Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasis
Adair, Brian D., Alonso, José L., van Agthoven, Johannes, Hayes, Vincent, Ahn, Hyun Sook, Yu, I-Shing, Lin, Shu-Wha, Xiong, Jian-Ping, Poncz, Mortimer, Arnaout, M. Amin
Published in Nature communications (21.01.2020)
Published in Nature communications (21.01.2020)
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Journal Article
The C-terminal CGHC motif of protein disulfide isomerase supports thrombosis
Zhou, Junsong, Wu, Yi, Wang, Lu, Rauova, Lubica, Hayes, Vincent M, Poncz, Mortimer, Essex, David W
Published in The Journal of clinical investigation (01.12.2015)
Published in The Journal of clinical investigation (01.12.2015)
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Journal Article
Atomic description of the immune complex involved in heparin-induced thrombocytopenia
Cai, Zheng, Yarovoi, Serge V., Zhu, Zhiqiang, Rauova, Lubica, Hayes, Vincent, Lebedeva, Tatiana, Liu, Qun, Poncz, Mortimer, Arepally, Gowthami, Cines, Douglas B., Greene, Mark I.
Published in Nature communications (22.09.2015)
Published in Nature communications (22.09.2015)
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Journal Article
Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia
Tutwiler, Valerie, Madeeva, Daria, Ahn, Hyun Sook, Andrianova, Izabella, Hayes, Vincent, Zheng, X. Long, Cines, Douglas B., McKenzie, Steven E., Poncz, Mortimer, Rauova, Lubica
Published in Blood (28.01.2016)
Published in Blood (28.01.2016)
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Journal Article
Induced Pluripotent Stem Cell-Derived Megakaryocytes and Platelets for Disease Modeling and Future Clinical Applications
Borst, Sara, Sim, Xiuli, Poncz, Mortimer, French, Deborah L, Gadue, Paul
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2017)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2017)
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Journal Article
Serpin functions in host-pathogen interactions
Bao, Jialing, Pan, Guoqing, Poncz, Mortimer, Wei, Junhong, Ran, Maoshuang, Zhou, Zeyang
Published in PeerJ (San Francisco, CA) (05.04.2018)
Published in PeerJ (San Francisco, CA) (05.04.2018)
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Journal Article
The disulfide isomerase ERp72 supports arterial thrombosis in mice
Zhou, Junsong, Wu, Yi, Chen, Fengwu, Wang, Lu, Rauova, Lubica, Hayes, Vincent M., Poncz, Mortimer, Li, Hong, Liu, Tong, Liu, Junling, Essex, David W.
Published in Blood (10.08.2017)
Published in Blood (10.08.2017)
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Journal Article
Challenges and promises for the development of donor-independent platelet transfusions
Lambert, Michele P., Sullivan, Spencer K., Fuentes, Rudy, French, Deborah L., Poncz, Mortimer
Published in Blood (25.04.2013)
Published in Blood (25.04.2013)
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Journal Article
Complement mediates binding and procoagulant effects of ultralarge HIT immune complexes
Khandelwal, Sanjay, Barnes, Ayiesha, Rauova, Lubica, Sarkar, Amrita, Rux, Ann H., Yarovoi, Serge V., Zaitsev, S. Sergei, Lambris, John D., Myoung, Sooho S., Johnson, Alexandra, Lee, Grace M., Duarte, Madelaine, Poncz, Mortimer, Arepally, Gowthami M., Cines, Douglas B.
Published in Blood (25.11.2021)
Published in Blood (25.11.2021)
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Journal Article
Platelet-Specific Chemokines Contribute to the Pathogenesis of Acute Lung Injury
Bdeir, Khalil, Gollomp, Kandace, Stasiak, Marta, Mei, Junjie, Papiewska-Pajak, Izabela, Zhao, Guohua, Worthen, G Scott, Cines, Douglas B, Poncz, Mortimer, Kowalska, M Anna
Published in American journal of respiratory cell and molecular biology (01.02.2017)
Published in American journal of respiratory cell and molecular biology (01.02.2017)
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Journal Article
Neutrophils promote clearance of nuclear debris following acid-induced lung injury
Oved, Joseph H., Paris, Andrew J., Gollomp, Kandace, Dai, Ning, Rubey, Kathryn, Wang, Ping, Spruce, Lynn A., Seeholzer, Steven H., Poncz, Mortimer, Worthen, G. Scott
Published in Blood (21.01.2021)
Published in Blood (21.01.2021)
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Journal Article
Platelet integrin αIIbβ3 plays a key role in a venous thrombogenesis mouse model
Adair, Brian D., Field, Conroy O., Alonso, José L., Xiong, Jian-Ping, Deng, Shi-Xian, Ahn, Hyun Sook, Mashin, Eivgeni, Clish, Clary B., van Agthoven, Johannes, Yeager, Mark, Guo, Youzhong, Tess, David A., Landry, Donald W., Poncz, Mortimer, Arnaout, M. Amin
Published in Nature communications (04.10.2024)
Published in Nature communications (04.10.2024)
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Journal Article
Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway
Khandelwal, Sanjay, Ravi, Joann, Rauova, Lubica, Johnson, Alexandra, Lee, Grace M., Gilner, Jennifer B., Gunti, Sreenivasulu, Notkins, Abner L., Kuchibhatla, Maragatha, Frank, Michael, Poncz, Mortimer, Cines, Douglas B., Arepally, Gowthami M.
Published in Blood (06.12.2018)
Published in Blood (06.12.2018)
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Journal Article
Comparative analysis of human ex vivo–generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale
Wang, Yuhuan, Hayes, Vincent, Jarocha, Danuta, Sim, Xiuli, Harper, Dawn C., Fuentes, Rudy, Sullivan, Spencer K., Gadue, Paul, Chou, Stella T., Torok-Storb, Beverly J., Marks, Michael S., French, Deborah L., Poncz, Mortimer
Published in Blood (04.06.2015)
Published in Blood (04.06.2015)
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Journal Article
Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf
Ono, Yukako, Wang, Yuhuan, Suzuki, Hidenori, Okamoto, Shinichiro, Ikeda, Yasuo, Murata, Mitsuru, Poncz, Mortimer, Matsubara, Yumiko
Published in Blood (01.11.2012)
Published in Blood (01.11.2012)
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Journal Article
CRISPR/Cas9-mediated conversion of human platelet alloantigen allotypes
Zhang, Nanyan, Zhi, Huiying, Curtis, Brian R., Rao, Sridhar, Jobaliya, Chintan, Poncz, Mortimer, French, Deborah L., Newman, Peter J.
Published in Blood (11.02.2016)
Published in Blood (11.02.2016)
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Journal Article
Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo
Zhi, Huiying, Rauova, Lubica, Hayes, Vincent, Gao, Cunji, Boylan, Brian, Newman, Debra K., McKenzie, Steven E., Cooley, Brian C., Poncz, Mortimer, Newman, Peter J.
Published in Blood (07.03.2013)
Published in Blood (07.03.2013)
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Journal Article