Structure, mechanism, and inhibition of the zinc-dependent histone deacetylases
Porter, Nicholas J, Christianson, David W
Published in Current opinion in structural biology (01.12.2019)
Published in Current opinion in structural biology (01.12.2019)
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Journal Article
Biocatalytic Carbene Transfer Using Diazirines
Porter, Nicholas J., Danelius, Emma, Gonen, Tamir, Arnold, Frances H.
Published in Journal of the American Chemical Society (25.05.2022)
Published in Journal of the American Chemical Society (25.05.2022)
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Journal Article
Histone deacetylase 10 structure and molecular function as a polyamine deacetylase
Hai, Yang, Shinsky, Stephen A., Porter, Nicholas J., Christianson, David W.
Published in Nature communications (18.05.2017)
Published in Nature communications (18.05.2017)
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Journal Article
Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors
Vögerl, Katharina, Ong, Nghia, Senger, Johanna, Herp, Daniel, Schmidtkunz, Karin, Marek, Martin, Müller, Martin, Bartel, Karin, Shaik, Tajith B, Porter, Nicholas J, Robaa, Dina, Christianson, David W, Romier, Christophe, Sippl, Wolfgang, Jung, Manfred, Bracher, Franz
Published in Journal of medicinal chemistry (14.02.2019)
Published in Journal of medicinal chemistry (14.02.2019)
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Journal Article
MicroED Structure of a Protoglobin Reactive Carbene Intermediate
Danelius, Emma, Porter, Nicholas J., Unge, Johan, Arnold, Frances H., Gonen, Tamir
Published in Journal of the American Chemical Society (05.04.2023)
Published in Journal of the American Chemical Society (05.04.2023)
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Journal Article
Entropy as a Driver of Selectivity for Inhibitor Binding to Histone Deacetylase 6
Porter, Nicholas J, Wagner, Florence F, Christianson, David W
Published in Biochemistry (Easton) (03.07.2018)
Published in Biochemistry (Easton) (03.07.2018)
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Journal Article
Histone Deacetylase 6‑Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity
Porter, Nicholas J, Osko, Jeremy D, Diedrich, Daniela, Kurz, Thomas, Hooker, Jacob M, Hansen, Finn K, Christianson, David W
Published in Journal of medicinal chemistry (13.09.2018)
Published in Journal of medicinal chemistry (13.09.2018)
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Journal Article
Iron Heme Enzyme-Catalyzed Cyclopropanations with Diazirines as Carbene Precursors: Computational Explorations of Diazirine Activation and Cyclopropanation Mechanism
Rogge, Torben, Zhou, Qingyang, Porter, Nicholas J., Arnold, Frances H., Houk, K. N.
Published in Journal of the American Chemical Society (07.02.2024)
Published in Journal of the American Chemical Society (07.02.2024)
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Journal Article
Laser wavelength metrology with low-finesse etalons and Bayer filters
Nicholas Porter, J, Jackson, Jarom S, Durfee, Dallin S, Sandberg, Richard L
Published in Optics express (07.12.2020)
Published in Optics express (07.12.2020)
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Journal Article
Structural aspects of HDAC8 mechanism and dysfunction in Cornelia de Lange syndrome spectrum disorders
Deardorff, Matthew A., Porter, Nicholas J., Christianson, David W.
Published in Protein science (01.11.2016)
Published in Protein science (01.11.2016)
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Journal Article
A combinatorially complete epistatic fitness landscape in an enzyme active site
Johnston, Kadina E, Almhjell, Patrick J, Watkins-Dulaney, Ella J, Liu, Grace, Porter, Nicholas J, Yang, Jason, Arnold, Frances H
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2024)
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Journal Article
Structural analysis of histone deacetylase 8 mutants associated with Cornelia de Lange Syndrome spectrum disorders
Osko, Jeremy D., Porter, Nicholas J., Decroos, Christophe, Lee, Matthew S., Watson, Paris R., Raible, Sarah E., Krantz, Ian D., Deardorff, Matthew A., Christianson, David W.
Published in Journal of structural biology (01.03.2021)
Published in Journal of structural biology (01.03.2021)
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Journal Article
Exploring Structural Determinants of Inhibitor Affinity and Selectivity in Complexes with Histone Deacetylase 6
Osko, Jeremy D, Porter, Nicholas J, Narayana Reddy, Poli Adi, Xiao, You-Cai, Rokka, Johanna, Jung, Manfred, Hooker, Jacob M, Salvino, Joseph M, Christianson, David W
Published in Journal of medicinal chemistry (09.01.2020)
Published in Journal of medicinal chemistry (09.01.2020)
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Journal Article
Mapping nanocrystal orientations via scanning Laue diffraction microscopy for multi‐peak Bragg coherent diffraction imaging
Zhang, Yueheng, Porter, J. Nicholas, Wilkin, Matthew J., Harder, Ross, Cha, Wonsuk, Suter, Robert M., Liu, He, Schnebly, Landon, Sandberg, Richard L., Miller, Joshua A., Tischler, Jon, Pateras, Anastasios, Rollett, Anthony D.
Published in Journal of synchrotron radiation (01.07.2023)
Published in Journal of synchrotron radiation (01.07.2023)
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