, Bornscheuer, Uwe T., Damborsky, Jiri
Published in Nature communications (14.06.2021)
Published in Nature communications (14.06.2021)
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FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants
Bednar, David, Beerens, Koen, Sebestova, Eva, Bendl, Jaroslav, Khare, Sagar, Chaloupkova, Radka, Prokop, Zbynek, Brezovsky, Jan, Baker, David, Damborsky, Jiri
Published in PLoS computational biology (01.11.2015)
Published in PLoS computational biology (01.11.2015)
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Exploring the challenges of computational enzyme design by rebuilding the active site of a dehalogenase
Jindal, Garima, Slanska, Katerina, Kolev, Veselin, Damborsky, Jiri, Prokop, Zbynek, Warshel, Arieh
Published in Proceedings of the National Academy of Sciences - PNAS (08.01.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (08.01.2019)
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Exacerbation of substrate toxicity by IPTG in Escherichia coli BL21(DE3) carrying a synthetic metabolic pathway
Dvorak, Pavel, Chrast, Lukas, Nikel, Pablo I, Fedr, Radek, Soucek, Karel, Sedlackova, Miroslava, Chaloupkova, Radka, de Lorenzo, Víctor, Prokop, Zbynek, Damborsky, Jiri
Published in Microbial cell factories (21.12.2015)
Published in Microbial cell factories (21.12.2015)
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Impact of the access tunnel engineering on catalysis is strictly ligand‐specific
Kaushik, Shubhangi, Marques, Sérgio M., Khirsariya, Prashant, Paruch, Kamil, Libichova, Lenka, Brezovsky, Jan, Prokop, Zbynek, Chaloupkova, Radka, Damborsky, Jiri
Published in The FEBS journal (01.04.2018)
Published in The FEBS journal (01.04.2018)
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Substrate inhibition by the blockage of product release and its control by tunnel engineering
Kokkonen, Piia, Beier, Andy, Mazurenko, Stanislav, Damborsky, Jiri, Bednar, David, Prokop, Zbynek
Published in RSC chemical biology (01.04.2021)
Published in RSC chemical biology (01.04.2021)
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Haloalkane dehalogenases: biotechnological applications
Koudelakova, Tana, Bidmanova, Sarka, Dvorak, Pavel, Pavelka, Antonin, Chaloupkova, Radka, Prokop, Zbynek, Damborsky, Jiri
Published in Biotechnology journal (01.01.2013)
Published in Biotechnology journal (01.01.2013)
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Recognition and coacervation of G-quadruplexes by a multifunctional disordered region in RECQ4 helicase
Papageorgiou, Anna C., Pospisilova, Michaela, Cibulka, Jakub, Ashraf, Raghib, Waudby, Christopher A., Kadeřávek, Pavel, Maroz, Volha, Kubicek, Karel, Prokop, Zbynek, Krejci, Lumir, Tripsianes, Konstantinos
Published in Nature communications (24.10.2023)
Published in Nature communications (24.10.2023)
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Illuminating the mechanism and allosteric behavior of NanoLuc luciferase
Nemergut, Michal, Pluskal, Daniel, Horackova, Jana, Sustrova, Tereza, Tulis, Jan, Barta, Tomas, Baatallah, Racha, Gagnot, Glwadys, Novakova, Veronika, Majerova, Marika, Sedlackova, Karolina, Marques, Sérgio M., Toul, Martin, Damborsky, Jiri, Prokop, Zbynek, Bednar, David, Janin, Yves L., Marek, Martin
Published in Nature communications (29.11.2023)
Published in Nature communications (29.11.2023)
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A closed 3D printed microfluidic device for automated growth and differentiation of cerebral organoids from single-cell suspension
Kandra, Mario, Vanova, Tereza, Jongen, Vincent A, Pospíšil, Jakub, Novák, Josef, Chochola, Václav, Buryška, Tomáš, Prokop, Zbyněk, Hodný, Zdeněk, Hampl, Ales, Bohaciakova, Dasa, Jaros, Josef
Published in Biotechnology journal (01.08.2024)
Published in Biotechnology journal (01.08.2024)
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Protection of Arabidopsis Blunt-Ended Telomeres Is Mediated by a Physical Association with the Ku Heterodimer
Valuchova, Sona, Fulnecek, Jaroslav, Prokop, Zbynek, Stolt-Bergner, Peggy, Janouskova, Eliska, Hofr, Ctirad, Riha, Karel
Published in The Plant cell (01.06.2017)
Published in The Plant cell (01.06.2017)
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A Single Mutation in a Tunnel to the Active Site Changes the Mechanism and Kinetics of Product Release in Haloalkane Dehalogenase LinB
Biedermannová, Lada, Prokop, Zbyněk, Gora, Artur, Chovancová, Eva, Kovács, Mihály, Damborský, Jiří, Wade, Rebecca C.
Published in The Journal of biological chemistry (17.08.2012)
Published in The Journal of biological chemistry (17.08.2012)
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Sensitive operation of enzyme-based biodevices by advanced signal processing
Mazurenko, Stanislav, Bidmanova, Sarka, Kotlanova, Marketa, Damborsky, Jiri, Prokop, Zbynek
Published in PloS one (18.06.2018)
Published in PloS one (18.06.2018)
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Journal Article
Engineering Enzyme Stability and Resistance to an Organic Cosolvent by Modification of Residues in the Access Tunnel
Koudelakova, Tana, Chaloupkova, Radka, Brezovsky, Jan, Prokop, Zbynek, Sebestova, Eva, Hesseler, Martin, Khabiri, Morteza, Plevaka, Maryia, Kulik, Daryna, Kuta Smatanova, Ivana, Rezacova, Pavlina, Ettrich, Rudiger, Bornscheuer, Uwe T., Damborsky, Jiri
Published in Angewandte Chemie International Edition (11.02.2013)
Published in Angewandte Chemie International Edition (11.02.2013)
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The dynamics of xylem sap pH under drought: a universal response in herbs?
Gloser, Vít, Korovetska, Halyna, Martín-Vertedor, Ana Isabel, Hájíčková, Martina, Prokop, Zbyněk, Wilkinson, Sally, Davies, William
Published in Plant and soil (01.12.2016)
Published in Plant and soil (01.12.2016)
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Evolutionary Analysis As a Powerful Complement to Energy Calculations for Protein Stabilization
Beerens, Koen, Mazurenko, Stanislav, Kunka, Antonin, Marques, Sergio M, Hansen, Niels, Musil, Milos, Chaloupkova, Radka, Waterman, Jitka, Brezovsky, Jan, Bednar, David, Prokop, Zbynek, Damborsky, Jiri
Published in ACS catalysis (05.10.2018)
Published in ACS catalysis (05.10.2018)
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Journal Article
Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate
Nemergut, Michal, Marques, Sérgio M, Uhrik, Lukas, Vanova, Tereza, Nezvedova, Marketa, Gadara, Darshak Chandulal, Jha, Durga, Tulis, Jan, Novakova, Veronika, Planas-Iglesias, Joan, Kunka, Antonin, Legrand, Anthony, Hribkova, Hana, Pospisilova, Veronika, Sedmik, Jiri, Raska, Jan, Prokop, Zbynek, Damborsky, Jiri, Bohaciakova, Dasa, Spacil, Zdenek, Hernychova, Lenka, Bednar, David, Marek, Martin
Published in Molecular neurodegeneration (06.06.2023)
Published in Molecular neurodegeneration (06.06.2023)
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