Comparison of algorithms for the detection of cancer drivers at subgene resolution
Porta-Pardo, Eduard, Kamburov, Atanas, Tamborero, David, Pons, Tirso, Grases, Daniela, Valencia, Alfonso, Lopez-Bigas, Nuria, Getz, Gad, Godzik, Adam
Published in Nature methods (01.08.2017)
Published in Nature methods (01.08.2017)
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Role of POLE and POLD1 in familial cancer
Mur, Pilar, García-Mulero, Sandra, del Valle, Jesús, Magraner-Pardo, Lorena, Vidal, August, Pineda, Marta, Cinnirella, Giacomo, Martín-Ramos, Edgar, Pons, Tirso, López-Doriga, Adriana, Belhadj, Sami, Feliubadaló, Lidia, Munoz-Torres, Pau M., Navarro, Matilde, Grau, Elia, Darder, Esther, Llort, Gemma, Sanz, Judit, Ramón y Cajal, Teresa, Balmana, Judith, Brunet, Joan, Moreno, Victor, Piulats, Josep M., Matías-Guiu, Xavier, Sanz-Pamplona, Rebeca, Aligué, Rosa, Capellá, Gabriel, Lázaro, Conxi, Valle, Laura
Published in Genetics in medicine (01.12.2020)
Published in Genetics in medicine (01.12.2020)
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Towards a detailed atlas of protein–protein interactions
Mosca, Roberto, Pons, Tirso, Céol, Arnaud, Valencia, Alfonso, Aloy, Patrick
Published in Current opinion in structural biology (01.12.2013)
Published in Current opinion in structural biology (01.12.2013)
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Impaired stem cell differentiation and somatic cell reprogramming in DIDO3 mutants with altered RNA processing and increased R-loop levels
Fütterer, Agnes, Talavera-Gutiérrez, Amaia, Pons, Tirso, de Celis, Jesús, Gutiérrez, Julio, Domínguez Plaza, Verónica, Martínez-A, Carlos
Published in Cell death & disease (21.06.2021)
Published in Cell death & disease (21.06.2021)
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Systematic Analysis of FASTK Gene Family Alterations in Cancer
Magraner-Pardo, Lorena, Gobelli, Dino, de la Fuente, Miguel A, Pons, Tirso, Simarro, María
Published in International journal of molecular sciences (20.10.2021)
Published in International journal of molecular sciences (20.10.2021)
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Journal Article
KSR induces RAS‐independent MAPK pathway activation and modulates the efficacy of KRAS inhibitors
Paniagua, Guillem, Jacob, Harrys K.C., Brehey, Oksana, García‐Alonso, Sara, Lechuga, Carmen G., Pons, Tirso, Musteanu, Monica, Guerra, Carmen, Drosten, Matthias, Barbacid, Mariano
Published in Molecular oncology (01.09.2022)
Published in Molecular oncology (01.09.2022)
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Solving the enigma of POLD1 p.V295M as a potential cause of increased cancer risk
Mur, Pilar, Magraner-Pardo, Lorena, García-Mulero, Sandra, Díez-Villanueva, Anna, Del Valle, Jesús, Ezquerro, Elsa, Lázaro, Conxi, Capellá, Gabriel, Moreno, Victor, Sanz-Pamplona, Rebeca, Pons, Tirso, Valle, Laura
Published in European journal of human genetics : EJHG (01.04.2022)
Published in European journal of human genetics : EJHG (01.04.2022)
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Recommendations for the classification of germline variants in the exonuclease domain of POLE and POLD1
Mur, Pilar, Viana-Errasti, Julen, García-Mulero, Sandra, Magraner-Pardo, Lorena, Muéoz, Inés G, Pons, Tirso, Capellá, Gabriel, Pineda, Marta, Feliubadaló, Lidia, Valle, Laura
Published in Genome medicine (17.10.2023)
Published in Genome medicine (17.10.2023)
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Poorly Conserved P15 Proteins of Cileviruses Retain Elements of Common Ancestry and Putative Functionality: A Theoretical Assessment on the Evolution of Cilevirus Genomes
Ramos-González, Pedro L., Pons, Tirso, Chabi-Jesus, Camila, Arena, Gabriella Dias, Freitas-Astua, Juliana
Published in Frontiers in plant science (05.11.2021)
Published in Frontiers in plant science (05.11.2021)
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Exome Sequencing of Plasma DNA Portrays the Mutation Landscape of Colorectal Cancer and Discovers Mutated VEGFR2 Receptors as Modulators of Antiangiogenic Therapies
Toledo, Rodrigo A, Garralda, Elena, Mitsi, Maria, Pons, Tirso, Monsech, Jorge, Vega, Estela, Otero, Álvaro, Albarran, Maria I, Baños, Natalia, Durán, Yolanda, Bonilla, Victoria, Sarno, Francesca, Camacho-Artacho, Marta, Sanchez-Perez, Tania, Perea, Sofia, Álvarez, Rafael, De Martino, Alba, Lietha, Daniel, Blanco-Aparicio, Carmen, Cubillo, Antonio, Domínguez, Orlando, Martínez-Torrecuadrada, Jorge L, Hidalgo, Manuel
Published in Clinical cancer research (01.08.2018)
Published in Clinical cancer research (01.08.2018)
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Elucidating the molecular basis of MSH2-deficient tumors by combined germline and somatic analysis
Vargas-Parra, Gardenia M, González-Acosta, Maribel, Thompson, Bryony A, Gómez, Carolina, Fernández, Anna, Dámaso, Estela, Pons, Tirso, Morak, Monika, Del Valle, Jesús, Iglesias, Silvia, Velasco, Àngela, Solanes, Ares, Sanjuan, Xavier, Padilla, Natàlia, de la Cruz, Xavier, Valencia, Alfonso, Holinski-Feder, Elke, Brunet, Joan, Feliubadaló, Lídia, Lázaro, Conxi, Navarro, Matilde, Pineda, Marta, Capellá, Gabriel
Published in International journal of cancer (01.10.2017)
Published in International journal of cancer (01.10.2017)
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Journal Article
Lack of evidence for germline WWP1 pathogenic variants in gastrointestinal polyposis and other phenotypes suggestive of PTEN-hamartoma-tumor syndrome
Gonzalez-Abuin, Noemi, Pons, Tirso, Fuster, Teresa, Quintana, Isabel, Terradas, Mariona, Aiza, Gemma, Brunet, Joan, Capellá, Gabriel, Hampel, Heather, Valle, Laura
Published in Genes & diseases (01.03.2024)
Published in Genes & diseases (01.03.2024)
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Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis
Mur, Pilar, De Voer, Richarda M, Olivera-Salguero, Rubén, Rodríguez-Perales, Sandra, Pons, Tirso, Setién, Fernando, Aiza, Gemma, Valdés-Mas, Rafael, Bertini, Angelo, Pineda, Marta, Vreede, Lilian, Navarro, Matilde, Iglesias, Silvia, González, Sara, Brunet, Joan, Valencia, Alfonso, Esteller, Manel, Lázaro, Conxi, Kops, Geert J P L, Urioste, Miguel, Puente, Xose S, Capellá, Gabriel, Valle, Laura
Published in Molecular cancer (15.02.2018)
Published in Molecular cancer (15.02.2018)
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The Kunitz-Type Protein ShPI-1 Inhibits Serine Proteases and Voltage-Gated Potassium Channels
García-Fernández, Rossana, Peigneur, Steve, Pons, Tirso, Alvarez, Carlos, González, Lidice, Chávez, María A, Tytgat, Jan
Published in Toxins (13.04.2016)
Published in Toxins (13.04.2016)
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Somatic Embryonic FGFR2 Mutations in Keratinocytic Epidermal Nevi
Toll, Agustí, Fernández, Luis C., Pons, Tirso, Groesser, Leopold, Sagrera, Ana, Carrillo-de Santa Pau, Enrique, Vicente, Asunción, Baselga, Eulàlia, Vázquez, Miguel, Beltrán, Sergi, Pisano, David G., Rueda, Daniel, Gut, Marta, Pujol, Ramon M., Hafner, Christian, Gut, Ivo, Valencia, Alfonso, Real, Francisco X.
Published in Journal of investigative dermatology (01.08.2016)
Published in Journal of investigative dermatology (01.08.2016)
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Geleophysic dysplasia: novel missense variants and insights into ADAMTSL2 intracellular trafficking
Piccolo, Pasquale, Sabatino, Valeria, Mithbaokar, Pratibha, Polishchuck, Elena, Law, Simon K., Magraner-Pardo, Lorena, Pons, Tirso, Polishchuck, Roman, Brunetti-Pierri, Nicola
Published in Molecular genetics and metabolism reports (01.12.2019)
Published in Molecular genetics and metabolism reports (01.12.2019)
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Journal Article
Crystal structure of levansucrase from the Gram-negative bacterium Gluconacetobacter diazotrophicus
Martínez-Fleites, Carlos, Ortíz-Lombardía, Miguel, Pons, Tirso, Tarbouriech, Nicolas, Taylor, Edward J, Arrieta, Juan G, Hernández, Lázaro, Davies, Gideon J
Published in Biochemical journal (15.08.2005)
Published in Biochemical journal (15.08.2005)
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PhcrTx2, a New Crab-Paralyzing Peptide Toxin from the Sea Anemone Phymanthus crucifer
Rodríguez, Armando Alexei, Garateix, Anoland, Salceda, Emilio, Peigneur, Steve, Zaharenko, André Junqueira, Pons, Tirso, Santos, Yúlica, Arreguín, Roberto, Ständker, Ludger, Forssmann, Wolf-Georg, Tytgat, Jan, Vega, Rosario, Soto, Enrique
Published in Toxins (07.02.2018)
Published in Toxins (07.02.2018)
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