All-Assay-Max2 pQSAR: Activity Predictions as Accurate as Four-Concentration IC50s for 8558 Novartis Assays
Martin, Eric J, Polyakov, Valery R, Zhu, Xiang-Wei, Tian, Li, Mukherjee, Prasenjit, Liu, Xin
Published in Journal of chemical information and modeling (28.10.2019)
Published in Journal of chemical information and modeling (28.10.2019)
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Building Machine Learning Small Molecule Melting Points and Solubility Models Using CCDC Melting Points Dataset
Zhu, Xiangwei, Polyakov, Valery R., Bajjuri, Krishna, Hu, Huiyong, Maderna, Andreas, Tovee, Clare A., Ward, Suzanna C.
Published in Journal of chemical information and modeling (22.05.2023)
Published in Journal of chemical information and modeling (22.05.2023)
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Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF
Shao, Wenlin, Mishina, Yuji M, Feng, Yun, Caponigro, Giordano, Cooke, Vesselina G, Rivera, Stacy, Wang, Yingyun, Shen, Fang, Korn, Joshua M, Mathews Griner, Lesley A, Nishiguchi, Gisele, Rico, Alice, Tellew, John, Haling, Jacob R, Aversa, Robert, Polyakov, Valery, Zang, Richard, Hekmat-Nejad, Mohammad, Amiri, Payman, Singh, Mallika, Keen, Nicholas, Dillon, Michael P, Lees, Emma, Ramurthy, Savithri, Sellers, William R, Stuart, Darrin D
Published in Cancer research (Chicago, Ill.) (15.03.2018)
Published in Cancer research (Chicago, Ill.) (15.03.2018)
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All-Assay-Max2 pQSAR: Activity Predictions as Accurate as Four-Concentration IC 50 s for 8558 Novartis Assays
Martin, Eric J, Polyakov, Valery R, Zhu, Xiang-Wei, Tian, Li, Mukherjee, Prasenjit, Liu, Xin
Published in Journal of chemical information and modeling (28.10.2019)
Published in Journal of chemical information and modeling (28.10.2019)
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X‐ray Structures and Feasibility Assessment of CLK2 Inhibitors for Phelan–McDermid Syndrome
Kallen, Joerg, Bergsdorf, Christian, Arnaud, Bertrand, Bernhard, Mario, Brichet, Murielle, Cobos‐Correa, Amanda, Elhajouji, Azeddine, Freuler, Felix, Galimberti, Ivan, Guibourdenche, Christel, Haenni, Simon, Holzinger, Sandra, Hunziker, Juerg, Izaac, Aude, Kaufmann, Markus, Leder, Lukas, Martus, Hans‐Joerg, von Matt, Peter, Polyakov, Valery, Roethlisberger, Patrik, Roma, Guglielmo, Stiefl, Nikolaus, Uteng, Marianne, Lerchner, Andreas
Published in ChemMedChem (19.09.2018)
Published in ChemMedChem (19.09.2018)
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Enrichment Analysis for Discovering Biological Associations in Phenotypic Screens
Polyakov, Valery R, Moorcroft, Neil D, Drawid, Amar
Published in Journal of chemical information and modeling (24.02.2014)
Published in Journal of chemical information and modeling (24.02.2014)
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Over 14-year survival of pressed e.max lithium disilicate glass-ceramic complete and partial coverage restorations in patients with severe wear: A prospective clinical study
Margvelashvili-Malament, Mariam, Thompson, Van, Polyakov, Valery, Malament, Kenneth A.
Published in The Journal of prosthetic dentistry (30.07.2024)
Published in The Journal of prosthetic dentistry (30.07.2024)
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Decision support systems in drug discovery
Shen, Jian, Polyakov, Valery, Rachapudi, Ramesh, You, Tony
Published in Mini reviews in medicinal chemistry (01.12.2004)
Published in Mini reviews in medicinal chemistry (01.12.2004)
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Synthesis, characterization, and molecular structure of a gallium(III) complex of an amine-phenol ligand with activity against chloroquine-sensitive Plasmodium falciparum strains
Ocheskey, Joseph A., Polyakov, Valery R., Harpstrite, Scott E., Oksman, Anna, Goldberg, Daniel E., Piwnica-Worms, David, Sharma, Vijay
Published in Journal of inorganic biochemistry (15.01.2003)
Published in Journal of inorganic biochemistry (15.01.2003)
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Incidence of endodontic therapy after complete or partial coverage glass-ceramic restorations with a follow-up time of over 30 years: A prospective clinical study
Malament, Kenneth A., Margvelashvili-Malament, Mariam, Natto, Zuhair S., Polyakov, Valery, Thompson, Van, Rekow, Dianne
Published in The Journal of prosthetic dentistry (01.01.2023)
Published in The Journal of prosthetic dentistry (01.01.2023)
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Design and Discovery of N‑(3-(2-(2-Hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide, a Selective, Efficacious, and Well-Tolerated RAF Inhibitor Targeting RAS Mutant Cancers: The Path to the Clinic
Ramurthy, Savithri, Taft, Benjamin R, Aversa, Robert J, Barsanti, Paul A, Burger, Matthew T, Lou, Yan, Nishiguchi, Gisele A, Rico, Alice, Setti, Lina, Smith, Aaron, Subramanian, Sharadha, Tamez, Victoriano, Tanner, Huw, Wan, Lifeng, Hu, Cheng, Appleton, Brent A, Mamo, Mulugeta, Tandeske, Laura, Tellew, John E, Huang, Shenlin, Yue, Qin, Chaudhary, Apurva, Tian, Hung, Iyer, Raman, Hassan, A. Quamrul, Mathews Griner, Lesley A, La Bonte, Laura R, Cooke, Vesselina G, Van Abbema, Anne, Merritt, Hanne, Gampa, Kalyani, Feng, Fei, Yuan, Jing, Mishina, Yuji, Wang, Yingyun, Haling, Jacob R, Vaziri, Sepideh, Hekmat-Nejad, Mohammad, Polyakov, Valery, Zang, Richard, Sethuraman, Vijay, Amiri, Payman, Singh, Mallika, Sellers, William R, Lees, Emma, Shao, Wenlin, Dillon, Michael P, Stuart, Darrin D
Published in Journal of medicinal chemistry (12.03.2020)
Published in Journal of medicinal chemistry (12.03.2020)
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Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative Bacteria
Moreau, Robert J, Skepper, Colin K, Appleton, Brent A, Blechschmidt, Anke, Balibar, Carl J, Benton, Bret M, Drumm, Joseph E, Feng, Brian Y, Geng, Mei, Li, Cindy, Lindvall, Mika K, Lingel, Andreas, Lu, Yipin, Mamo, Mulugeta, Mergo, Wosenu, Polyakov, Valery, Smith, Thomas M, Takeoka, Kenneth, Uehara, Kyoko, Wang, Lisha, Wei, Jun-Rong, Weiss, Andrew H, Xie, Lili, Xu, Wenjian, Zhang, Qiong, de Vicente, Javier
Published in Journal of medicinal chemistry (26.04.2018)
Published in Journal of medicinal chemistry (26.04.2018)
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Design and Discovery of N‑(2-Methyl-5′-morpholino-6′-((tetrahydro‑2H‑pyran-4-yl)oxy)-[3,3′-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers
Nishiguchi, Gisele A, Rico, Alice, Tanner, Huw, Aversa, Robert J, Taft, Benjamin R, Subramanian, Sharadha, Setti, Lina, Burger, Matthew T, Wan, Lifeng, Tamez, Victoriano, Smith, Aaron, Lou, Yan, Barsanti, Paul A, Appleton, Brent A, Mamo, Mulugeta, Tandeske, Laura, Dix, Ina, Tellew, John E, Huang, Shenlin, Mathews Griner, Lesley A, Cooke, Vesselina G, Van Abbema, Anne, Merritt, Hanne, Ma, Sylvia, Gampa, Kalyani, Feng, Fei, Yuan, Jing, Wang, Yingyun, Haling, Jacob R, Vaziri, Sepideh, Hekmat-Nejad, Mohammad, Jansen, Johanna M, Polyakov, Valery, Zang, Richard, Sethuraman, Vijay, Amiri, Payman, Singh, Mallika, Lees, Emma, Shao, Wenlin, Stuart, Darrin D, Dillon, Michael P, Ramurthy, Savithri
Published in Journal of medicinal chemistry (22.06.2017)
Published in Journal of medicinal chemistry (22.06.2017)
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