In vivo RNA editing of point mutations via RNA-guided adenosine deaminases
Katrekar, Dhruva, Chen, Genghao, Meluzzi, Dario, Ganesh, Ashwin, Worlikar, Atharv, Shih, Yu-Ru, Varghese, Shyni, Mali, Prashant
Published in Nature methods (01.03.2019)
Published in Nature methods (01.03.2019)
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Journal Article
RNA-Guided Human Genome Engineering via Cas9
Mali, Prashant, Yang, Luhan, Esvelt, Kevin M., Aach, John, Guell, Marc, DiCarlo, James E., Norville, Julie E., Church, George M.
Published in Science (American Association for the Advancement of Science) (15.02.2013)
Published in Science (American Association for the Advancement of Science) (15.02.2013)
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Journal Article
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
Mali, Prashant, Aach, John, Stranges, P Benjamin, Esvelt, Kevin M, Moosburner, Mark, Kosuri, Sriram, Yang, Luhan, Church, George M
Published in Nature biotechnology (01.09.2013)
Published in Nature biotechnology (01.09.2013)
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Journal Article
Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
Esvelt, Kevin M, Mali, Prashant, Braff, Jonathan L, Moosburner, Mark, Yaung, Stephanie J, Church, George M
Published in Nature methods (01.11.2013)
Published in Nature methods (01.11.2013)
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Journal Article
Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells
Byrne, Susan M, Ortiz, Luis, Mali, Prashant, Aach, John, Church, George M
Published in Nucleic acids research (18.02.2015)
Published in Nucleic acids research (18.02.2015)
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Journal Article
Highly Multiplexed Subcellular RNA Sequencing in Situ
Lee, Je Hyuk, Daugharthy, Evan R., Scheiman, Jonathan, Kalhor, Reza, Yang, Joyce L., Ferrante, Thomas C., Terry, Richard, Jeanty, Sauveur S. F., Li, Chao, Amamoto, Ryoji, Peters, Derek T., Turczyk, Brian M., Marblestone, Adam H., Inverso, Samuel A., Bernard, Amy, Mali, Prashant, Rios, Xavier, Aach, John, Church, George M.
Published in Science (American Association for the Advancement of Science) (21.03.2014)
Published in Science (American Association for the Advancement of Science) (21.03.2014)
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Journal Article
Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions
Shen, John Paul, Zhao, Dongxin, Sasik, Roman, Luebeck, Jens, Birmingham, Amanda, Bojorquez-Gomez, Ana, Licon, Katherine, Klepper, Kristin, Pekin, Daniel, Beckett, Alex N, Sanchez, Kyle Salinas, Thomas, Alex, Kuo, Chih-Chung, Du, Dan, Roguev, Assen, Lewis, Nathan E, Chang, Aaron N, Kreisberg, Jason F, Krogan, Nevan, Qi, Lei, Ideker, Trey, Mali, Prashant
Published in Nature methods (01.06.2017)
Published in Nature methods (01.06.2017)
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Journal Article
Optimization of scarless human stem cell genome editing
Yang, Luhan, Guell, Marc, Byrne, Susan, Yang, Joyce L, De Los Angeles, Alejandro, Mali, Prashant, Aach, John, Kim-Kiselak, Caroline, Briggs, Adrian W, Rios, Xavier, Huang, Po-Yi, Daley, George, Church, George
Published in Nucleic acids research (01.10.2013)
Published in Nucleic acids research (01.10.2013)
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Journal Article
In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation
Moreno, Ana M., Fu, Xin, Zhu, Jie, Katrekar, Dhruva, Shih, Yu-Ru V., Marlett, John, Cabotaje, Jessica, Tat, Jasmine, Naughton, John, Lisowski, Leszek, Varghese, Shyni, Zhang, Kang, Mali, Prashant
Published in Molecular therapy (05.07.2018)
Published in Molecular therapy (05.07.2018)
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Journal Article
Efficient Generation of Functional Dopaminergic Neurons from Human Induced Pluripotent Stem Cells Under Defined Conditions
Swistowski, Andrzej, Peng, Jun, Liu, Qiuyue, Mali, Prashant, Rao, Mahendra S., Cheng, Linzhao, Zeng, Xianmin
Published in Stem cells (Dayton, Ohio) (01.10.2010)
Published in Stem cells (Dayton, Ohio) (01.10.2010)
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Journal Article
Lineage barcoding in mice with homing CRISPR
Leeper, Kathleen, Kalhor, Kian, Vernet, Andyna, Graveline, Amanda, Church, George M., Mali, Prashant, Kalhor, Reza
Published in Nature protocols (01.04.2021)
Published in Nature protocols (01.04.2021)
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Journal Article
Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures
Chou, Bin-Kuan, Mali, Prashant, Huang, Xiaosong, Ye, Zhaohui, Dowey, Sarah N, Resar, Linda MS, Zou, Chunlin, Zhang, Y Alex, Tong, Jay, Cheng, Linzhao
Published in Cell research (01.03.2011)
Published in Cell research (01.03.2011)
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Journal Article
Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis
Zhao, Dongxin, Badur, Mehmet G., Luebeck, Jens, Magaña, Jose H., Birmingham, Amanda, Sasik, Roman, Ahn, Christopher S., Ideker, Trey, Metallo, Christian M., Mali, Prashant
Published in Molecular cell (15.02.2018)
Published in Molecular cell (15.02.2018)
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Journal Article
Oligonucleotide conjugated multi-functional adeno-associated viruses
Katrekar, Dhruva, Moreno, Ana M., Chen, Genghao, Worlikar, Atharv, Mali, Prashant
Published in Scientific reports (26.02.2018)
Published in Scientific reports (26.02.2018)
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Journal Article
Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts
Mali, Prashant, Ye, Zhaohui, Hommond, Holly H., Yu, Xiaobing, Lin, Jeff, Chen, Guibin, Zou, Jizhong, Cheng, Linzhao
Published in Stem cells (Dayton, Ohio) (01.08.2008)
Published in Stem cells (Dayton, Ohio) (01.08.2008)
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Journal Article