Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2
Tummino, Tia A, Rezelj, Veronica V, Fischer, Benoit, Fischer, Audrey, O'Meara, Matthew J, Monel, Blandine, Vallet, Thomas, White, Kris M, Zhang, Ziyang, Alon, Assaf, Schadt, Heiko, O'Donnell, Henry R, Lyu, Jiankun, Rosales, Romel, McGovern, Briana L, Rathnasinghe, Raveen, Jangra, Sonia, Schotsaert, Michael, Galarneau, Jean-René, Krogan, Nevan J, Urban, Laszlo, Shokat, Kevan M, Kruse, Andrew C, García-Sastre, Adolfo, Schwartz, Olivier, Moretti, Francesca, Vignuzzi, Marco, Pognan, Francois, Shoichet, Brian K
Published in Science (30.07.2021)
Published in Science (30.07.2021)
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The eTOX data-sharing project to advance in silico drug-induced toxicity prediction
Cases, Montserrat, Briggs, Katharine, Steger-Hartmann, Thomas, Pognan, François, Marc, Philippe, Kleinöder, Thomas, Schwab, Christof H, Pastor, Manuel, Wichard, Jörg, Sanz, Ferran
Published in International journal of molecular sciences (14.11.2014)
Published in International journal of molecular sciences (14.11.2014)
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The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives
Pognan, François, Steger-Hartmann, Thomas, Díaz, Carlos, Blomberg, Niklas, Bringezu, Frank, Briggs, Katharine, Callegaro, Giulia, Capella-Gutierrez, Salvador, Centeno, Emilio, Corvi, Javier, Drew, Philip, Drewe, William C, Fernández, José M, Furlong, Laura I, Guney, Emre, Kors, Jan A, Mayer, Miguel Angel, Pastor, Manuel, Piñero, Janet, Ramírez-Anguita, Juan Manuel, Ronzano, Francesco, Rowell, Philip, Saüch-Pitarch, Josep, Valencia, Alfonso, van de Water, Bob, van der Lei, Johan, van Mulligen, Erik, Sanz, Ferran
Published in Pharmaceuticals (Basel, Switzerland) (08.03.2021)
Published in Pharmaceuticals (Basel, Switzerland) (08.03.2021)
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eTRANSAFE: data science to empower translational safety assessment
Sanz, Ferran, Pognan, François, Steger-Hartmann, Thomas, Díaz, Carlos, Asakura, Shoji, Amberg, Alexander, Bécourt-Lhote, Nathalie, Blomberg, Niklas, Bosc, Nicolas, Briggs, Katharine, Bringezu, Frank, Brulle-Wohlhueter, Claire, Brunak, Søren, Bueters, Ruud, Callegaro, Giulia, Capella-Gutierrez, Salvador, Centeno, Emilio, Corvi, Javier, Cronin, Mark T. D., Drew, Philip, Duchateau-Nguyen, Guillemette, Ecker, Gerhard F., Escher, Sylvia, Felix, Eloy, Ferreiro, Miguel, Frericks, Markus, Furlong, Laura I., Geiger, Robert, George, Catherine, Grandits, Melanie, Ivanov-Draganov, Dragomir, Kilgour-Christie, Jean, Kiziloren, Tevfik, Kors, Jan A., Koyama, Naoki, Kreuchwig, Annika, Leach, Andrew R., Mayer, Miguel-Angel, Monecke, Peter, Muster, Wolfgang, Nakazawa, Chihiro Miyamoto, Nicholson, Gavin, Parry, Rowan, Pastor, Manuel, Piñero, Janet, Oberhauser, Nils, Ramírez-Anguita, Juan Manuel, Rodrigo, Adrián, Smajic, Aljosa, Schaefer, Markus, Schieferdecker, Sebastian, Soininen, Inari, Terricabras, Emma, Trairatphisan, Panuwat, Turner, Sean C., Valencia, Alfonso, van de Water, Bob, van der Lei, Johan L., van Mulligen, Erik M., Vock, Esther, Wilkinson, David
Published in Nature reviews. Drug discovery (01.08.2023)
Published in Nature reviews. Drug discovery (01.08.2023)
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Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology
Tonge, Robert, Shaw, Joanne, Middleton, Brian, Rowlinson, Rachel, Rayner, Steve, Young, Janice, Pognan, Francois, Hawkins, Edward, Currie, Ian, Davison, Matthew
Published in Proteomics (Weinheim) (01.03.2001)
Published in Proteomics (Weinheim) (01.03.2001)
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Synthesis and Structure-Activity Relationship of Methyl-Substituted Indolo[2,3-b]quinolines: Novel Cytotoxic, DNA Topoisomerase II Inhibitors
Peczynska-Czoch, Wanda, Pognan, Francois, Kaczmarek, Lukasz, Boratynski, Janusz
Published in Journal of medicinal chemistry (01.10.1994)
Published in Journal of medicinal chemistry (01.10.1994)
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Bile Acid Sequestration by Cholestyramine Mitigates FGFR4 Inhibition-Induced ALT Elevation
Schadt, Heiko S, Wolf, Armin, Mahl, Joerg Andreas, Wuersch, Kuno, Couttet, Philippe, Schwald, Marianne, Fischer, Audrey, Lienard, Mathilde, Emotte, Corinne, Teng, Chi-Hse, Skuba, Elizabeth, Richardson, Terrilyn A, Manenti, Luigi, Weiss, Andreas, Graus Porta, Diana, Fairhurst, Robin A, Kullak-Ublick, Gerd A, Chibout, Salah-Dine, Pognan, Francois, Kluwe, William, Kinyamu-Akunda, Jacqueline
Published in Toxicological sciences (01.05.2018)
Published in Toxicological sciences (01.05.2018)
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Neurofilament Light Chain: A Translational Safety Biomarker for Drug-Induced Peripheral Neurotoxicity
Theil, Diethilde, Kuhle, Jens, Brees, Dominique, Tritto, Elaine, Pognan, François, Frieauff, Wilfried, Penraat, Kelley, Meseck, Emily, Valdez, Reginald, Hartmann, Andreas
Published in Toxicologic pathology (01.04.2023)
Published in Toxicologic pathology (01.04.2023)
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Perturbation of microRNAs in rat heart during chronic doxorubicin treatment
Vacchi-Suzzi, Caterina, Bauer, Yasmina, Berridge, Brian R, Bongiovanni, Sandrine, Gerrish, Kevin, Hamadeh, Hisham K, Letzkus, Martin, Lyon, Jonathan, Moggs, Jonathan, Paules, Richard S, Pognan, François, Staedtler, Frank, Vidgeon-Hart, Martin P, Grenet, Olivier, Couttet, Philippe
Published in PloS one (31.07.2012)
Published in PloS one (31.07.2012)
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Legacy data sharing to improve drug safety assessment: the eTOX project
Sanz, Ferran, Pognan, François, Steger-Hartmann, Thomas, Díaz, Carlos, Cases, Montserrat, Pastor, Manuel, Marc, Philippe, Wichard, Joerg, Briggs, Katharine, Watson, David K., Kleinöder, Thomas, Yang, Chihae, Amberg, Alexander, Beaumont, Maria, Brookes, Anthony J., Brunak, Søren, Cronin, Mark T. D., Ecker, Gerhard F., Escher, Sylvia, Greene, Nigel, Guzmán, Antonio, Hersey, Anne, Jacques, Pascale, Lammens, Lieve, Mestres, Jordi, Muster, Wolfgang, Northeved, Helle, Pinches, Marc, Saiz, Javier, Sajot, Nicolas, Valencia, Alfonso, van der Lei, Johan, Vermeulen, Nico P. E., Vock, Esther, Wolber, Gerhard, Zamora, Ismael
Published in Nature reviews. Drug discovery (01.12.2017)
Published in Nature reviews. Drug discovery (01.12.2017)
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OntoBrowser: a collaborative tool for curation of ontologies by subject matter experts
Ravagli, Carlo, Pognan, Francois, Marc, Philippe
Published in Bioinformatics (Oxford, England) (01.01.2017)
Published in Bioinformatics (Oxford, England) (01.01.2017)
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Reduced Activity of Sphingosine-1-Phosphate Lyase Induces Podocyte-related Glomerular Proteinuria, Skin Irritation, and Platelet Activation
Schümann, Jens, Grevot, Armelle, Ledieu, David, Wolf, Armin, Schubart, Anna, Piaia, Alessandro, Sutter, Esther, Côté, Serge, Beerli, Christian, Pognan, François, Billich, Andreas, Moulin, Pierre, Walker, Ursula Junker
Published in Toxicologic pathology (01.07.2015)
Published in Toxicologic pathology (01.07.2015)
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The evolving role of investigative toxicology in the pharmaceutical industry
Pognan, Francois, Beilmann, Mario, Boonen, Harrie C. M., Czich, Andreas, Dear, Gordon, Hewitt, Philip, Mow, Tomas, Oinonen, Teija, Roth, Adrian, Steger-Hartmann, Thomas, Valentin, Jean-Pierre, Van Goethem, Freddy, Weaver, Richard J., Newham, Peter
Published in Nature reviews. Drug discovery (01.04.2023)
Published in Nature reviews. Drug discovery (01.04.2023)
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Inroads to predict in vivo toxicology-an introduction to the eTOX Project
Briggs, Katharine, Cases, Montserrat, Heard, David J, Pastor, Manuel, Pognan, François, Sanz, Ferran, Schwab, Christof H, Steger-Hartmann, Thomas, Sutter, Andreas, Watson, David K, Wichard, Jörg D
Published in International Journal of Molecular Sciences (01.03.2012)
Published in International Journal of Molecular Sciences (01.03.2012)
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