Selective targeting of the IL23 pathway: Generation and characterization of a novel high-affinity humanized anti-IL23A antibody
Singh, Sanjaya, Kroe-Barrett, Rachel R, Canada, Keith A, Zhu, Xiang, Sepulveda, Eliud, Wu, Helen, He, Yaqin, Raymond, Ernest L, Ahlberg, Jennifer, Frego, Lee E, Amodeo, Laura M, Catron, Katrina M, Presky, David H, Hanke, Jeffrey H
Published in mAbs (04.07.2015)
Published in mAbs (04.07.2015)
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Unexpected Potency Differences between B-Cell-Activating Factor (BAFF) Antagonist Antibodies against Various Forms of BAFF: Trimer, 60-Mer, and Membrane-Bound
Nicoletti, Amy M, Kenny, Cynthia Hess, Khalil, Ashraf M, Pan, Qi, Ralph, Kerry L M, Ritchie, Julie, Venkataramani, Sathyadevi, Presky, David H, DeWire, Scott M, Brodeur, Scott R
Published in The Journal of pharmacology and experimental therapeutics (01.10.2016)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2016)
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A Functional Interleukin 12 Receptor Complex is Composed of Two β -type Cytokine Receptor Subunits
Presky, David H., Yang, Hong, Minetti, Lisa J., Chua, Anne O., Nabavi, Nasrin, Wu, Chang-You, Gately, Maurice K., Gubler, Ueli
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.1996)
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.1996)
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The Role of Stat4 in Species-Specific Regulation of Th Cell Development by Type I IFNs
Rogge, Lars, D'Ambrosio, Daniele, Biffi, Mauro, Penna, Giuseppe, Minetti, Lisa J, Presky, David H, Adorini, Luciano, Sinigaglia, Francesco
Published in The Journal of immunology (1950) (15.12.1998)
Published in The Journal of immunology (1950) (15.12.1998)
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Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains
Graves, Bradford J, Crowther, Robert L, Chandran, Chitra, Rumberger, John M, Li, Shirley, Huang, Kuo-Sen, Presky, David H, Familletti, Philip C, Wolitzky, Barry A, Burns, Daniel K
Published in Nature (London) (10.02.1994)
Published in Nature (London) (10.02.1994)
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IL-12 Receptor β2 (IL-12Rβ2)-Deficient Mice Are Defective in IL-12-Mediated Signaling Despite the Presence of High Affinity IL-12 Binding Sites
Wu, Chang-you, Wang, Xin, Gadina, Massimo, O’Shea, John J., Presky, David H., Magram, Jeanne
Published in The Journal of immunology (1950) (01.12.2000)
Published in The Journal of immunology (1950) (01.12.2000)
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Suppression of CD4 + T cell activation by a novel inhibitor of Src family kinases
McRae, Bradford L., Wallace, Craig, Dixon, Kathleen Fitzgerald, Roux, Alyson, Mohan, Sukumari, Jia, Yong, Presky, David H., Tracey, Daniel E., Hirst, Gavin C.
Published in International immunopharmacology (01.04.2005)
Published in International immunopharmacology (01.04.2005)
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Journal Article
Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist
Gillessen, S, Carvajal, D, Ling, P, Podlaski, F J, Stremlo, D L, Familletti, P C, Gubler, U, Presky, D H, Stern, A S, Gately, M K
Published in European journal of immunology (01.01.1995)
Published in European journal of immunology (01.01.1995)
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Analysis of the Multiple Interactions Between IL-12 and the High Affinity IL-12 Receptor Complex
Presky, David H, Minetti, Lisa J, Gillessen, Silke, Wilkinson, Victoria L, Wu, Chang-You, Gubler, Ueli, Chizzonite, Richard, Gately, Maurice K
Published in The Journal of immunology (1950) (01.03.1998)
Published in The Journal of immunology (1950) (01.03.1998)
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Journal Article
An optimally designed anti-human CD40 antibody with potent B cell suppression for the treatment of autoimmune diseases
Wu, Helen Haixia, Ralph, Kerry-Leigh, Sepuldeva, Eliud, Hansen, Gale, Li, Hua, Huang, Zhong-Fu, Liu, Dongmei, Dziegelewski, Michael, Ahlberg, Jennifer, Frego, Lee, Fogal, Steve, van Tongeren, Susan, Grimaldi, Christine, Litzenberger, Tobias, Presky, David, Singh, Sanjaya, Brodeur, Scott, Kroe-Barrett, Rachel
Published in International journal of pharmaceutics (20.11.2021)
Published in International journal of pharmaceutics (20.11.2021)
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Journal Article
Dysregulation of Lymphocyte Interleukin-12 Receptor Expression in Sézary Syndrome
Zaki, Mohamed H., Shane, Ryan B., Geng, Yuemei, Showe, Louise C., Everetts, Suzanne E., Presky, David H., Wysocka, Maria, Moore, Jonni S., Rook, Alain H.
Published in Journal of investigative dermatology (01.07.2001)
Published in Journal of investigative dermatology (01.07.2001)
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Journal Article
Interleukin-12 antagonist activity of mouse interleukin-12 p40 homodimer in vitro and in vivo
Gately, M K, Carvajal, D M, Connaughton, S E, Gillessen, S, Warrier, R R, Kolinsky, K D, Wilkinson, V L, Dwyer, C M, Higgins, Jr, G F, Podlaski, F J, Faherty, D A, Familletti, P C, Stern, A S, Presky, D H
Published in Annals of the New York Academy of Sciences (01.10.1996)
Published in Annals of the New York Academy of Sciences (01.10.1996)
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Journal Article
Identification and Characterization of a Novel Cytokine-inducible Nuclear Protein from Human Endothelial Cells
Chu, W, Burns, D K, Swerlick, R A, Presky, D H
Published in The Journal of biological chemistry (28.04.1995)
Published in The Journal of biological chemistry (28.04.1995)
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Journal Article
Measurement of human and mouse interleukin-12
Gately, Maurice K, Chizzonite, Richard, Presky, David H
Published in Current protocols in immunology (01.05.2001)
Published in Current protocols in immunology (01.05.2001)
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Journal Article
Efficient cotransduction of tumors by multiple herpes simplex vectors: implications for tumor vaccine production
Karpoff, H M, Kooby, D, D'Angelica, M, Mack, J, Presky, D H, Brownlee, M D, Federoff, H, Fong, Y
Published in Cancer gene therapy (01.04.2000)
Published in Cancer gene therapy (01.04.2000)
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Journal Article
Selective expression of an interleukin-12 receptor component by human T helper 1 cells
Rogge, L, Barberis-Maino, L, Biffi, M, Passini, N, Presky, D H, Gubler, U, Sinigaglia, F
Published in The Journal of experimental medicine (03.03.1997)
Published in The Journal of experimental medicine (03.03.1997)
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Experimental granulomatous colitis in mice is abrogated by induction of TGF-beta-mediated oral tolerance
Neurath, M F, Fuss, I, Kelsall, B L, Presky, D H, Waegell, W, Strober, W
Published in The Journal of experimental medicine (01.06.1996)
Published in The Journal of experimental medicine (01.06.1996)
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Journal Article
Antibodies to the IL-12 Receptor β2 Chain Mark Human Th1 But Not Th2 Cells In Vitro and In Vivo
Rogge, Lars, Papi, Alberto, Presky, David H., Biffi, Mauro, Minetti, Lisa J., Miotto, Deborah, Agostini, Carlo, Semenzato, Gianpietro, Fabbri, Leonardo M., Sinigaglia, Francesco
Published in The Journal of immunology (1950) (01.04.1999)
Published in The Journal of immunology (1950) (01.04.1999)
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