Cell Adhesion Mechanisms in Platelets
Varga-Szabo, David, Pleines, Irina, Nieswandt, Bernhard
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2008)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2008)
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Orai1 (CRACM1) is the platelet SOC channel and essential for pathological thrombus formation
Braun, Attila, Varga-Szabo, David, Kleinschnitz, Christoph, Pleines, Irina, Bender, Markus, Austinat, Madeleine, Bösl, Michael, Stoll, Guido, Nieswandt, Bernhard
Published in Blood (26.02.2009)
Published in Blood (26.02.2009)
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Journal Article
CLEC-2 is an essential platelet-activating receptor in hemostasis and thrombosis
May, Frauke, Hagedorn, Ina, Pleines, Irina, Bender, Markus, Vögtle, Timo, Eble, Johannes, Elvers, Margitta, Nieswandt, Bernhard
Published in Blood (15.10.2009)
Published in Blood (15.10.2009)
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Journal Article
Factor XIIa Inhibitor Recombinant Human Albumin Infestin-4 Abolishes Occlusive Arterial Thrombus Formation Without Affecting Bleeding
HAGEDORN, Ina, SCHMIDBAUER, Stefan, PLEINES, Irina, KLEINSCHNITZ, Christoph, KRONTHALER, Ulrich, STOLL, Guido, DICKNEITE, Gerhard, NIESWANDT, Bernhard
Published in Circulation (New York, N.Y.) (06.04.2010)
Published in Circulation (New York, N.Y.) (06.04.2010)
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Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis
Pleines, Irina, Hagedorn, Ina, Gupta, Shuchi, May, Frauke, Chakarova, Lidija, van Hengel, Jolanda, Offermanns, Stefan, Krohne, Georg, Kleinschnitz, Christoph, Brakebusch, Cord, Nieswandt, Bernhard
Published in Blood (26.01.2012)
Published in Blood (26.01.2012)
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Journal Article
Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42
Pleines, Irina, Dütting, Sebastian, Cherpokova, Deya, Eckly, Anita, Meyer, Imke, Morowski, Martina, Krohne, Georg, Schulze, Harald, Gachet, Christian, Debili, Najet, Brakebusch, Cord, Nieswandt, Bernhard
Published in Blood (31.10.2013)
Published in Blood (31.10.2013)
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Journal Article
Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo
Nieswandt, Bernhard, Moser, Markus, Pleines, Irina, Varga-Szabo, David, Monkley, Sue, Critchley, David, Fässler, Reinhard
Published in The Journal of experimental medicine (24.12.2007)
Published in The Journal of experimental medicine (24.12.2007)
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Journal Article
The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction
Varga-Szabo, David, Braun, Attila, Kleinschnitz, Christoph, Bender, Markus, Pleines, Irina, Pham, Mirko, Renné, Thomas, Stoll, Guido, Nieswandt, Bernhard
Published in The Journal of experimental medicine (07.07.2008)
Published in The Journal of experimental medicine (07.07.2008)
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A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis
Dütting, Sebastian, Gaits-Iacovoni, Frederique, Stegner, David, Popp, Michael, Antkowiak, Adrien, van Eeuwijk, Judith M.M., Nurden, Paquita, Stritt, Simon, Heib, Tobias, Aurbach, Katja, Angay, Oguzhan, Cherpokova, Deya, Heinz, Niels, Baig, Ayesha A., Gorelashvili, Maximilian G., Gerner, Frank, Heinze, Katrin G., Ware, Jerry, Krohne, Georg, Ruggeri, Zaverio M., Nurden, Alan T., Schulze, Harald, Modlich, Ute, Pleines, Irina, Brakebusch, Cord, Nieswandt, Bernhard
Published in Nature communications (15.06.2017)
Published in Nature communications (15.06.2017)
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Journal Article
Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets
Pleines, Irina, Eckly, Anita, Elvers, Margitta, Hagedorn, Ina, Eliautou, Sandra, Bender, Markus, Wu, Xunwei, Lanza, Francois, Gachet, Christian, Brakebusch, Cord, Nieswandt, Bernhard
Published in Blood (22.04.2010)
Published in Blood (22.04.2010)
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Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan
Liu, Zhi-Jian, Hoffmeister, Karin M., Hu, Zhongbo, Mager, Donald E., Ait-Oudhia, Sihem, Debrincat, Marlyse A., Pleines, Irina, Josefsson, Emma C., Kile, Benjamin T., Italiano, Joseph, Ramsey, Haley, Grozovsky, Renata, Veng-Pedersen, Peter, Chavda, Chaitanya, Sola-Visner, Martha
Published in Blood (29.05.2014)
Published in Blood (29.05.2014)
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Coactosin-like 1 integrates signaling critical for shear-dependent thrombus formation in mouse platelets
Scheller, Inga, Stritt, Simon, Beck, Sarah, Peng, Bing, Pleines, Irina, Heinze, Katrin G, Braun, Attila, Otto, Oliver, Ahrends, Robert, Sickmann, Albert, Bender, Markus, Nieswandt, Bernhard
Published in Haematologica (Roma) (01.06.2020)
Published in Haematologica (Roma) (01.06.2020)
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ADF/n-cofilin–dependent actin turnover determines platelet formation and sizing
Bender, Markus, Eckly, Anita, Hartwig, John H., Elvers, Margitta, Pleines, Irina, Gupta, Shuchi, Krohne, Georg, Jeanclos, Elisabeth, Gohla, Antje, Gurniak, Christine, Gachet, Christian, Witke, Walter, Nieswandt, Bernhard
Published in Blood (09.09.2010)
Published in Blood (09.09.2010)
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Critical redundant functions of the adapters Grb2 and Gads in platelet (hem)ITAM signaling in mice
Vögtle, Timo, Baig, Ayesha A., Volz, Julia, Duchow, Timothy B., Pleines, Irina, Dütting, Sebastian, Nitschke, Lars, Watson, Stephen P., Nieswandt, Bernhard
Published in Platelets (Edinburgh) (17.08.2020)
Published in Platelets (Edinburgh) (17.08.2020)
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Journal Article
Deficiency of the Tetraspanin CD63 Associated with Kidney Pathology but Normal Lysosomal Function
Schröder, Jenny, Lüllmann-Rauch, Renate, Himmerkus, Nina, Pleines, Irina, Nieswandt, Bernhard, Orinska, Zane, Koch-Nolte, Friedrich, Schröder, Bernd, Bleich, Markus, Saftig, Paul
Published in Molecular and Cellular Biology (01.02.2009)
Published in Molecular and Cellular Biology (01.02.2009)
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Journal Article
An essential role for α4A-tubulin in platelet biogenesis
Strassel, Catherine, Magiera, Maria M, Dupuis, Arnaud, Batzenschlager, Morgane, Hovasse, Agnès, Pleines, Irina, Guéguen, Paul, Eckly, Anita, Moog, Sylvie, Mallo, Léa, Kimmerlin, Quentin, Chappaz, Stéphane, Strub, Jean-Marc, Kathiresan, Natarajan, de la Salle, Henri, Van Dorsselaer, Alain, Ferec, Claude, Py, Jean-Yves, Gachet, Christian, Schaeffer-Reiss, Christine, Kile, Benjamin T, Janke, Carsten, Lanza, François
Published in Life science alliance (01.02.2019)
Published in Life science alliance (01.02.2019)
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