Molecular Classification of the PORTEC-3 Trial for High-Risk Endometrial Cancer: Impact on Prognosis and Benefit From Adjuvant Therapy
León-Castillo, Alicia, de Boer, Stephanie M, Powell, Melanie E, Mileshkin, Linda R, Mackay, Helen J, Leary, Alexandra, Nijman, Hans W, Singh, Naveena, Pollock, Pamela M, Bessette, Paul, Fyles, Anthony, Haie-Meder, Christine, Smit, Vincent T H B M, Edmondson, Richard J, Putter, Hein, Kitchener, Henry C, Crosbie, Emma J, de Bruyn, Marco, Nout, Remi A, Horeweg, Nanda, Creutzberg, Carien L, Bosse, Tjalling
Published in Journal of clinical oncology (10.10.2020)
Published in Journal of clinical oncology (10.10.2020)
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Immunological profiling of molecularly classified high-risk endometrial cancers identifies POLE-mutant and microsatellite unstable carcinomas as candidates for checkpoint inhibition
Eggink, Florine A., Van Gool, Inge C., Leary, Alexandra, Pollock, Pamela M., Crosbie, Emma J., Mileshkin, Linda, Jordanova, Ekaterina S., Adam, Julien, Freeman-Mills, Luke, Church, David N., Creutzberg, Carien L., De Bruyn, Marco, Nijman, Hans W., Bosse, Tjalling
Published in Oncoimmunology (01.02.2017)
Published in Oncoimmunology (01.02.2017)
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FGFR2 point mutations in 466 endometrioid endometrial tumors: relationship with MSI, KRAS, PIK3CA, CTNNB1 mutations and clinicopathological features
Byron, Sara A, Gartside, Michael, Powell, Matthew A, Wellens, Candice L, Gao, Feng, Mutch, David G, Goodfellow, Paul J, Pollock, Pamela M
Published in PloS one (23.02.2012)
Published in PloS one (23.02.2012)
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The N550K/H Mutations in FGFR2 Confer Differential Resistance to PD173074, Dovitinib, and Ponatinib ATP-Competitive Inhibitors
Byron, Sara A, Chen, Huaibin, Wortmann, Andreas, Loch, David, Gartside, Michael G, Dehkhoda, Farhad, Blais, Steven P, Neubert, Thomas A, Mohammadi, Moosa, Pollock, Pamela M
Published in Neoplasia (New York, N.Y.) (01.08.2013)
Published in Neoplasia (New York, N.Y.) (01.08.2013)
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Patient-derived xenograft models capture genomic heterogeneity in endometrial cancer
Bonazzi, Vanessa F, Kondrashova, Olga, Smith, Deborah, Nones, Katia, Sengal, Asmerom T, Ju, Robert, Packer, Leisl M, Koufariotis, Lambros T, Kazakoff, Stephen H, Davidson, Aimee L, Ramarao-Milne, Priya, Lakis, Vanessa, Newell, Felicity, Rogers, Rebecca, Davies, Claire, Nicklin, James, Garrett, Andrea, Chetty, Naven, Perrin, Lewis, Pearson, John V, Patch, Ann-Marie, Waddell, Nicola, Pollock, Pamela M
Published in Genome medicine (10.01.2022)
Published in Genome medicine (10.01.2022)
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Refining prognosis and identifying targetable pathways for high-risk endometrial cancer; a TransPORTEC initiative
Stelloo, Ellen, Bosse, Tjalling, Nout, Remi A, MacKay, Helen J, Church, David N, Nijman, Hans W, Leary, Alexandra, Edmondson, Richard J, Powell, Melanie E, Crosbie, Emma J, Kitchener, Henry C, Mileshkin, Linda, Pollock, Pamela M, Smit, Vincent T, Creutzberg, Carien L
Published in Modern pathology (01.06.2015)
Published in Modern pathology (01.06.2015)
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Inhibition of Activated Fibroblast Growth Factor Receptor 2 in Endometrial Cancer Cells Induces Cell Death Despite PTEN Abrogation
BYRON, Sara A, GARTSIDE, Michael G, WELLENS, Candice L, MALLON, Mary A, KEENAN, Jack B, POWELL, Matthew A, GOODFELLOW, Paul J, POLLOCK, Pamela M
Published in Cancer research (Chicago, Ill.) (01.09.2008)
Published in Cancer research (Chicago, Ill.) (01.09.2008)
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Bcl‐2 inhibitors enhance FGFR inhibitor‐induced mitochondrial‐dependent cell death in FGFR2‐mutant endometrial cancer
Packer, Leisl M., Stehbens, Samantha J., Bonazzi, Vanessa F., Gunter, Jennifer H., Ju, Robert J., Ward, Micheal, Gartside, Michael G., Byron, Sara A., Pollock, Pamela M.
Published in Molecular oncology (01.04.2019)
Published in Molecular oncology (01.04.2019)
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Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells
QIN, Jian-Zhong, ZIFFRA, Jeffrey, RIZZO, Paola, MIELE, Lucio, NICKOLOFF, Brian J, STENNETT, Lawrence, BODNER, Barbara, BONISH, Brian K, CHATURVEDI, Vijaya, BENNETT, Frank, POLLOCK, Pamela M, TRENT, Jeffrey M, HENDRIX, Mary J. C
Published in Cancer research (Chicago, Ill.) (15.07.2005)
Published in Cancer research (Chicago, Ill.) (15.07.2005)
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Endometrial cancer PDX-derived organoids (PDXOs) and PDXs with FGFR2c isoform expression are sensitive to FGFR inhibition
Sengal, Asmerom T., Bonazzi, Vanessa, Smith, Deborah, Moiola, Cristian P., Lourie, Rohan, Rogers, Rebecca, Colas, Eva, Gil-Moreno, Antonio, Frentzas, Sophia, Chetty, Naven, Perrin, Lewis, Pollock, Pamela M.
Published in NPJ precision oncology (08.12.2023)
Published in NPJ precision oncology (08.12.2023)
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A Common Variant at the 14q32 Endometrial Cancer Risk Locus Activates AKT1 through YY1 Binding
Painter, Jodie N., Kaufmann, Susanne, O’Mara, Tracy A., Hillman, Kristine M., Sivakumaran, Haran, Darabi, Hatef, Cheng, Timothy H.T., Pearson, John, Kazakoff, Stephen, Waddell, Nicola, Hoivik, Erling A., Goode, Ellen L., Scott, Rodney J., Tomlinson, Ian, Dunning, Alison M., Easton, Douglas F., French, Juliet D., Salvesen, Helga B., Pollock, Pamela M., Thompson, Deborah J., Spurdle, Amanda B., Edwards, Stacey L.
Published in American journal of human genetics (02.06.2016)
Published in American journal of human genetics (02.06.2016)
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The Prognostic and Predictive Value of Melanoma-related MicroRNAs Using Tissue and Serum: A MicroRNA Expression Analysis
Stark, Mitchell S., Klein, Kerenaftali, Weide, Benjamin, Haydu, Lauren E., Pflugfelder, Annette, Tang, Yue Hang, Palmer, Jane M., Whiteman, David C., Scolyer, Richard A., Mann, Graham J., Thompson, John F., Long, Georgina V., Barbour, Andrew P., Soyer, H. Peter, Garbe, Claus, Herington, Adrian, Pollock, Pamela M., Hayward, Nicholas K.
Published in EBioMedicine (01.07.2015)
Published in EBioMedicine (01.07.2015)
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Active Notch1 Confers a Transformed Phenotype to Primary Human Melanocytes
PINNIX, Chelsea C, LEE, John T, YASHIRO-OHTANI, Yumi, NATHANSON, Katherine L, BENGSTON, Ana, POLLOCK, Pamela M, WEERARATNA, Ashani T, NICKOLOFF, Brian J, PEAR, Warren S, CAPOBIANCO, Anthony J, HERLYN, Meenhard, LIU, Zhao-Jun, MCDAID, Ronan, BALINT, Klara, BEVERLY, Levi J, BRAFFORD, Patricia A, MIN XIAO, HIMES, Benjamin, ZABIEROWSKI, Susan E
Published in Cancer research (Chicago, Ill.) (01.07.2009)
Published in Cancer research (Chicago, Ill.) (01.07.2009)
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Spatial expression of the FGFR2b splice isoform and its prognostic significance in endometrioid endometrial carcinoma
Sengal, Asmerom T, Smith, Deborah, Snell, Cameron E, Leung, Samuel, Talhouk, Aline, Williams, Elizabeth D, McAlpine, Jessica N, Pollock, Pamela M
Published in The journal of pathology. Clinical research (01.11.2022)
Published in The journal of pathology. Clinical research (01.11.2022)
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Loss-of-Function Fibroblast Growth Factor Receptor-2 Mutations in Melanoma
Gartside, Michael G, Chen, Huaibin, Ibrahimi, Omar A, Byron, Sara A, Curtis, Amy V, Wellens, Candice L, Bengston, Ana, Yudt, Laura M, Eliseenkova, Anna V, Ma, Jinghong, Curtin, John A, Hyder, Pilar, Harper, Ursula L, Riedesel, Erica, Mann, Graham J, Trent, Jeffrey M, Bastian, Boris C, Meltzer, Paul S, Mohammadi, Moosa, Pollock, Pamela M
Published in Molecular cancer research (01.01.2009)
Published in Molecular cancer research (01.01.2009)
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Cellular Settings Mediating Src Substrate Switching between Focal Adhesion Kinase Tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) Tyrosine 734
Wortmann, Andreas, He, Yaowu, Christensen, Melinda E., Linn, MayLa, Lumley, John W., Pollock, Pamela M., Waterhouse, Nigel J., Hooper, John D.
Published in The Journal of biological chemistry (09.12.2011)
Published in The Journal of biological chemistry (09.12.2011)
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A genome-based strategy uncovers frequent BRAF mutations in melanoma
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Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN status
Byron, Sara A, Loch, David C, Wellens, Candice L, Wortmann, Andreas, Wu, Jiayi, Wang, John, Nomoto, Kenichi, Pollock, Pamela M
Published in Molecular cancer (05.10.2012)
Published in Molecular cancer (05.10.2012)
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crystallographic snapshot of tyrosine trans-phosphorylation in action
Chen, Huaibin, Xu, Chong-Feng, Ma, Jinghong, Eliseenkova, Anna V, Li, Wanqing, Pollock, Pamela M, Pitteloud, Nelly, Miller, W. Todd, Neubert, Thomas A, Mohammadi, Moosa
Published in Proceedings of the National Academy of Sciences - PNAS (16.12.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (16.12.2008)
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