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Gauld, Stephen B, Jacquet, Sebastien, Gauvin, Donna, Wallace, Craig, Wang, Yibing, McCarthy, Richard, Goess, Christian, Leys, Laura, Huang, Susan, Su, Zhi, Edelmayer, Rebecca, Wetter, Joseph, Salte, Katherine, McGaraughty, Steven P, Argiriadi, Maria A, Honore, Prisca, Luccarini, Jean-Michel, Bressac, Didier, Desino, Kelly, Breinlinger, Eric, Cusack, Kevin, Potin, Dominique, Kort, Michael E, Masson, Philippe J
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Published in The Journal of pharmacology and experimental therapeutics (01.10.2019)
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Published in Bioorganic & medicinal chemistry letters (15.07.2019)
Published in Bioorganic & medicinal chemistry letters (15.07.2019)
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Discovery of Selective and Orally Bioavailable Protein Kinase Cθ (PKCθ) Inhibitors from a Fragment Hit
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Published in Journal of medicinal chemistry (08.01.2015)
Published in Journal of medicinal chemistry (08.01.2015)
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Novel 3-(4-piperidinylthio)-1 H -indoles as potent nonopioid orally active central analgesics
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Published in Bioorganic & medicinal chemistry letters (01.04.2000)
Published in Bioorganic & medicinal chemistry letters (01.04.2000)
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Published in The Journal of immunology (1950) (01.04.2010)
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Small Molecule Antagonist of Leukocyte Function Associated Antigen-1 (LFA-1): Structure−Activity Relationships Leading to the Identification of 6-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic Acid (BMS-688521)
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Published in Journal of medicinal chemistry (13.05.2010)
Published in Journal of medicinal chemistry (13.05.2010)
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Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors
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Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
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핵 수용체 조절제
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Year of Publication 08.02.2018
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Year of Publication 08.02.2018
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2-Phenyl-9H-purine-6-carbonitrile derivatives as selective cathepsin S inhibitors
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Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
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Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K: Improving selectivity over hERG
Rankovic, Zoran, Cai, Jiaqiang, Kerr, Jennifer, Fradera, Xavier, Robinson, John, Mistry, Ashvin, Finlay, William, McGarry, George, Andrews, Fiona, Caulfield, Wilson, Cumming, Iain, Dempster, Maureen, Waller, John, Arbuckle, Wullie, Anderson, Mark, Martin, Iain, Mitchell, Ann, Long, Clive, Baugh, Mark, Westwood, Paul, Kinghorn, Emma, Jones, Phil, Uitdehaag, Joost C.M., van Zeeland, Mario, Potin, Dominique, Saniere, Laurent, Fouquet, Andre, Chevallier, François, Deronzier, Hortense, Dorleans, Cecile, Nicolai, Eric
Published in Bioorganic & medicinal chemistry letters (01.11.2010)
Published in Bioorganic & medicinal chemistry letters (01.11.2010)
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Design of LFA-1 antagonists based on a 2,3-dihydro-1H-pyrrolizin-5(7aH)-one scaffold
DODD, Dharmpal S, SHERIFF, Steven, MCKINNON, Murray, BARRISH, Joel C, SUCHARD, Suzanne J, MURALI DHAR, T. G, CHANGE, Chiehying J, STETSKO, Dawn K, PHILLIPS, Linda M, YINGRU ZHANG, LAUNAY, Michele, POTIN, Dominique, VACCARO, Wayne, POSS, Michael A
Published in Bioorganic & medicinal chemistry letters (01.04.2007)
Published in Bioorganic & medicinal chemistry letters (01.04.2007)
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Design of LFA-1 antagonists based on a 2,3-dihydro-1 H-pyrrolizin-5(7aH)-one scaffold
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Published in Bioorganic & medicinal chemistry letters (2007)
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De novo design, synthesis, and in vitro activity of LFA-1 antagonists based on a bicyclic[5.5]hydantoin scaffold
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Published in Bioorganic & medicinal chemistry letters (15.02.2005)
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Year of Publication 26.10.2022
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Year of Publication 14.10.2021
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Year of Publication 06.05.2021
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NUCLEAR RECEPTOR MODULATORS (ROR) FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES
HOBSON, Adrian, BARTH, Martine, BREINLINGER, Eric, POUPARDIN, Olivia, CUSACK, Kevin, AMAUDRUT, Jerôme, MOUNIER, Laurent, ARGIRIADI, Maria, POTIN, Dominique, KORT, Michael
Year of Publication 28.05.2020
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Year of Publication 28.05.2020
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NUCLEAR RECEPTOR MODULATORS (ROR) FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES
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Year of Publication 11.05.2020
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