The long history of iron in the Universe and in health and disease
Sheftel, Alex D., Mason, Anne B., Ponka, Prem
Published in Biochimica et biophysica acta (01.03.2012)
Published in Biochimica et biophysica acta (01.03.2012)
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Journal Article
Transferrin receptor 1 controls systemic iron homeostasis by fine-tuning hepcidin expression to hepatocellular iron load
Fillebeen, Carine, Charlebois, Edouard, Wagner, John, Katsarou, Angeliki, Mui, Jeannie, Vali, Hojatollah, Garcia-Santos, Daniel, Ponka, Prem, Presley, John, Pantopoulos, Kostas
Published in Blood (24.01.2019)
Published in Blood (24.01.2019)
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Journal Article
A Class of Iron Chelators with a Wide Spectrum of Potent Antitumor Activity That Overcomes Resistance to Chemotherapeutics
Whitnall, Megan, Howard, Jonathan, Ponka, Prem, Richardson, Des R.
Published in Proceedings of the National Academy of Sciences - PNAS (03.10.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (03.10.2006)
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Journal Article
Erythroid cell mitochondria receive endosomal iron by a “kiss-and-run” mechanism
Hamdi, Amel, Roshan, Tariq M., Kahawita, Tanya M., Mason, Anne B., Sheftel, Alex D., Ponka, Prem
Published in Biochimica et biophysica acta (01.12.2016)
Published in Biochimica et biophysica acta (01.12.2016)
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Journal Article
Do Mammalian Cells Really Need to Export and Import Heme?
Ponka, Prem, Sheftel, Alex D., English, Ann M., Scott Bohle, D., Garcia-Santos, Daniel
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.05.2017)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.05.2017)
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Journal Article
Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol
Richardson, Des R., Lane, Darius J. R., Becker, Frika M., Huang, Michael L.-H., Whitnall, Megan, Rahmanto, Yohan Suryo, Sheftel, Alex D., Ponka, Prem, Snyder, Solomon H.
Published in Proceedings of the National Academy of Sciences - PNAS (15.06.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (15.06.2010)
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Journal Article
Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant
Huang, Michael Li-Hsuan, Becker, Erika M, Whitnall, Megan, Rahmanto, Yohan Suryo, Ponka, Prem, Richardson, Des R
Published in Proceedings of the National Academy of Sciences - PNAS (22.09.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (22.09.2009)
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Journal Article
Direct interorganellar transfer of iron from endosome to mitochondrion
Sheftel, Alex D., Zhang, An-Sheng, Brown, Claire, Shirihai, Orian S., Ponka, Prem
Published in Blood (01.07.2007)
Published in Blood (01.07.2007)
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Journal Article
Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells
Garcia-Santos, Daniel, Schranzhofer, Matthias, Bergeron, Richard, Sheftel, Alex D, Ponka, Prem
Published in Haematologica (Roma) (01.08.2017)
Published in Haematologica (Roma) (01.08.2017)
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Journal Article
Dysregulation of Iron Homeostasis in the CNS Contributes to Disease Progression in a Mouse Model of Amyotrophic Lateral Sclerosis
Jeong, Suh Young, Rathore, Khizr I, Schulz, Katrin, Ponka, Prem, Arosio, Paolo, David, Samuel
Published in The Journal of neuroscience (21.01.2009)
Published in The Journal of neuroscience (21.01.2009)
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Journal Article
Nramp1 promotes efficient macrophage recycling of iron following erythrophagocytosis in vivo
Soe-Lin, Shan, Apte, Sameer S, Andriopoulos, Billy Jr, Andrews, Marc C, Schranzhofer, Matthias, Kahawita, Tanya, Garcia-Santos, Daniel, Ponka, Prem
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (07.04.2009)
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Journal Article
Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia
Whitnall, Megan, Rahmanto, Yohan Suryo, Huang, Michael L.-H, Saletta, Federica, Lok, Hiu Chuen, Gutiérrez, Lucía, Lázaro, Francisco J, Fleming, Adam J, St. Pierre, Tim G, Mikhael, Marc R, Ponka, Prem, Richardson, Des R
Published in Proceedings of the National Academy of Sciences - PNAS (11.12.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (11.12.2012)
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Journal Article
Lysosomal proteolysis is the primary degradation pathway for cytosolic ferritin and cytosolic ferritin degradation is necessary for iron exit
Zhang, Yinghui, Mikhael, Marc, Xu, Dongxue, Li, Yiye, Soe-Lin, Shan, Ning, Bo, Li, Wei, Nie, Guangjun, Zhao, Yuliang, Ponka, Prem
Published in Antioxidants & redox signaling (01.10.2010)
Published in Antioxidants & redox signaling (01.10.2010)
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Journal Article
The transferrin receptor: role in health and disease
Ponka, Prem, Lok, Chun Nam
Published in International Journal of Biochemistry and Cell Biology (01.10.1999)
Published in International Journal of Biochemistry and Cell Biology (01.10.1999)
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Book Review
Journal Article
Snx3 Regulates Recycling of the Transferrin Receptor and Iron Assimilation
Chen, Caiyong, Garcia-Santos, Daniel, Ishikawa, Yuichi, Seguin, Alexandra, Li, Liangtao, Fegan, Katherine H., Hildick-Smith, Gordon J., Shah, Dhvanit I., Cooney, Jeffrey D., Chen, Wen, King, Matthew J., Yien, Yvette Y., Schultz, Iman J., Anderson, Heidi, Dalton, Arthur J., Freedman, Matthew L., Kingsley, Paul D., Palis, James, Hattangadi, Shilpa M., Lodish, Harvey F., Ward, Diane M., Kaplan, Jerry, Maeda, Takahiro, Ponka, Prem, Paw, Barry H.
Published in Cell metabolism (05.03.2013)
Published in Cell metabolism (05.03.2013)
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Journal Article
The mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria
Laroque, Aurélie, Min-Oo, Gundula, Tam, Mifong, Ponka, Prem, Stevenson, Mary M, Gros, Philippe
Published in PloS one (18.05.2017)
Published in PloS one (18.05.2017)
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Journal Article