Gene Inactivation of Proprotein Convertase Subtilisin/Kexin Type 9 Reduces Atherosclerosis in Mice
DENIS, Maxime, MARCINKIEWICZ, Jadwiga, ZAID, Ahmed, GAUTHIER, Dany, POIRIER, Steve, LAZURE, Claude, SEIDAH, Nabil G, PRAT, Annik
Published in Circulation (New York, N.Y.) (21.02.2012)
Published in Circulation (New York, N.Y.) (21.02.2012)
Get full text
Journal Article
Trafficking Dynamics of PCSK9-Induced LDLR Degradation: Focus on Human PCSK9 Mutations and C-Terminal Domain
Poirier, Steve, Hamouda, Hocine Ait, Villeneuve, Louis, Demers, Annie, Mayer, Gaétan
Published in PloS one (09.06.2016)
Published in PloS one (09.06.2016)
Get full text
Journal Article
The Proprotein Convertase PCSK9 Induces the Degradation of Low Density Lipoprotein Receptor (LDLR) and Its Closest Family Members VLDLR and ApoER2
Poirier, Steve, Mayer, Gaetan, Benjannet, Suzanne, Bergeron, Eric, Marcinkiewicz, Jadwiga, Nassoury, Nasha, Mayer, Harald, Nimpf, Johannes, Prat, Annik, Seidah, Nabil G.
Published in The Journal of biological chemistry (25.01.2008)
Published in The Journal of biological chemistry (25.01.2008)
Get full text
Journal Article
GRP94 Regulates Circulating Cholesterol Levels through Blockade of PCSK9-Induced LDLR Degradation
Poirier, Steve, Mamarbachi, Maya, Chen, Wan-Ting, Lee, Amy S., Mayer, Gaetan
Published in Cell reports (Cambridge) (15.12.2015)
Published in Cell reports (Cambridge) (15.12.2015)
Get full text
Journal Article
Annexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradation
Seidah, Nabil G, Poirier, Steve, Denis, Maxime, Parker, Rex, Miao, Bowman, Mapelli, Claudio, Prat, Annik, Wassef, Hanny, Davignon, Jean, Hajjar, Katherine A, Mayer, Gaétan
Published in PloS one (27.07.2012)
Published in PloS one (27.07.2012)
Get full text
Journal Article
The anti-hypercholesterolemic effect of low p53 expression protects vascular endothelial function in mice
Leblond, Francois, Poirier, Steve, Yu, Carol, Duquette, Natacha, Mayer, Gaetan, Thorin, Eric
Published in PloS one (19.03.2014)
Published in PloS one (19.03.2014)
Get full text
Journal Article
Implication of the proprotein convertase NARC‐1/PCSK9 in the development of the nervous system
Poirier, Steve, Prat, Annik, Marcinkiewicz, Edwige, Paquin, Joanne, Chitramuthu, Babykumari P., Baranowski, David, Cadieux, Benoit, Bennett, Hugh P. J., Seidah, Nabil G.
Published in Journal of neurochemistry (01.08.2006)
Published in Journal of neurochemistry (01.08.2006)
Get full text
Journal Article
Dissection of the Endogenous Cellular Pathways of PCSK9-induced Low Density Lipoprotein Receptor Degradation
Poirier, Steve, Mayer, Gaetan, Poupon, Viviane, McPherson, Peter S., Desjardins, Roxane, Ly, Kevin, Asselin, Marie-Claude, Day, Robert, Duclos, Franck J., Witmer, Mark, Parker, Rex, Prat, Annik, Seidah, Nabil G.
Published in The Journal of biological chemistry (16.10.2009)
Published in The Journal of biological chemistry (16.10.2009)
Get full text
Journal Article
Dissection of the endogenous cellular pathways of PCSK9-induced low density lipoprotein receptor degradation: evidence for an intracellular route
Poirier, Steve, Mayer, Gaetan, Poupon, Viviane, McPherson, Peter S, Desjardins, Roxane, Ly, Kevin, Asselin, Marie-Claude, Day, Robert, Duclos, Franck J, Witmer, Mark, Parker, Rex, Prat, Annik, Seidah, Nabil G
Published in The Journal of biological chemistry (16.10.2009)
Published in The Journal of biological chemistry (16.10.2009)
Get full text
Journal Article
The activation and physiological functions of the proprotein convertases
Seidah, Nabil G., Mayer, Gaetan, Zaid, Ahmed, Rousselet, Estelle, Nassoury, Nasha, Poirier, Steve, Essalmani, Rachid, Prat, Annik
Published in The international journal of biochemistry & cell biology (01.01.2008)
Published in The international journal of biochemistry & cell biology (01.01.2008)
Get full text
Journal Article
Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other
Butkinaree, Chutikarn, Canuel, Maryssa, Essalmani, Rachid, Poirier, Steve, Benjannet, Suzanne, Asselin, Marie-Claude, Roubtsova, Anna, Hamelin, Josée, Marcinkiewicz, Jadwiga, Chamberland, Ann, Guillemot, Johann, Mayer, Gaétan, Sisodia, Sangram S., Jacob, Yves, Prat, Annik, Seidah, Nabil G.
Published in The Journal of biological chemistry (24.07.2015)
Published in The Journal of biological chemistry (24.07.2015)
Get full text
Journal Article
The Epigenetic Drug 5-Azacytidine Interferes with Cholesterol and Lipid Metabolism
Poirier, Steve, Samami, Samaneh, Mamarbachi, Maya, Demers, Annie, Chang, Ta Yuan, Vance, Dennis E., Hatch, Grant M., Mayer, Gaétan
Published in The Journal of biological chemistry (04.07.2014)
Published in The Journal of biological chemistry (04.07.2014)
Get full text
Journal Article
The Cytosolic Adaptor AP‐1A Is Essential for the Trafficking and Function of Niemann‐Pick Type C Proteins
Poirier, Steve, Mayer, Gaétan, Murphy, Stephanie R., Garver, William S., Chang, Ta Yuan, Schu, Peter, Seidah, Nabil G.
Published in Traffic (Copenhagen, Denmark) (01.04.2013)
Published in Traffic (Copenhagen, Denmark) (01.04.2013)
Get full text
Journal Article
The Anti-Hypercholesterolemic Effect of Low p53 Expression Protects Vascular Endothelial Function in Mice: e92394
Leblond, Francois, Poirier, Steve, Yu, Carol, Duquette, Natacha, Mayer, Gaetan, Thorin, Eric
Published in PloS one (01.03.2014)
Published in PloS one (01.03.2014)
Get full text
Journal Article