Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma
De Crignis, Elisa, Hossain, Tanvir, Romal, Shahla, Carofiglio, Fabrizia, Moulos, Panagiotis, Khalid, Mir Mubashir, Rao, Shringar, Bazrafshan, Ameneh, Verstegen, Monique Ma, Pourfarzad, Farzin, Koutsothanassis, Christina, Gehart, Helmuth, Kan, Tsung Wai, Palstra, Robert-Jan, Boucher, Charles, IJzermans, Jan Nm, Huch, Meritxell, Boj, Sylvia F, Vries, Robert, Clevers, Hans, van der Laan, Luc Jw, Hatzis, Pantelis, Mahmoudi, Tokameh
Published in eLife (30.07.2021)
Published in eLife (30.07.2021)
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Journal Article
HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers
Stadhouders, Ralph, Aktuna, Suleyman, Thongjuea, Supat, Aghajanirefah, Ali, Pourfarzad, Farzin, van Ijcken, Wilfred, Lenhard, Boris, Rooks, Helen, Best, Steve, Menzel, Stephan, Grosveld, Frank, Thein, Swee Lay, Soler, Eric
Published in The Journal of clinical investigation (01.04.2014)
Published in The Journal of clinical investigation (01.04.2014)
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Journal Article
Dynamic Transcriptome-Proteome Correlation Networks Reveal Human Myeloid Differentiation and Neutrophil-Specific Programming
Hoogendijk, Arie J., Pourfarzad, Farzin, Aarts, Cathelijn E.M., Tool, Anton T.J., Hiemstra, Ida H., Grassi, Luigi, Frontini, Mattia, Meijer, Alexander B., van den Biggelaar, Maartje, Kuijpers, Taco W.
Published in Cell reports (Cambridge) (19.11.2019)
Published in Cell reports (Cambridge) (19.11.2019)
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Journal Article
Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils
Grassi, Luigi, Pourfarzad, Farzin, Ullrich, Sebastian, Merkel, Angelika, Were, Felipe, Carrillo-de-Santa-Pau, Enrique, Yi, Guoqiang, Hiemstra, Ida H., Tool, Anton T.J., Mul, Erik, Perner, Juliane, Janssen-Megens, Eva, Berentsen, Kim, Kerstens, Hinri, Habibi, Ehsan, Gut, Marta, Yaspo, Marie Laure, Linser, Matthias, Lowy, Ernesto, Datta, Avik, Clarke, Laura, Flicek, Paul, Vingron, Martin, Roos, Dirk, van den Berg, Timo K., Heath, Simon, Rico, Daniel, Frontini, Mattia, Kostadima, Myrto, Gut, Ivo, Valencia, Alfonso, Ouwehand, Willem H., Stunnenberg, Hendrik G., Martens, Joost H.A., Kuijpers, Taco W.
Published in Cell reports (Cambridge) (04.09.2018)
Published in Cell reports (Cambridge) (04.09.2018)
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Journal Article
Hydroxyurea responsiveness in β-thalassemic patients is determined by the stress response adaptation of erythroid progenitors and their differentiation propensity
Pourfarzad, Farzin, von Lindern, Marieke, Azarkeivan, Azita, Hou, Jun, Kia, Sima Kheradmand, Esteghamat, Fatemehsadat, van Ijcken, Wilfred, Philipsen, Sjaak, Najmabadi, Hossein, Grosveld, Frank
Published in Haematologica (Roma) (01.05.2013)
Published in Haematologica (Roma) (01.05.2013)
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Journal Article
Five Friends of Methylated Chromatin Target of Protein-Arginine-Methyltransferase[Prmt]-1 (Chtop), a Complex Linking Arginine Methylation to Desumoylation
Fanis, Pavlos, Gillemans, Nynke, Aghajanirefah, Ali, Pourfarzad, Farzin, Demmers, Jeroen, Esteghamat, Fatemehsadat, Vadlamudi, Ratna K., Grosveld, Frank, Philipsen, Sjaak, van Dijk, Thamar B.
Published in Molecular & cellular proteomics (01.11.2012)
Published in Molecular & cellular proteomics (01.11.2012)
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Journal Article
Fetal globin expression is regulated by Friend of Prmt1
van Dijk, Thamar Bryn, Gillemans, Nynke, Pourfarzad, Farzin, van Lom, Kirsten, von Lindern, Marieke, Grosveld, Frank, Philipsen, Sjaak
Published in Blood (18.11.2010)
Published in Blood (18.11.2010)
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Journal Article
RTTN Mutations Link Primary Cilia Function to Organization of the Human Cerebral Cortex
Kheradmand Kia, Sima, Verbeek, Elly, Engelen, Erik, Schot, Rachel, Poot, Raymond A., de Coo, Irenaeus F.M., Lequin, Maarten H., Poulton, Cathryn J., Pourfarzad, Farzin, Grosveld, Frank G., Brehm, António, de Wit, Marie Claire Y., Oegema, Renske, Dobyns, William B., Verheijen, Frans W., Mancini, Grazia M.S.
Published in American journal of human genetics (07.09.2012)
Published in American journal of human genetics (07.09.2012)
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Journal Article
Locus-Specific Proteomics by TChP: Targeted Chromatin Purification
Pourfarzad, Farzin, Aghajanirefah, Ali, de Boer, Ernie, Ten Have, Sara, Bryn van Dijk, Thamar, Kheradmandkia, Sima, Stadhouders, Ralph, Thongjuea, Supat, Soler, Eric, Gillemans, Nynke, von Lindern, Marieke, Demmers, Jeroen, Philipsen, Sjaak, Grosveld, Frank
Published in Cell reports (Cambridge) (01.08.2013)
Published in Cell reports (Cambridge) (01.08.2013)
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Journal Article
Optimal use of tandem biotin and V5 tags in ChIP assays
Kolodziej, Katarzyna E, Pourfarzad, Farzin, de Boer, Ernie, Krpic, Sanja, Grosveld, Frank, Strouboulis, John
Published in BMC molecular biology (05.02.2009)
Published in BMC molecular biology (05.02.2009)
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Journal Article
The DNA binding factor Hmg20b is a repressor of erythroid differentiation
ESTEGHAMAT, Fatemehsadat, BRYN VAN DIJK, Thamar, HOROS, Rastislav, POURFARZAD, Farzin, VON LINDERN, Marieke, PHILIPSEN, Sjaak, BRAUN, Harald, DEKKER, Sylvia, VAN DER LINDEN, Reinier, HOU, Jun, FANIS, Pavlos, DEMMERS, Jeroen, VAN IJCKEN, Wilfred, OZGÜR, Zeliha
Published in Haematologica (Roma) (01.09.2011)
Published in Haematologica (Roma) (01.09.2011)
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Journal Article
EZH2-dependent chromatin looping controls INK4a and INK4b, but not ARF, during human progenitor cell differentiation and cellular senescence
Kheradmand Kia, Sima, Solaimani Kartalaei, Parham, Farahbakhshian, Elnaz, Pourfarzad, Farzin, von Lindern, Marieke, Verrijzer, C Peter
Published in Epigenetics & chromatin (02.12.2009)
Published in Epigenetics & chromatin (02.12.2009)
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Journal Article
The Cypriot and Iranian National Mutation Frequency Databases
Kleanthous, Marina, Patsalis, Philippos C., Drousiotou, Anthi, Motazacker, Mehdi, Christodoulou, Kyproula, Cariolou, Marios, Baysal, Erol, Khrizi, Kimia, Moghimi, Babak, Pourfarzad, Farzin, van Baal, Sjozef, Deltas, Constantinos, Najmabadi, Hossein, Patrinos, George P.
Published in Human mutation (01.06.2006)
Published in Human mutation (01.06.2006)
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Journal Article
Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells
Chen, Lu, Ge, Bing, Casale, Francesco Paolo, Vasquez, Louella, Kwan, Tony, Garrido-Martín, Diego, Watt, Stephen, Yan, Ying, Kundu, Kousik, Ecker, Simone, Datta, Avik, Richardson, David, Burden, Frances, Mead, Daniel, Mann, Alice L., Fernandez, Jose Maria, Rowlston, Sophia, Wilder, Steven P., Farrow, Samantha, Shao, Xiaojian, Lambourne, John J., Redensek, Adriana, Albers, Cornelis A., Amstislavskiy, Vyacheslav, Ashford, Sofie, Berentsen, Kim, Bomba, Lorenzo, Bourque, Guillaume, Bujold, David, Busche, Stephan, Caron, Maxime, Chen, Shu-Huang, Cheung, Warren, Delaneau, Oliver, Dermitzakis, Emmanouil T., Elding, Heather, Colgiu, Irina, Bagger, Frederik O., Flicek, Paul, Habibi, Ehsan, Iotchkova, Valentina, Janssen-Megens, Eva, Kim, Bowon, Lehrach, Hans, Lowy, Ernesto, Mandoli, Amit, Matarese, Filomena, Maurano, Matthew T., Morris, John A., Pancaldi, Vera, Pourfarzad, Farzin, Rehnstrom, Karola, Rendon, Augusto, Risch, Thomas, Sharifi, Nilofar, Simon, Marie-Michelle, Sultan, Marc, Valencia, Alfonso, Walter, Klaudia, Wang, Shuang-Yin, Frontini, Mattia, Antonarakis, Stylianos E., Clarke, Laura, Yaspo, Marie-Laure, Beck, Stephan, Guigo, Roderic, Rico, Daniel, Martens, Joost H.A., Ouwehand, Willem H., Kuijpers, Taco W., Paul, Dirk S., Stunnenberg, Hendrik G., Stegle, Oliver, Downes, Kate, Pastinen, Tomi, Soranzo, Nicole
Published in Cell (17.11.2016)
Published in Cell (17.11.2016)
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Journal Article
Abstract 2977: Organoid-T-cell co-cultures for preclinical testing of adoptive cell and cancer immunotherapy
Hombrink, Pleun, Mardpour, Soura, Spaan, Ewout, Hanrath, Jarmil, Pourfarzad, Farzin, Mullenders, Jasper, Overmeer, Rene, Robert, G.J, Vries, Sylvia, F, Boj
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier
Jelinsky, Scott A, Derksen, Merel, Bauman, Eric, Verissimo, Carla S, van Dooremalen, Wies T M, Roos, Jamie Lee, Higuera Barón, Celia, Caballero-Franco, Celia, Johnson, Bryce G, Rooks, Michelle G, Pott, Johanna, Oldenburg, Bas, Vries, Robert G J, Boj, Sylvia F, Kasaian, Marion T, Pourfarzad, Farzin, Rosadini, Charles V
Published in Inflammatory bowel diseases (01.02.2023)
Published in Inflammatory bowel diseases (01.02.2023)
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Journal Article
Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types
Ecker, Simone, Chen, Lu, Pancaldi, Vera, Bagger, Frederik O, Fernández, José María, Carrillo de Santa Pau, Enrique, Juan, David, Mann, Alice L, Watt, Stephen, Casale, Francesco Paolo, Sidiropoulos, Nikos, Rapin, Nicolas, Merkel, Angelika, Stunnenberg, Hendrik G, Stegle, Oliver, Frontini, Mattia, Downes, Kate, Pastinen, Tomi, Kuijpers, Taco W, Rico, Daniel, Valencia, Alfonso, Beck, Stephan, Soranzo, Nicole, Paul, Dirk S
Published in Genome Biology (26.01.2017)
Published in Genome Biology (26.01.2017)
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Journal Article
Intestinal organoids as an in vitro platform to characterize disposition, metabolism, and safety profile of small molecules
Kourula, Stephanie, Derksen, Merel, Jardi, Ferran, Jonkers, Sophie, van Heerden, Marjolein, Verboven, Peter, Theuns, Veronique, Van Asten, Stijn, Huybrechts, Tinne, Kunze, Annett, Frazer-Mendelewska, Ewa, Lai, Ka Wai, Overmeer, René, Roos, Jamie Lee, Vries, Robert G.J., Boj, Sylvia F., Monshouwer, Mario, Pourfarzad, Farzin, Snoeys, Jan
Published in European journal of pharmaceutical sciences (01.09.2023)
Published in European journal of pharmaceutical sciences (01.09.2023)
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Journal Article
Organoid-Derived Epithelial Monolayer: A Clinically Relevant In Vitro Model for Intestinal Barrier Function
van Dooremalen, Wies T. M., Derksen, Merel, Roos, Jamie Lee, Higuera Barón, Celia, Verissimo, Carla S., Vries, Robert G. J., Boj, Sylvia F., Pourfarzad, Farzin
Published in Journal of visualized experiments (29.07.2021)
Published in Journal of visualized experiments (29.07.2021)
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