Validating therapeutic targets through human genetics
Plenge, Robert M., Scolnick, Edward M., Altshuler, David
Published in Nature reviews. Drug discovery (01.08.2013)
Published in Nature reviews. Drug discovery (01.08.2013)
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Molecular Underpinnings of Severe Coronavirus Disease 2019
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Genomic atlas of the human plasma proteome
Sun, Benjamin B., Maranville, Joseph C., Peters, James E., Stacey, David, Staley, James R., Blackshaw, James, Burgess, Stephen, Jiang, Tao, Paige, Ellie, Surendran, Praveen, Oliver-Williams, Clare, Kamat, Mihir A., Prins, Bram P., Wilcox, Sheri K., Zimmerman, Erik S., Chi, An, Bansal, Narinder, Spain, Sarah L., Wood, Angela M., Morrell, Nicholas W., Bradley, John R., Janjic, Nebojsa, Roberts, David J., Ouwehand, Willem H., Todd, John A., Soranzo, Nicole, Suhre, Karsten, Paul, Dirk S., Fox, Caroline S., Plenge, Robert M., Danesh, John, Runz, Heiko, Butterworth, Adam S.
Published in Nature (London) (01.06.2018)
Published in Nature (London) (01.06.2018)
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Journal Article
Defining the role of the MHC in autoimmunity: a review and pooled analysis
Fernando, Michelle M A, Stevens, Christine R, Walsh, Emily C, De Jager, Philip L, Goyette, Philippe, Plenge, Robert M, Vyse, Timothy J, Rioux, John D
Published in PLoS genetics (01.04.2008)
Published in PLoS genetics (01.04.2008)
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Journal Article
Sequential immunotherapy: towards cures for autoimmunity
Ramírez-Valle, Francisco, Maranville, Joseph C., Roy, Sophie, Plenge, Robert M.
Published in Nature reviews. Drug discovery (01.07.2024)
Published in Nature reviews. Drug discovery (01.07.2024)
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Author Correction: Sequential immunotherapy: towards cures for autoimmunity
Ramírez-Valle, Francisco, Maranville, Joseph C., Roy, Sophie, Plenge, Robert M.
Published in Nature reviews. Drug discovery (01.09.2024)
Published in Nature reviews. Drug discovery (01.09.2024)
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Journal Article
Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts
Liao, Katherine P, Ananthakrishnan, Ashwin N, Kumar, Vishesh, Xia, Zongqi, Cagan, Andrew, Gainer, Vivian S, Goryachev, Sergey, Chen, Pei, Savova, Guergana K, Agniel, Denis, Churchill, Susanne, Lee, Jaeyoung, Murphy, Shawn N, Plenge, Robert M, Szolovits, Peter, Kohane, Isaac, Shaw, Stanley Y, Karlson, Elizabeth W, Cai, Tianxi
Published in PloS one (24.08.2015)
Published in PloS one (24.08.2015)
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Principal components analysis corrects for stratification in genome-wide association studies
Price, Alkes L, Patterson, Nick J, Plenge, Robert M, Weinblatt, Michael E, Shadick, Nancy A, Reich, David
Published in Nature genetics (01.08.2006)
Published in Nature genetics (01.08.2006)
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Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
Raychaudhuri, Soumya, Sandor, Cynthia, Stahl, Eli A, Freudenberg, Jan, Lee, Hye-Soon, Jia, Xiaoming, Alfredsson, Lars, Padyukov, Leonid, Klareskog, Lars, Worthington, Jane, Siminovitch, Katherine A, Bae, Sang-Cheol, Plenge, Robert M, Gregersen, Peter K, de Bakker, Paul I W
Published in Nature genetics (01.03.2012)
Published in Nature genetics (01.03.2012)
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The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1
Li, Gang, Cunin, Pierre, Wu, Di, Diogo, Dorothée, Yang, Yu, Okada, Yukinori, Plenge, Robert M, Nigrovic, Peter A
Published in PLoS genetics (14.09.2016)
Published in PLoS genetics (14.09.2016)
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High-throughput phenotyping with electronic medical record data using a common semi-supervised approach (PheCAP)
Zhang, Yichi, Cai, Tianrun, Yu, Sheng, Cho, Kelly, Hong, Chuan, Sun, Jiehuan, Huang, Jie, Ho, Yuk-Lam, Ananthakrishnan, Ashwin N., Xia, Zongqi, Shaw, Stanley Y., Gainer, Vivian, Castro, Victor, Link, Nicholas, Honerlaw, Jacqueline, Huang, Sicong, Gagnon, David, Karlson, Elizabeth W., Plenge, Robert M., Szolovits, Peter, Savova, Guergana, Churchill, Susanne, O’Donnell, Christopher, Murphy, Shawn N., Gaziano, J. Michael, Kohane, Isaac, Cai, Tianxi, Liao, Katherine P.
Published in Nature protocols (01.12.2019)
Published in Nature protocols (01.12.2019)
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Epidemiology and treatment patterns of rheumatoid arthritis in a large cohort of Arab patients
Dargham, Soha R, Zahirovic, Sumeja, Hammoudeh, Mohammed, Al Emadi, Samar, Masri, Basel K, Halabi, Hussein, Badsha, Humeira, Uthman, Imad, Mahfoud, Ziyad R, Ashour, Hadil, Gad El Haq, Wissam, Bayoumy, Karim, Kapiri, Marianthi, Saxena, Richa, Plenge, Robert M, Kazkaz, Layla, Arayssi, Thurayya
Published in PloS one (19.12.2018)
Published in PloS one (19.12.2018)
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Automatic prediction of rheumatoid arthritis disease activity from the electronic medical records
Lin, Chen, Karlson, Elizabeth W, Canhao, Helena, Miller, Timothy A, Dligach, Dmitriy, Chen, Pei Jun, Perez, Raul Natanael Guzman, Shen, Yuanyan, Weinblatt, Michael E, Shadick, Nancy A, Plenge, Robert M, Savova, Guergana K
Published in PloS one (16.08.2013)
Published in PloS one (16.08.2013)
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Quantifying missing heritability at known GWAS loci
Gusev, Alexander, Bhatia, Gaurav, Zaitlen, Noah, Vilhjalmsson, Bjarni J, Diogo, Dorothée, Stahl, Eli A, Gregersen, Peter K, Worthington, Jane, Klareskog, Lars, Raychaudhuri, Soumya, Plenge, Robert M, Pasaniuc, Bogdan, Price, Alkes L
Published in PLoS genetics (01.12.2013)
Published in PLoS genetics (01.12.2013)
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Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity
Han, Buhm, Diogo, Dorothée, Eyre, Steve, Kallberg, Henrik, Zhernakova, Alexandra, Bowes, John, Padyukov, Leonid, Okada, Yukinori, González-Gay, Miguel A., Rantapää-Dahlqvist, Solbritt, Martin, Javier, Huizinga, Tom W.J., Plenge, Robert M., Worthington, Jane, Gregersen, Peter K., Klareskog, Lars, de Bakker, Paul I.W., Raychaudhuri, Soumya
Published in American journal of human genetics (03.04.2014)
Published in American journal of human genetics (03.04.2014)
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