Single residue in CD28-costimulated CAR-T cells limits long-term persistence and antitumor durability
Guedan, Sonia, Madar, Aviv, Casado-Medrano, Victoria, Shaw, Carolyn, Wing, Anna, Liu, Fang, Young, Regina M, June, Carl H, Posey, Jr, Avery D
Published in The Journal of clinical investigation (01.06.2020)
Published in The Journal of clinical investigation (01.06.2020)
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Advances in cancer immunotherapies
Dagher, Oula K., Schwab, Robert D., Brookens, Shawna K., Posey, Avery D.
Published in Cell (13.04.2023)
Published in Cell (13.04.2023)
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Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma
Posey, Avery D., Schwab, Robert D., Boesteanu, Alina C., Steentoft, Catharina, Mandel, Ulla, Engels, Boris, Stone, Jennifer D., Madsen, Thomas D., Schreiber, Karin, Haines, Kathleen M., Cogdill, Alexandria P., Chen, Taylor J., Song, Decheng, Scholler, John, Kranz, David M., Feldman, Michael D., Young, Regina, Keith, Brian, Schreiber, Hans, Clausen, Henrik, Johnson, Laura A., June, Carl H.
Published in Immunity (Cambridge, Mass.) (21.06.2016)
Published in Immunity (Cambridge, Mass.) (21.06.2016)
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Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies
Parker, Kevin R., Migliorini, Denis, Perkey, Eric, Yost, Kathryn E., Bhaduri, Aparna, Bagga, Puneet, Haris, Mohammad, Wilson, Neil E., Liu, Fang, Gabunia, Khatuna, Scholler, John, Montine, Thomas J., Bhoj, Vijay G., Reddy, Ravinder, Mohan, Suyash, Maillard, Ivan, Kriegstein, Arnold R., June, Carl H., Chang, Howard Y., Posey, Avery D., Satpathy, Ansuman T.
Published in Cell (01.10.2020)
Published in Cell (01.10.2020)
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Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells
Kawalekar, Omkar U., O’Connor, Roddy S., Fraietta, Joseph A., Guo, Lili, McGettigan, Shannon E., Posey, Avery D., Patel, Prachi R., Guedan, Sonia, Scholler, John, Keith, Brian, Snyder, Nathaniel W., Blair, Ian A., Milone, Michael C., June, Carl H.
Published in Immunity (Cambridge, Mass.) (16.02.2016)
Published in Immunity (Cambridge, Mass.) (16.02.2016)
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ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells
Guedan, Sonia, Chen, Xi, Madar, Aviv, Carpenito, Carmine, McGettigan, Shannon E., Frigault, Matthew J., Lee, Jihyun, Posey, Avery D., Scholler, John, Scholler, Nathalie, Bonneau, Richard, June, Carl H.
Published in Blood (14.08.2014)
Published in Blood (14.08.2014)
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Sweet Immune Checkpoint Targets to Enhance T Cell Therapy
Derosiers, Nohelly, Aguilar, William, DeGaramo, David A, Posey, Jr, Avery D
Published in The Journal of immunology (1950) (15.01.2022)
Published in The Journal of immunology (1950) (15.01.2022)
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Driving cars to the clinic for solid tumors
Castellarin, Mauro, Watanabe, Keisuke, June, Carl H., Kloss, Christopher C., Posey, Avery D.
Published in Gene therapy (01.06.2018)
Published in Gene therapy (01.06.2018)
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Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer
Tchou, Julia, Zhao, Yangbing, Levine, Bruce L, Zhang, Paul J, Davis, Megan M, Melenhorst, Jan Joseph, Kulikovskaya, Irina, Brennan, Andrea L, Liu, Xiaojun, Lacey, Simon F, Posey, Jr, Avery D, Williams, Austin D, So, Alycia, Conejo-Garcia, Jose R, Plesa, Gabriela, Young, Regina M, McGettigan, Shannon, Campbell, Jean, Pierce, Robert H, Matro, Jennifer M, DeMichele, Angela M, Clark, Amy S, Cooper, Laurence J, Schuchter, Lynn M, Vonderheide, Robert H, June, Carl H
Published in Cancer immunology research (01.12.2017)
Published in Cancer immunology research (01.12.2017)
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Glycan-directed CAR-T cells
Steentoft, Catharina, Migliorini, Denis, King, Tiffany R, Mandel, Ulla, June, Carl H, Posey, Jr, Avery D
Published in Glycobiology (Oxford) (01.09.2018)
Published in Glycobiology (Oxford) (01.09.2018)
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CAR T-Cell Therapies in Glioblastoma: A First Look
Migliorini, Denis, Dietrich, Pierre-Yves, Stupp, Roger, Linette, Gerald P, Posey, Jr, Avery D, June, Carl H
Published in Clinical cancer research (01.02.2018)
Published in Clinical cancer research (01.02.2018)
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Improving CART-Cell Therapy of Solid Tumors with Oncolytic Virus-Driven Production of a Bispecific T-cell Engager
Wing, Anna, Fajardo, Carlos Alberto, Posey, Jr, Avery D, Shaw, Carolyn, Da, Tong, Young, Regina M, Alemany, Ramon, June, Carl H, Guedan, Sonia
Published in Cancer immunology research (01.05.2018)
Published in Cancer immunology research (01.05.2018)
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Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma
Johnson, Laura A, Scholler, John, Ohkuri, Takayuki, Kosaka, Akemi, Patel, Prachi R, McGettigan, Shannon E, Nace, Arben K, Dentchev, Tzvete, Thekkat, Pramod, Loew, Andreas, Boesteanu, Alina C, Cogdill, Alexandria P, Chen, Taylor, Fraietta, Joseph A, Kloss, Christopher C, Posey, Jr, Avery D, Engels, Boris, Singh, Reshma, Ezell, Tucker, Idamakanti, Neeraja, Ramones, Melissa H, Li, Na, Zhou, Li, Plesa, Gabriela, Seykora, John T, Okada, Hideho, June, Carl H, Brogdon, Jennifer L, Maus, Marcela V
Published in Science translational medicine (18.02.2015)
Published in Science translational medicine (18.02.2015)
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Expression of inducible factors reprograms CAR-T cells for enhanced function and safety
Smole, Anže, Benton, Alexander, Poussin, Mathilde A., Eiva, Monika A., Mezzanotte, Claudia, Camisa, Barbara, Greco, Beatrice, Sharma, Prannda, Minutolo, Nicholas G., Gray, Falon, Bear, Adham S., Baroja, Miren L., Cummins, Casey, Xu, Chong, Sanvito, Francesca, Goldgewicht, Andrea Lang, Blanchard, Tatiana, Rodriguez-Garcia, Alba, Klichinsky, Michael, Bonini, Chiara, June, Carl H., Posey, Avery D., Linette, Gerald P., Carreno, Beatriz M., Casucci, Monica, Powell, Daniel J.
Published in Cancer cell (12.12.2022)
Published in Cancer cell (12.12.2022)
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Combination Therapy for Solid Tumors: Taking a Classic CAR on New Adventures
Dagher, Oula, King, Tiffany R., Wellhausen, Nils, Posey, Avery D.
Published in Cancer cell (09.11.2020)
Published in Cancer cell (09.11.2020)
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