Search Results - "POIROT Laurent" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Multiplex Genome-Edited T-cell Manufacturing Platform for "Off-the-Shelf" Adoptive T-cell Immunotherapies

Multiplex Genome-Edited T-cell Manufacturing Platform for "Off-the-Shelf" Adoptive T-cell Immunotherapies

by Poirot, Laurent, Philip, Brian, Schiffer-Mannioui, Cécile, Le Clerre, Diane, Chion-Sotinel, Isabelle, Derniame, Sophie, Potrel, Pierrick, Bas, Cécile, Lemaire, Laetitia, Galetto, Roman, Lebuhotel, Céline, Eyquem, Justin, Cheung, Gordon Weng-Kit, Duclert, Aymeric, Gouble, Agnès, Arnould, Sylvain, Peggs, Karl, Pule, Martin, Scharenberg, Andrew M, Smith, Julianne
Published in Cancer research (Chicago, Ill.) (15.09.2015)

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Stromal depletion by TALEN-edited universal hypoimmunogenic FAP-CAR T cells enables infiltration and anti-tumor cytotoxicity of tumor antigen-targeted CAR-T immunotherapy

Stromal depletion by TALEN-edited universal hypoimmunogenic FAP-CAR T cells enables infiltration and anti-tumor cytotoxicity of tumor antigen-targeted CAR-T immunotherapy

by Das, Shipra, Valton, Julien, Duchateau, Philippe, Poirot, Laurent
Published in Frontiers in immunology (12.05.2023)

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Endowing universal CAR T-cell with immune-evasive properties using TALEN-gene editing

Endowing universal CAR T-cell with immune-evasive properties using TALEN-gene editing

by Jo, Sumin, Das, Shipra, Williams, Alan, Chretien, Anne-Sophie, Pagliardini, Thomas, Le Roy, Aude, Fernandez, Jorge Postigo, Le Clerre, Diane, Jahangiri, Billal, Chion-Sotinel, Isabelle, Rozlan, Sandra, Dessez, Emilie, Gouble, Agnes, Dusséaux, Mathilde, Galetto, Roman, Duclert, Aymeric, Marcenaro, Emanuela, Devillier, Raynier, Olive, Daniel, Duchateau, Philippe, Poirot, Laurent, Valton, Julien
Published in Nature communications (30.06.2022)

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Modulation of chimeric antigen receptor surface expression by a small molecule switch

Modulation of chimeric antigen receptor surface expression by a small molecule switch

by Juillerat, Alexandre, Tkach, Diane, Busser, Brian W, Temburni, Sonal, Valton, Julien, Duclert, Aymeric, Poirot, Laurent, Depil, Stéphane, Duchateau, Philippe
Published in BMC biotechnology (03.07.2019)

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Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy

Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy

by Silva, George, Poirot, Laurent, Galetto, Roman, Smith, Julianne, Montoya, Guillermo, Duchateau, Philippe, Pâques, Frédéric
Published in Current gene therapy (01.02.2011)

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Repurposing endogenous immune pathways to tailor and control chimeric antigen receptor T cell functionality

Repurposing endogenous immune pathways to tailor and control chimeric antigen receptor T cell functionality

by Sachdeva, Mohit, Busser, Brian W., Temburni, Sonal, Jahangiri, Billal, Gautron, Anne-Sophie, Maréchal, Alan, Juillerat, Alexandre, Williams, Alan, Depil, Stéphane, Duchateau, Philippe, Poirot, Laurent, Valton, Julien
Published in Nature communications (13.11.2019)

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Gene editing of PKLR gene in human hematopoietic progenitors through 5' and 3' UTR modified TALEN mRNA

Gene editing of PKLR gene in human hematopoietic progenitors through 5' and 3' UTR modified TALEN mRNA

by Quintana-Bustamante, Oscar, Fañanas-Baquero, Sara, Orman, Israel, Torres, Raul, Duchateau, Philippe, Poirot, Laurent, Gouble, Agnès, Bueren, Juan A, Segovia, Jose C
Published in PloS one (16.10.2019)

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Optimized two‐step electroporation process to achieve efficient nonviral‐mediated gene insertion into primary T cells

Optimized two‐step electroporation process to achieve efficient nonviral‐mediated gene insertion into primary T cells

by Yang, Ming, Tkach, Diane, Boyne, Alex, Kazancioglu, Selena, Duclert, Aymeric, Poirot, Laurent, Duchateau, Philippe, Juillerat, Alexandre
Published in FEBS open bio (01.01.2022)

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254 TGF-beta blockade combined with activation-induced IL12 secretion synergize to optimize potency of MUC1-CAR T-cells in preclinical targeting of triple-negative breast cancer

254 TGF-beta blockade combined with activation-induced IL12 secretion synergize to optimize potency of MUC1-CAR T-cells in preclinical targeting of triple-negative breast cancer

by Erler, Piril, Cho, Hana, Skinner, Jordan, Poirot, Laurent, Aranda-Orgilles, Beatriz
Published in Journal for immunotherapy of cancer (01.11.2023)

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The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain

The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain

by Beisner, Daniel R, Langerak, Petra, Parker, Albert E, Dahlberg, Carol, Otero, Francella J, Sutton, Sue E, Poirot, Laurent, Barnes, Whitney, Young, Michael A, Niessen, Sherry, Wiltshire, Tim, Bodendorf, Ursula, Martoglio, Bruno, Cravatt, Benjamin, Cooke, Michael P
Published in The Journal of experimental medicine (14.01.2013)

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Natural Killer Cells Distinguish Innocuous and Destructive Forms of Pancreatic Islet Autoimmunity

Natural Killer Cells Distinguish Innocuous and Destructive Forms of Pancreatic Islet Autoimmunity

by Poirot, Laurent, Benoist, Christophe, Mathis, Diane
Published in Proceedings of the National Academy of Sciences - PNAS (25.05.2004)

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Author Correction: Repurposing endogenous immune pathways to tailor and control chimeric antigen receptor T cell functionality

Author Correction: Repurposing endogenous immune pathways to tailor and control chimeric antigen receptor T cell functionality

by Sachdeva, Mohit, Busser, Brian W., Temburni, Sonal, Jahangiri, Billal, Gautron, Anne-Sophie, Maréchal, Alan, Juillerat, Alexandre, Williams, Alan, Depil, Stéphane, Duchateau, Philippe, Poirot, Laurent, Valton, Julien
Published in Nature communications (07.05.2020)

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Straightforward Generation of Ultrapure Off-the-Shelf Allogeneic CAR-T Cells

Straightforward Generation of Ultrapure Off-the-Shelf Allogeneic CAR-T Cells

by Juillerat, Alexandre, Tkach, Diane, Yang, Ming, Boyne, Alex, Valton, Julien, Poirot, Laurent, Duchateau, Philippe
Published in Frontiers in bioengineering and biotechnology (25.06.2020)

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Fine and Predictable Tuning of TALEN Gene Editing Targeting for Improved T Cell Adoptive Immunotherapy

Fine and Predictable Tuning of TALEN Gene Editing Targeting for Improved T Cell Adoptive Immunotherapy

by Gautron, Anne-Sophie, Juillerat, Alexandre, Guyot, Valérie, Filhol, Jean-Marie, Dessez, Emilie, Duclert, Aymeric, Duchateau, Philippe, Poirot, Laurent
Published in Molecular therapy. Nucleic acids (15.12.2017)

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Optimized tuning of TALEN specificity using non-conventional RVDs

Optimized tuning of TALEN specificity using non-conventional RVDs

by Juillerat, Alexandre, Pessereau, Coline, Dubois, Gwendoline, Guyot, Valérie, Maréchal, Alan, Valton, Julien, Daboussi, Fayza, Poirot, Laurent, Duclert, Aymeric, Duchateau, Philippe
Published in Scientific reports (30.01.2015)

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Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases

Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases

by Daboussi, Fayza, Zaslavskiy, Mikhail, Poirot, Laurent, Loperfido, Mariana, Gouble, Agnès, Guyot, Valerie, Leduc, Sophie, Galetto, Roman, Grizot, Sylvestre, Oficjalska, Danusia, Perez, Christophe, Delacôte, Fabien, Dupuy, Aurélie, Chion-Sotinel, Isabelle, Le Clerre, Diane, Lebuhotel, Céline, Danos, Olivier, Lemaire, Frédéric, Oussedik, Kahina, Cédrone, Frédéric, Epinat, Jean-Charles, Smith, Julianne, Yáñez-Muñoz, Rafael J, Dickson, George, Popplewell, Linda, Koo, Taeyoung, VandenDriessche, Thierry, Chuah, Marinee K, Duclert, Aymeric, Duchateau, Philippe, Pâques, Frédéric
Published in Nucleic acids research (01.07.2012)

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Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells

Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells

by Garate, Zita, Quintana-Bustamante, Oscar, Crane, Ana M., Olivier, Emmanuel, Poirot, Laurent, Galetto, Roman, Kosinski, Penelope, Hill, Collin, Kung, Charles, Agirre, Xabi, Orman, Israel, Cerrato, Laura, Alberquilla, Omaira, Rodriguez-Fornes, Fatima, Fusaki, Noemi, Garcia-Sanchez, Felix, Maia, Tabita M., Ribeiro, Maria L., Sevilla, Julian, Prosper, Felipe, Jin, Shengfang, Mountford, Joanne, Guenechea, Guillermo, Gouble, Agnes, Bueren, Juan A., Davis, Brian R., Segovia, Jose C.
Published in Stem cell reports (08.12.2015)

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Pre-TCRα supports CD3-dependent reactivation and expansion of TCRα-deficient primary human T-cells

Pre-TCRα supports CD3-dependent reactivation and expansion of TCRα-deficient primary human T-cells

by Galetto, Román, Lebuhotel, Celine, Poirot, Laurent, Gouble, Agnès, Toribio, Maria L, Smith, Julianne, Scharenberg, Andrew
Published in Molecular therapy. Methods & clinical development (01.01.2014)

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Granulocyte–macrophage colony-stimulating factor inactivation in CAR T-cells prevents monocyte-dependent release of key cytokine release syndrome mediators

Granulocyte–macrophage colony-stimulating factor inactivation in CAR T-cells prevents monocyte-dependent release of key cytokine release syndrome mediators

by Sachdeva, Mohit, Duchateau, Philippe, Depil, Stéphane, Poirot, Laurent, Valton, Julien
Published in The Journal of biological chemistry (05.04.2019)

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An oxygen sensitive self-decision making engineered CAR T-cell

An oxygen sensitive self-decision making engineered CAR T-cell

by Juillerat, Alexandre, Marechal, Alan, Filhol, Jean Marie, Valogne, Yannick, Valton, Julien, Duclert, Aymeric, Duchateau, Philippe, Poirot, Laurent
Published in Scientific reports (20.01.2017)

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