Antihypertensive Effects of an Optimized Aged Garlic Extract in Subjects with Grade I Hypertension and Antihypertensive Drug Therapy: A Randomized, Triple-Blind Controlled Trial
Serrano, José C. E, Castro-Boqué, Eva, García-Carrasco, Alicia, Morán-Valero, María Inés, González-Hedström, Daniel, Bermúdez-López, Marcelino, Valdivielso, José Manuel, Espinel, Alberto E, Portero-Otín, Manuel
Published in Nutrients (23.08.2023)
Published in Nutrients (23.08.2023)
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Oxidative damage compromises energy metabolism in the axonal degeneration mouse model of X-adrenoleukodystrophy
Galino, Jorge, Ruiz, Montserrat, Fourcade, Stéphane, Schlüter, Agatha, López-Erauskin, Jone, Guilera, Cristina, Jove, Mariona, Naudi, Alba, García-Arumí, Elena, Andreu, Antoni L, Starkov, Anatoly A, Pamplona, Reinald, Ferrer, Isidre, Portero-Otin, Manuel, Pujol, Aurora
Published in Antioxidants & redox signaling (15.10.2011)
Published in Antioxidants & redox signaling (15.10.2011)
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Proteins in human brain cortex are modified by oxidation, glycoxidation, and lipoxidation. Effects of Alzheimer disease and identification of lipoxidation targets
Pamplona, Reinald, Dalfó, Esther, Ayala, Victòria, Bellmunt, Maria Josep, Prat, Joan, Ferrer, Isidre, Portero-Otín, Manuel
Published in The Journal of biological chemistry (03.06.2005)
Published in The Journal of biological chemistry (03.06.2005)
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Lipidome analysis in multiple sclerosis reveals protein lipoxidative damage as a potential pathogenic mechanism
Gonzalo, Hugo, Brieva, Luis, Tatzber, Franz, Jové, Mariona, Cacabelos, Daniel, Cassanyé, Anna, Lanau-Angulo, Lucia, Boada, Jordi, Serrano, José C. E., González, Cristina, Hernández, Lourdes, Peralta, Sílvia, Pamplona, Reinald, Portero-Otin, Manuel
Published in Journal of neurochemistry (01.11.2012)
Published in Journal of neurochemistry (01.11.2012)
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Biomarkers of aging in Drosophila
Jacobson, Jake, Lambert, Adrian J., Portero‐Otín, Manuel, Pamplona, Reinald, Magwere, Tapiwanashe, Miwa, Satomi, Driege, Yasmine, Brand, Martin D., Partridge, Linda
Published in Aging cell (01.08.2010)
Published in Aging cell (01.08.2010)
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Colonic Microbiota Profile Characterization of the Responsiveness to Dietary Fibre Treatment in Hypercholesterolemia
Granado-Serrano, Ana Belen, Martín-Garí, Meritxell, Sánchez, Virginia, Riart Solans, Marissa, Lafarga Giribets, Antonia, Berdún, Rebeca, Vilaprinyó, Ester, Portero-Otín, Manuel, Serrano, José C E
Published in Nutrients (25.01.2022)
Published in Nutrients (25.01.2022)
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Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction
Sanz, Alberto, Soikkeli, Mikko, Portero-Otín, Manuel, Wilson, Angela, Kemppainen, Esko, McIlroy, George, Ellilä, Simo, Kemppainen, Kia K, Tuomela, Tea, Lakanmaa, Matti, Kiviranta, Essi, Stefanatos, Rhoda, Dufour, Eric, Hutz, Bettina, Naudí, Alba, Jové, Mariona, Zeb, Akbar, Vartiainen, Suvi, Matsuno-Yagi, Akemi, Yagi, Takao, Rustin, Pierre, Pamplona, Reinald, Jacobs, Howard T
Published in Proceedings of the National Academy of Sciences - PNAS (18.05.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (18.05.2010)
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Aberrant regulation of the GSK ‐3β/ NRF 2 axis unveils a novel therapy for adrenoleukodystrophy
Ranea‐Robles, Pablo, Launay, Nathalie, Ruiz, Montserrat, Calingasan, Noel Ylagan, Dumont, Magali, Naudí, Alba, Portero‐Otín, Manuel, Pamplona, Reinald, Ferrer, Isidre, Beal, M Flint, Fourcade, Stéphane, Pujol, Aurora
Published in EMBO molecular medicine (01.08.2018)
Published in EMBO molecular medicine (01.08.2018)
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Adipocyte lipopolysaccharide binding protein (LBP) is linked to a specific lipidomic signature
Moreno‐Navarrete, José María, Jové, Mariona, Padró, Teresa, Boada, Jordi, Ortega, Francisco, Ricart, Wifredo, Pamplona, Reinald, Badimón, Lina, Portero‐Otín, Manuel, Fernández‐Real, José Manuel
Published in Obesity (Silver Spring, Md.) (01.02.2017)
Published in Obesity (Silver Spring, Md.) (01.02.2017)
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Targeted activation of CREB in reactive astrocytes is neuroprotective in focal acute cortical injury
Pardo, Luis, Schlüter, Agatha, Valor, Luis M., Barco, Angel, Giralt, Mercedes, Golbano, Arantxa, Hidalgo, Juan, Jia, Peilin, Zhao, Zhongming, Jové, Mariona, Portero-Otin, Manuel, Ruiz, Montserrat, Giménez-Llort, Lydia, Masgrau, Roser, Pujol, Aurora, Galea, Elena
Published in Glia (01.05.2016)
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TSHB mRNA is linked to cholesterol metabolism in adipose tissue
Moreno-Navarrete, José María, Moreno, María, Ortega, Francisco, Xifra, Gemma, Hong, Shangyu, Asara, John M, Serrano, José C E, Jové, Mariona, Pissios, Pavlos, Blüher, Matthias, Ricart, Wifredo, Portero-Otin, Manuel, Fernández-Real, José Manuel
Published in The FASEB journal (01.10.2017)
Published in The FASEB journal (01.10.2017)
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Selective brain regional changes in lipid profile with human aging
Mota-Martorell, Natalia, Andrés-Benito, Pol, Martín-Gari, Meritxell, Galo-Licona, José Daniel, Sol, Joaquim, Fernández-Bernal, Anna, Portero-Otín, Manuel, Ferrer, Isidro, Jove, Mariona, Pamplona, Reinald
Published in GeroScience (01.04.2022)
Published in GeroScience (01.04.2022)
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A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling
Echtay, Karim S., Esteves, Telma C., Pakay, Julian L., Jekabsons, Mika B., Lambert, Adrian J., Portero-Otín, Manuel, Pamplona, Reinald, Vidal-Puig, Antonio J., Wang, Steven, Roebuck, Stephen J., Brand, Martin D.
Published in The EMBO journal (15.08.2003)
Published in The EMBO journal (15.08.2003)
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Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-β: implications for diabetic atherosclerosis
Cantero, Anne-Valerie, Portero-Otín, Manuel, Ayala, Victòria, Auge, Nathalie, Sanson, Marie, Elbaz, Meyer, Thiers, Jean-Claude, Pamplona, Reinald, Salvayre, Robert, Nègre-Salvayre, Anne
Published in The FASEB journal (01.10.2007)
Published in The FASEB journal (01.10.2007)
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Adipose Tissue Protein Glycoxidation is Associated with Weight‐Loss Potential
Serrano, José C. E., Baena‐Fustegueras, Juan Antonio, Martin‐Gari, Meritxell, Rassendren, Helene, Cassanye, Anna, Naudí, Alba, López‐Cano, Carolina, Sánchez, Enric, de la Fuente‐Juárez, María Cruz, Herrerías González, Fernando, Olsina Kissler, Jorge J., Lecube, Albert, Portero‐Otín, Manuel
Published in Obesity (Silver Spring, Md.) (01.07.2019)
Published in Obesity (Silver Spring, Md.) (01.07.2019)
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Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis
Cacabelos, Daniel, Ayala, Victòria, Granado-Serrano, Ana Belén, Jové, Mariona, Torres, Pascual, Boada, Jordi, Cabré, Rosanna, Ramírez-Núñez, Omar, Gonzalo, Hugo, Soler-Cantero, Aranzazu, Serrano, José Carlos Enrique, Bellmunt, Maria Josep, Romero, María Paz, Motilva, María José, Nonaka, Takashi, Hasegawa, Masato, Ferrer, Isidre, Pamplona, Reinald, Portero-Otín, Manuel
Published in Neurobiology of disease (01.04.2016)
Published in Neurobiology of disease (01.04.2016)
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Specific Metabolomics Adaptations Define a Differential Regional Vulnerability in the Adult Human Cerebral Cortex
Cabré, Rosanna, Jové, Mariona, Naudí, Alba, Ayala, Victoria, Piñol-Ripoll, Gerard, Gil-Villar, Maria P, Dominguez-Gonzalez, Mayelin, Obis, Èlia, Berdun, Rebeca, Mota-Martorell, Natalia, Portero-Otin, Manuel, Ferrer, Isidre, Pamplona, Reinald
Published in Frontiers in molecular neuroscience (08.12.2016)
Published in Frontiers in molecular neuroscience (08.12.2016)
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High-Fat Diet-Induced Obesity Increases Brain Mitochondrial Complex I and Lipoxidation-Derived Protein Damage
Berdún, Rebeca, Obis, Èlia, Mota-Martorell, Natàlia, Bassols, Anna, Valent, Daniel, Serrano, José C E, Martín-Garí, Meritxell, Rodríguez-Palmero, María, Moreno-Muñoz, José Antonio, Tibau, Joan, Quintanilla, Raquel, Pamplona, Reinald, Portero-Otín, Manuel, Jové, Mariona
Published in Antioxidants (01.01.2024)
Published in Antioxidants (01.01.2024)
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Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease
Pamplona, Reinald, Naudí, Alba, Gavín, Rosalina, Pastrana, Miguel A., Sajnani, Gustavo, Ilieva, Ekaterina V., del Río, José Antonio, Portero-Otín, Manuel, Ferrer, Isidre, Requena, Jesús R.
Published in Free radical biology & medicine (15.10.2008)
Published in Free radical biology & medicine (15.10.2008)
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