Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
PRESTA, L. G, CHEN, H, O'CONNOR, S. J, CHISHOLM, V, MENG, Y. G, KRUMMEN, L, WINKLER, M, FERRARA, N
Published in Cancer research (Chicago, Ill.) (15.10.1997)
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Published in Cancer research (Chicago, Ill.) (15.10.1997)
Journal Article
An efficient route to human bispecific IgG
Merchant, A. Margaret, Zhu, Zhenping, Yuan, Jean Q, Goddard, Audrey, Adams, Camellia W, Presta, Leonard G, Carter, Paul
Published in Nature biotechnology (01.07.1998)
Published in Nature biotechnology (01.07.1998)
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Journal Article
Humanization of an antibody directed against IgE
Presta, LG, Lahr, SJ, Shields, RL, Porter, JP, Gorman, CM, Fendly, BM, Jardieu, PM
Published in The Journal of immunology (1950) (01.09.1993)
Published in The Journal of immunology (1950) (01.09.1993)
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Journal Article
Generation of an LFA-1 Antagonist by the Transfer of the ICAM-1 Immunoregulatory Epitope to a Small Molecule
Gadek, T. R., Burdick, D. J., McDowell, R. S., Stanley, M. S., Marsters, J. C., Paris, K. J., Oare, D. A., Reynolds, M. E., Ladner, C., Zioncheck, K. A., Lee, W. P., Gribling, P., Dennis, M. S., Skelton, N. J., Tumas, D. B., Clark, K. R., Keating, S. M., Beresini, M. H., Tilley, J. W., Presta, L. G., Bodary, S. C.
Published in Science (American Association for the Advancement of Science) (08.02.2002)
Published in Science (American Association for the Advancement of Science) (08.02.2002)
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Journal Article
Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease
Petkova, Stefka B., Akilesh, Shreeram, Sproule, Thomas J., Christianson, Gregory J., Al Khabbaz, Hana, Brown, Aaron C., Presta, Leonard G., Meng, Y. Gloria, Roopenian, Derry C.
Published in International immunology (01.12.2006)
Published in International immunology (01.12.2006)
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Journal Article
Hydrogen bonding in globular proteins
Sticke, Douglas F., Presta, Leonard G., Dill, Ken A., Rose, George D.
Published in Journal of molecular biology (20.08.1992)
Published in Journal of molecular biology (20.08.1992)
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Journal Article
Engineering therapeutic antibodies for improved function
Presta, L G, Shields, R L, Namenuk, A K, Hong, K, Meng, Y G
Published in Biochemical Society transactions (01.08.2002)
Published in Biochemical Society transactions (01.08.2002)
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Journal Article
Lack of Fucose on Human IgG1 N-Linked Oligosaccharide Improves Binding to Human FcγRIII and Antibody-dependent Cellular Toxicity
Shields, Robert L., Lai, Jadine, Keck, Rodney, O'Connell, Lori Y., Hong, Kyu, Meng, Y. Gloria, Weikert, Stefanie H.A., Presta, Leonard G.
Published in The Journal of biological chemistry (26.07.2002)
Published in The Journal of biological chemistry (26.07.2002)
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Journal Article
Helix Signals in Proteins
Presta, Leonard G., Rose, George D.
Published in Science (American Association for the Advancement of Science) (17.06.1988)
Published in Science (American Association for the Advancement of Science) (17.06.1988)
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Journal Article
P- and E-Selectin Use Common Sites for Carbohydrate Ligand Recognition and Cell Adhesion
Erbe, David V., Watson, Susan R., Presta, Leonard G., Wolitzky, Barry A., Foxall, Carroll, Brandley, Brian K., Lasky, Laurence A.
Published in The Journal of cell biology (01.03.1993)
Published in The Journal of cell biology (01.03.1993)
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Journal Article
Mapping the CD4 Binding Site for Human Immunodeficiency Virus by Alanine- Scanning Mutagenesis
Ashkenazi, Avi, Presta, Leonard G., Marsters, Scot A., Camerato, Thomas R., Rosenthal, Kim A., Fendly, Brian M., Capon, Daniel J.
Published in Proceedings of the National Academy of Sciences - PNAS (01.09.1990)
Published in Proceedings of the National Academy of Sciences - PNAS (01.09.1990)
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Journal Article
High Resolution Mapping of the Binding Site on Human IgG1 for FcγRI, FcγRII, FcγRIII, and FcRn and Design of IgG1 Variants with Improved Binding to the FcγR
Shields, Robert L., Namenuk, Angela K., Hong, Kyu, Meng, Y. Gloria, Rae, Julie, Briggs, John, Xie, Dong, Lai, Jadine, Stadlen, Andrew, Li, Betty, Fox, Judith A., Presta, Leonard G.
Published in The Journal of biological chemistry (02.03.2001)
Published in The Journal of biological chemistry (02.03.2001)
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Journal Article
Remodeling domain interfaces to enhance heterodimer formation
Zhu, Zhenping, Presta, Leonard G., Zapata, Gerardo, Carter, Paul
Published in Protein science (01.04.1997)
Published in Protein science (01.04.1997)
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Journal Article
Mucosal addressin cell adhesion molecule-1: a structural and functional analysis demarcates the integrin binding motif
Viney, JL, Jones, S, Chiu, HH, Lagrimas, B, Renz, ME, Presta, LG, Jackson, D, Hillan, KJ, Lew, S, Fong, S
Published in The Journal of immunology (1950) (15.09.1996)
Published in The Journal of immunology (1950) (15.09.1996)
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Journal Article
Identification of an E-Selectin Region Critical for Carbohydrate Recognition and Cell Adhesion
Erbe, David V., Wolitzky, Barry A., Presta, Leonard G., Norton, Christine R., Ramos, Robert J., Burns, Daniel K., Rumberger, John M., B. N. Narasinga Rao, Foxall, Carrol, Brandley, Brian K., Lasky, Laurence A.
Published in The Journal of cell biology (01.10.1992)
Published in The Journal of cell biology (01.10.1992)
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Journal Article
Mapping of the C1q Binding Site on Rituxan, a Chimeric Antibody with a Human IgG1 Fc
Idusogie, Esohe E, Presta, Leonard G, Gazzano-Santoro, Helene, Totpal, Klara, Wong, Pin Yee, Ultsch, Mark, Meng, Y. Gloria, Mulkerrin, Michael G
Published in The Journal of immunology (1950) (15.04.2000)
Published in The Journal of immunology (1950) (15.04.2000)
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Journal Article
Human FcERI-IgG and humanized anti-IgE monoclonal antibody MaE11 block passive sensitization of human and rhesus monkey lung
Saban, Ricardo, Haak-Frendscho, Mary, Zine, Matthew, Ridgway, John, Gorman, Cornelia, Presta, Leonard G., Bjorling, Dale, Saban, Marcia, Jardieu, Paula
Published in Journal of allergy and clinical immunology (01.11.1994)
Published in Journal of allergy and clinical immunology (01.11.1994)
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